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The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

Nature (London), 2011-01, Vol.469 (7329), p.241-244

2011

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Structure of a β1-adrenergic G-protein-coupled receptor

Nature (London), 2008-07, Vol.454 (7203), p.486-491

2008

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The signaling and selectivity of α‐adrenoceptor agonists for the human α2A, α2B and α2C‐adrenoceptors and comparison with human α1 and β‐adrenoceptors

Pharmacology research & perspectives, 2022-10, Vol.10 (5), p.e01003-n/a

2022

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The affinity and selectivity of α‐adrenoceptor antagonists, antidepressants and antipsychotics for the human α2A, α2B, and α2C‐adrenoceptors and comparison with human α1 and β‐adrenoceptors

Pharmacology research & perspectives, 2022-04, Vol.10 (2), p.e00936-n/a

2022

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The selectivity of β‐adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors

British journal of pharmacology, 2005-02, Vol.144 (3), p.317-322

Baker, Jillian G

2005

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The affinity and selectivity of α‐adrenoceptor antagonists, antidepressants, and antipsychotics for the human α1A, α1B, and α1D‐adrenoceptors

Pharmacology research & perspectives, 2020-08, Vol.8 (4), p.e00602-n/a

2020

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The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors

Pharmacology research & perspectives, 2021-08, Vol.9 (4), p.e00799-n/a

2021

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Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor

PloS one, 2013-11, Vol.8 (11), p.e77582-e77582

2013

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New Fluorescent Adenosine A1-Receptor Agonists That Allow Quantification of Ligand−Receptor Interactions in Microdomains of Single Living Cells

Journal of medicinal chemistry, 2007-02, Vol.50 (4), p.782-793

2007

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The Isoleucine at Position 118 in Transmembrane 2 Is Responsible for the Selectivity of Xamoterol, Nebivolol, and ICI89406 for the Human β 1-Adrenoceptor

Molecular pharmacology, 2023-02, Vol.103 (2), p.89-99

2023

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Negative cooperativity across β1‐adrenoceptor homodimers provides insights into the nature of the secondary low‐affinity CGP 12177 β1‐adrenoceptor binding conformation

The FASEB journal, 2015-07, Vol.29 (7), p.2859-2871

2015

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Pharmacological and SAR analysis of the LINS01 compounds at the human histamine H 1 , H 2 , and H 3 receptors

Chemical biology & drug design, 2019-01, Vol.93 (1), p.89

2019

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Salmeterol's extreme β2 selectivity is due to residues in both extracellular loops and transmembrane domains

Molecular pharmacology, 2015-01, Vol.87 (1), p.103

2015

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Similarity- and Substructure-Based Development of β2‑Adrenergic Receptor Ligands Based on Unusual Scaffolds

ACS medicinal chemistry letters, 2017-05, Vol.8 (5), p.481-485

2017

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Novel selective β1‐adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

The FASEB journal, 2017-07, Vol.31 (7), p.3150-3166

2017

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Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human β1-adrenoceptor

Molecular pharmacology, 2014-05, Vol.85 (5), p.811-829

2014

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Pharmacological characterization of CGP 12177 at the human β 2 ‐adrenoceptor

British journal of pharmacology, 2009-02, Vol.137 (3), p.400-408

2009

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Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells

BMC pharmacology, 2008-06, Vol.8 (9), p.9-9, Article 9

Baker, Jillian G

2008

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Novel selective β 1 -adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

The FASEB journal, 2017-07, Vol.31 (7), p.3150-3166

2017

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Synthesis and in Vitro and in Vivo Characterization of Highly β1‑Selective β‑Adrenoceptor Partial Agonists

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.3852-3865

2013

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Pharmacology and direct visualisation of BODIPY‐TMR‐CGP: a long‐acting fluorescent β 2 ‐adrenoceptor agonist

British journal of pharmacology, 2009-01, Vol.139 (2), p.232-242

2009

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Reporter-gene systems for the study of G-protein-coupled receptors

Current Opinion in Pharmacology, 2001-10, Vol.1 (5), p.526-532

2001

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[beta]-Blockers, heart disease and COPD: current controversies and uncertainties

Thorax, 2017-03, Vol.72 (3), p.271

2017

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A comparison of the antagonist affinities for the Gi- and Gs-coupled states of the human adenosine A1-receptor

The Journal of pharmacology and experimental therapeutics, 2007-01, Vol.320 (1), p.218

2007

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A Full Pharmacological Analysis of the Three Turkey [beta]-Adrenoceptors and Comparison with the Human [beta]-Adrenoceptors

PloS one, 2010-11, Vol.5 (11), p.e15487

Baker, Jillian G

2010

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The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

Structure of a β1-adrenergic G-protein-coupled receptor

The signaling and selectivity of α‐adrenoceptor agonists for the human α2A, α2B and α2C‐adrenoceptors and comparison with human α1 and β‐adrenoceptors

The affinity and selectivity of α‐adrenoceptor antagonists, antidepressants and antipsychotics for the human α2A, α2B, and α2C‐adrenoceptors and comparison with human α1 and β‐adrenoceptors

The selectivity of β‐adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors

The affinity and selectivity of α‐adrenoceptor antagonists, antidepressants, and antipsychotics for the human α1A, α1B, and α1D‐adrenoceptors

The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors

Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor

New Fluorescent Adenosine A1-Receptor Agonists That Allow Quantification of Ligand−Receptor Interactions in Microdomains of Single Living Cells

The Isoleucine at Position 118 in Transmembrane 2 Is Responsible for the Selectivity of Xamoterol, Nebivolol, and ICI89406 for the Human β 1-Adrenoceptor

Negative cooperativity across β1‐adrenoceptor homodimers provides insights into the nature of the secondary low‐affinity CGP 12177 β1‐adrenoceptor binding conformation

Pharmacological and SAR analysis of the LINS01 compounds at the human histamine H 1 , H 2 , and H 3 receptors

Salmeterol's extreme β2 selectivity is due to residues in both extracellular loops and transmembrane domains

Similarity- and Substructure-Based Development of β2‑Adrenergic Receptor Ligands Based on Unusual Scaffolds

Novel selective β1‐adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

Identification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human β1-adrenoceptor

Pharmacological characterization of CGP 12177 at the human β 2 ‐adrenoceptor

Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells

Novel selective β 1 -adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

Synthesis and in Vitro and in Vivo Characterization of Highly β1‑Selective β‑Adrenoceptor Partial Agonists

Pharmacology and direct visualisation of BODIPY‐TMR‐CGP: a long‐acting fluorescent β 2 ‐adrenoceptor agonist

Reporter-gene systems for the study of G-protein-coupled receptors

[beta]-Blockers, heart disease and COPD: current controversies and uncertainties

A comparison of the antagonist affinities for the Gi- and Gs-coupled states of the human adenosine A1-receptor

A Full Pharmacological Analysis of the Three Turkey [beta]-Adrenoceptors and Comparison with the Human [beta]-Adrenoceptors

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