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Expanding Roles for SREBP in Metabolism

Cell metabolism, 2012-10, Vol.16 (4), p.414-419

2012

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Proximity-dependent biotin labelling in yeast using the engineered ascorbate peroxidase APEX2

Biochemical journal, 2016-08, Vol.473 (16), p.2463-2469

2016

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Lipid balance must be just right to prevent development of severe liver damage

The Journal of clinical investigation, 2022-06, Vol.132 (11), p.1-3

2022

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Regulation of sterol synthesis in eukaryotes

Annual review of genetics, 2007-01, Vol.41 (1), p.401-427

2007

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Carbon dioxide regulates cholesterol levels through SREBP2

PLoS biology, 2023-11, Vol.21 (11), p.e3002367

2023

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Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner

Journal of lipid research, 2016-08, Vol.57 (8), p.1564-1573

2016

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Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis

Eukaryotic Cell, 2010-03, Vol.9 (3), p.352-359

2010

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A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP

The EMBO journal, 2016-11, Vol.35 (21), p.2332-2349

2016

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Sugar Makes Fat by Talking to SCAP

Cancer cell, 2015-11, Vol.28 (5), p.548-549

2015

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Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum

Cell chemical biology, 2021-02, Vol.28 (2), p.169-179.e7

2021

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Endoplasmic Reticulum Exit of Golgi-resident Defective for SREBP Cleavage (Dsc) E3 Ligase Complex Requires Its Activity

The Journal of biological chemistry, 2015-06, Vol.290 (23), p.14430-14440

2015

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Coordinate Regulation of Yeast Sterol Regulatory Element-binding Protein (SREBP) and Mga2 Transcription Factors

The Journal of biological chemistry, 2017-03, Vol.292 (13), p.5311-5324

2017

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SREBP Pathway Responds to Sterols and Functions as an Oxygen Sensor in Fission Yeast

Cell, 2005-03, Vol.120 (6), p.831-842

2005

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Identification of Candidate Substrates for the Golgi Tul1 E3 Ligase Using Quantitative diGly Proteomics in Yeast

Molecular & cellular proteomics, 2014-11, Vol.13 (11), p.2871-2882

2014

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In vivo CRISPR screening identifies geranylgeranyl diphosphate as a pancreatic cancer tumor growth dependency

Molecular metabolism (Germany), 2024-07, Vol.85, p.101964, Article 101964

2024

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Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans

Molecular microbiology, 2007-05, Vol.64 (3), p.614-629

2007

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Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast

The Journal of biological chemistry, 2017-09, Vol.292 (39), p.16333-16350

2017

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Sterol Regulatory Element-Binding Protein (Sre1) Promotes the Synthesis of Carotenoids and Sterols in Xanthophyllomyces dendrorhous

Frontiers in microbiology, 2019-03, Vol.10, p.586-586

2019

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Subunit Architecture of the Golgi Dsc E3 Ligase Required for Sterol Regulatory Element-binding Protein (SREBP) Cleavage in Fission Yeast

The Journal of biological chemistry, 2013-07, Vol.288 (29), p.21043-21054

2013

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Targeting Stearoyl-CoA Desaturase in Solid Tumors

Cancer research (Chicago, Ill.), 2022-05, Vol.82 (9), p.1682-1688

2022

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Sterol Regulatory Element-binding Protein (SREBP) Cleavage Regulates Golgi-to-Endoplasmic Reticulum Recycling of SREBP Cleavage-activating Protein (SCAP)

The Journal of biological chemistry, 2014-03, Vol.289 (11), p.7547-7557

2014

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PGRMC1: An enigmatic heme-binding protein

Pharmacology & therapeutics (Oxford), 2023-01, Vol.241, p.108326-108326, Article 108326

2023

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Cytosolic 5'-Nucleotidase III and Nucleoside Triphosphate Diphosphohydrolase 1 Dephosphorylate the Pharmacologically Active Metabolites of Gemcitabine and Emtricitabine

Drug metabolism and disposition, 2024-04, Vol.52 (4), p.288-295

2024

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Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

Genes & development, 2009-11, Vol.23 (22), p.2578-2591

2009

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Commercial lipoprotein-deficient sera differ in iron content

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2023-02, Vol.1868 (2), p.159260-159260, Article 159260

2023

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Expanding Roles for SREBP in Metabolism

Proximity-dependent biotin labelling in yeast using the engineered ascorbate peroxidase APEX2

Lipid balance must be just right to prevent development of severe liver damage

Regulation of sterol synthesis in eukaryotes

Carbon dioxide regulates cholesterol levels through SREBP2

Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner

Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis

A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP

Sugar Makes Fat by Talking to SCAP

Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum

Endoplasmic Reticulum Exit of Golgi-resident Defective for SREBP Cleavage (Dsc) E3 Ligase Complex Requires Its Activity

Coordinate Regulation of Yeast Sterol Regulatory Element-binding Protein (SREBP) and Mga2 Transcription Factors

SREBP Pathway Responds to Sterols and Functions as an Oxygen Sensor in Fission Yeast

Identification of Candidate Substrates for the Golgi Tul1 E3 Ligase Using Quantitative diGly Proteomics in Yeast

In vivo CRISPR screening identifies geranylgeranyl diphosphate as a pancreatic cancer tumor growth dependency

Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans

Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast

Sterol Regulatory Element-Binding Protein (Sre1) Promotes the Synthesis of Carotenoids and Sterols in Xanthophyllomyces dendrorhous

Subunit Architecture of the Golgi Dsc E3 Ligase Required for Sterol Regulatory Element-binding Protein (SREBP) Cleavage in Fission Yeast

Targeting Stearoyl-CoA Desaturase in Solid Tumors

Sterol Regulatory Element-binding Protein (SREBP) Cleavage Regulates Golgi-to-Endoplasmic Reticulum Recycling of SREBP Cleavage-activating Protein (SCAP)

PGRMC1: An enigmatic heme-binding protein

Cytosolic 5'-Nucleotidase III and Nucleoside Triphosphate Diphosphohydrolase 1 Dephosphorylate the Pharmacologically Active Metabolites of Gemcitabine and Emtricitabine

Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

Commercial lipoprotein-deficient sera differ in iron content

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