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A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128113-128113, Article 128113

2021

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BacMam production and crystal structure of nonglycosylated apo human furin at 1.89 Å resolution

Acta crystallographica. Section F, Structural biology communications, 2019-04, Vol.75 (4), p.239-245

2019

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Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (4), p.1399-1404

2010

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Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction

Nature structural & molecular biology, 2010-07, Vol.17 (7), p.808

2010

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Solution Structure of the Human pp60c-src SH2 Domain Complexed with a Phosphorylated Tyrosine Pentapeptide

Biochemistry (Easton), 1995-02, Vol.34 (7), p.2107-2121

1995

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Catalytic Activity of the SH2 Domain of Human pp60c-src; Evidence from NMR, Mass Spectrometry, Site-Directed Mutagenesis and Kinetic Studies for an Inherent Phosphatase Activity

Biochemistry (Easton), 1995-11, Vol.34 (46), p.15351-15358

1995

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1-Methylphenanthro[3,4-b]thiophene: Determination of the tertiary structure in solution and in the crystalline state by NMR spectroscopy and X-ray diffraction

Journal of heterocyclic chemistry, 1985-03, Vol.22 (2), p.545-553

1985

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Heteronuclear three-dimensional NMR spectroscopy. Natural abundance carbon-13 chemical shift editing of 1H-1H COSY spectra

Journal of the American Chemical Society, 1989-01, Vol.111 (2), p.770-772

1989

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Pseudo-four-dimensional NMR by off-resonance decoupling: an approach for distinguishing coupled proton pairs by the frequencies of their attached heteronuclei

Journal of the American Chemical Society, 1990-06, Vol.112 (13), p.5370-5371

1990

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Total assignment of the carbon-13 NMR spectrum of the cembranoid diterpene eunicin through the use of two-dimensional proton-carbon chemical shift correlation

Journal of the American Chemical Society, 1984-03, Vol.106 (6), p.1823-1826

1984

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Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327-2327

2002

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Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327-2327

2002

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Chemistry of the phenoxathiins and isosterically related heterocycles. XIV. Total assignment of the 13C-Nmr spectrum of pyrrolo[3,2,1-kl]phenothiazine

Journal of heterocyclic chemistry, 1981-01, Vol.18 (1), p.155-161

1981

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Homonuclear two-dimensional J-resolved spectroscopy. The examination of resonances due to strong coupling in the two-dimensional J-spectrum of 1,6-diazathianthrene: The role of first order character in the position and intensity of resonances due to strong coupling

Journal of heterocyclic chemistry, 1983-01, Vol.20 (1), p.253-256

1983

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Chemistry of the phenoxathiins and isosterically related heterocycles. XXVII. Two-dimensional J-resolved spectra of 1,4,9-triazaphenoxathiin: The influence of frequency of the position and intensity of resonances due to strong coupling

Journal of heterocyclic chemistry, 1983-07, Vol.20 (4), p.1063-1075

1983

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Assignment of the 13C-NMR spectrum of phenanthro[4,3-A]dibenzothiophene through the utilization of two-dimensional relayed coherence transfer and double quantum coherence spectroscopy

Journal of heterocyclic chemistry, 1985-01, Vol.22 (1), p.219-223

1985

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Autocorrelated 13c-13c double quantum coherence two-dimensional nmr spectroscopy: Utilization of a modified version of the technique as an adjunct in the total assignment of the 1h- and 13c-nmr spectra of the mutagen phenanthro[3,4-b]thiophene

Journal of heterocyclic chemistry, 1983-11, Vol.20 (6), p.1661-1669

1983

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Combined application of auto-correlated (COSY) and homonuclear J-resolved two-dimensional NMR spectra for the assignment of congested, non-first order spectra of polycyclic aromatic systems. Assignment of the 1H-NMR spectrum of benzo[2,3]phenanthro-[4,5-bcd]thiophene and an investigation of long range 1H-1H spin-coupling constants

Journal of heterocyclic chemistry, 1984-01, Vol.21 (1), p.225-233

1984

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Heteronuclear three-dimensional NMR spectroscopy applied to CMP-KDO synthetase (27.5 kD)

Biochemical and biophysical research communications, 1989-03, Vol.159 (2), p.842-847

1989

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Retraction

Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Retraction

Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Retraction

Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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Retraction

Science (American Association for the Advancement of Science), 2002-12, Vol.298 (5602), p.2327

2002

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A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors

BacMam production and crystal structure of nonglycosylated apo human furin at 1.89 Å resolution

Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators

Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1 H -indol-5-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

Solution Structure of the Human pp60c-src SH2 Domain Complexed with a Phosphorylated Tyrosine Pentapeptide

Catalytic Activity of the SH2 Domain of Human pp60c-src; Evidence from NMR, Mass Spectrometry, Site-Directed Mutagenesis and Kinetic Studies for an Inherent Phosphatase Activity

1-Methylphenanthro[3,4-b]thiophene: Determination of the tertiary structure in solution and in the crystalline state by NMR spectroscopy and X-ray diffraction

Heteronuclear three-dimensional NMR spectroscopy. Natural abundance carbon-13 chemical shift editing of 1H-1H COSY spectra

Pseudo-four-dimensional NMR by off-resonance decoupling: an approach for distinguishing coupled proton pairs by the frequencies of their attached heteronuclei

Total assignment of the carbon-13 NMR spectrum of the cembranoid diterpene eunicin through the use of two-dimensional proton-carbon chemical shift correlation

Retraction

Retraction

Retraction

Chemistry of the phenoxathiins and isosterically related heterocycles. XIV. Total assignment of the 13C-Nmr spectrum of pyrrolo[3,2,1-kl]phenothiazine

Homonuclear two-dimensional J-resolved spectroscopy. The examination of resonances due to strong coupling in the two-dimensional J-spectrum of 1,6-diazathianthrene: The role of first order character in the position and intensity of resonances due to strong coupling

Chemistry of the phenoxathiins and isosterically related heterocycles. XXVII. Two-dimensional J-resolved spectra of 1,4,9-triazaphenoxathiin: The influence of frequency of the position and intensity of resonances due to strong coupling

Assignment of the 13C-NMR spectrum of phenanthro[4,3-A]dibenzothiophene through the utilization of two-dimensional relayed coherence transfer and double quantum coherence spectroscopy

Autocorrelated 13c-13c double quantum coherence two-dimensional nmr spectroscopy: Utilization of a modified version of the technique as an adjunct in the total assignment of the 1h- and 13c-nmr spectra of the mutagen phenanthro[3,4-b]thiophene

Heteronuclear three-dimensional NMR spectroscopy applied to CMP-KDO synthetase (27.5 kD)

Retraction

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