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Comparative Electroencephalographic Profile of a New Anesthetic and Anticonvulsant That Is Selective for the GABAAR Slow Receptor Subtype

Anesthesia and analgesia, 2024-10

2024

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Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (8), p.1-8

2021

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Modulation of α1β3γ2 GABA A receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (8)

2021

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Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of α1 glycine receptors

Journal of neurochemistry, 2007-09, Vol.102 (6), p.2097-2109

2007

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Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors

ACS chemical neuroscience, 2016-01, Vol.7 (1), p.100-108

2016

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Assessment of homology templates and an anesthetic binding site within the ?-aminobutyric acid receptor

Anesthesiology (Philadelphia), 2013-11, Vol.119 (5), p.1087

2013

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Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn2+ in GABAA αβ Receptors and Provides a Structural Basis for the Modulating Effect of the γ Subunit

Journal of chemical information and modeling, 2008-02, Vol.48 (2), p.344-349

2008

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Principal Components from Ligand-Gated Ion Channel Structures Enable Ensemble Studies of Microsecond-Scale Transitions

Biophysical journal, 2016-02, Vol.110 (3), p.454a-454a

2016

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Identification of an Inhibitory Alcohol Binding Site in GABAaRho1

Biophysical journal, 2016-02, Vol.110 (3), p.428a-428a

2016

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Contribution of Structural Elements to Activation and Allosteric Modulation in an Anionic Ligand-Gated Ion Channel

Biophysical journal, 2014, Vol.106 (2), p.547a-547a

2014

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The Molecular Mechanism for the Dual Alcohol Modulation of Cys-Loop Receptors

Biophysical journal, 2012, Vol.102 (3), p.112a-112a

2012

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Roles for Loop 2 Residues of α1 Glycine Receptors in Agonist Activation

The Journal of biological chemistry, 2008-10, Vol.283 (41), p.27698-27706

2008

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Identification of an Inhibitory Alcohol Binding Site in GABA A ρ1 Receptors

ACS chemical neuroscience, 2016-01, Vol.7 (1), p.100-108

2016

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Normal-Mode Analysis of the Glycine Alphal Receptor by Three Separate Methods

Journal of chemical information and modeling, 2007-07, Vol.47 (4), p.1572

2007

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Roles for Loop 2 Residues of Î±1 Glycine Receptors in Agonist Activation

The Journal of biological chemistry, 2008-10, Vol.283 (41), p.27698

2008

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Roles for loop 2 residues of alpha1 glycine receptors in agonist activation

The Journal of biological chemistry, 2008-10, Vol.283 (41), p.27698

2008

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Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn 2+ in GABA A αβ Receptors and Provides a Structural Basis for the Modulating Effect of the γ Subunit

Journal of chemical information and modeling, 2008-02, Vol.48 (2), p.344-349

2008

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Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn^sup 2+^ in GABA^sub A^ [alpha][beta] Receptors and Provides a Structural Basis for the Modulating Effect of the [gamma] Subunit

Journal of chemical information and modeling, 2008-02, Vol.48 (2), p.344

2008

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Molecular modeling and mutagenesis reveals a tetradentate binding site for Zn2+ in GABA(A) alphabeta receptors and provides a structural basis for the modulating effect of the gamma subunit

Journal of chemical information and modeling, 2008-02, Vol.48 (2), p.344

2008

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Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors

Journal of neurochemistry, 2007-09, Vol.102 (6), p.2097

2007

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Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of [alpha]1 glycine receptors

Journal of neurochemistry, 2007-09, Vol.102 (6), p.2097

2007

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Molecular Modeling of Anesthetic Binding Sites within a Composite Glycine Receptor: 2002[A-121

Anesthesiology (Philadelphia), 2002-09, Vol.96 (Sup 2), p.A121

2002

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Room 302, 10/16/2000 9: 00 AM - 10: 30 AM (PD) Prediction of the Tertiary Structure of an Anesthetic Binding Site

Anesthesiology (Philadelphia), 2000-09, Vol.93 (3A), p.A-120

2000

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Docking of Anesthetics to a GABA Receptor Model Reproduces In Vitro Potency Order: 2002[A-116

Anesthesiology (Philadelphia), 2002-09, Vol.96 (Sup 2), p.A116

2002

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ChemInform Abstract: Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn 2+ in GABA A αβ Receptors and Provides a Structural Basis for the Modulating Effect of the γ Subunit

ChemInform, 2008-05, Vol.39 (21)

2008

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Comparative Electroencephalographic Profile of a New Anesthetic and Anticonvulsant That Is Selective for the GABAAR Slow Receptor Subtype

Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

Modulation of α1β3γ2 GABA A receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helix

Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of α1 glycine receptors

Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors

Assessment of homology templates and an anesthetic binding site within the ?-aminobutyric acid receptor

Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn2+ in GABAA αβ Receptors and Provides a Structural Basis for the Modulating Effect of the γ Subunit

Principal Components from Ligand-Gated Ion Channel Structures Enable Ensemble Studies of Microsecond-Scale Transitions

Identification of an Inhibitory Alcohol Binding Site in GABAaRho1

Contribution of Structural Elements to Activation and Allosteric Modulation in an Anionic Ligand-Gated Ion Channel

The Molecular Mechanism for the Dual Alcohol Modulation of Cys-Loop Receptors

Roles for Loop 2 Residues of α1 Glycine Receptors in Agonist Activation

Identification of an Inhibitory Alcohol Binding Site in GABA A ρ1 Receptors

Normal-Mode Analysis of the Glycine Alphal Receptor by Three Separate Methods

Roles for Loop 2 Residues of Î±1 Glycine Receptors in Agonist Activation

Roles for loop 2 residues of alpha1 glycine receptors in agonist activation

Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn 2+ in GABA A αβ Receptors and Provides a Structural Basis for the Modulating Effect of the γ Subunit

Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn^sup 2+^ in GABA^sub A^ [alpha][beta] Receptors and Provides a Structural Basis for the Modulating Effect of the [gamma] Subunit

Molecular modeling and mutagenesis reveals a tetradentate binding site for Zn2+ in GABA(A) alphabeta receptors and provides a structural basis for the modulating effect of the gamma subunit

Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors

Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of [alpha]1 glycine receptors

Molecular Modeling of Anesthetic Binding Sites within a Composite Glycine Receptor: 2002[A-121

Room 302, 10/16/2000 9: 00 AM - 10: 30 AM (PD) Prediction of the Tertiary Structure of an Anesthetic Binding Site

Docking of Anesthetics to a GABA Receptor Model Reproduces In Vitro Potency Order: 2002[A-116

ChemInform Abstract: Molecular Modeling and Mutagenesis Reveals a Tetradentate Binding Site for Zn 2+ in GABA A αβ Receptors and Provides a Structural Basis for the Modulating Effect of the γ Subunit

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