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Orthosteric versus allosteric GPCR activation: The great challenge of group-III mGluRs

Biochemical pharmacology, 2012-08, Vol.84 (4), p.414-424

2012

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The Emerging Role of Metabotropic Glutamate Receptors in the Pathophysiology of Chronic Stress-Related Disorders

Current neuropharmacology, 2016-07, Vol.14 (5), p.514-539

2016

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Metabotropic Glutamate Receptor Subtype 7 in the Bed Nucleus of the Stria Terminalis is Essential for Intermale Aggression

Neuropsychopharmacology (New York, N.Y.), 2016-02, Vol.41 (3), p.726-735

2016

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Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues

Pharmacological reviews, 2011-03, Vol.63 (1), p.35

2011

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Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) via the Venus Flytrap Domain (VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior

The Journal of biological chemistry, 2014-04, Vol.289 (16), p.10975-10987

2014

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Activation of the mGlu7 receptor elicits antidepressant-like effects in mice

Psychopharmacologia, 2007-11, Vol.194 (4), p.555-562

2007

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Metabotropic glutamate receptor 7: At the interface of cognition and emotion

European journal of pharmacology, 2010-08, Vol.639 (1), p.123-131

2010

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A Selective Metabotropic Glutamate Receptor 7 Agonist: Activation of Receptor Signaling via an Allosteric Site Modulates Stress Parameters In vivo

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (51), p.18712-18717

2005

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Metabotropic glutamate receptor subtype 7 controls maternal care, maternal motivation and maternal aggression in mice

Genes, brain and behavior, 2020-01, Vol.19 (1), p.e12627-n/a

2020

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Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7

The European journal of neuroscience, 2003-06, Vol.17 (11), p.2409-2417

2003

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Metabotropic Glutamate Receptor Subtype 7 Ablation Causes Dysregulation of the HPA Axis and Increases Hippocampal BDNF Protein Levels: Implications for Stress-Related Psychiatric Disorders

Neuropsychopharmacology (New York, N.Y.), 2006-06, Vol.31 (6), p.1112-1122

2006

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Metabotropic Glutamate Receptor Subtypes as Targets for Neuroprotective Drugs

Journal of Cerebral Blood Flow & Metabolism, 2001-09, Vol.21 (9), p.1013-1033

2001

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Blocking Metabotropic Glutamate Receptor Subtype 7 via the Venus Flytrap Domain Promotes a Chronic Stress-Resilient Phenotype in Mice

Cells (Basel, Switzerland), 2022-06, Vol.11 (11), p.1817

2022

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Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain

Journal of medicinal chemistry, 2024-07, Vol.67 (14), p.11662-11687

2024

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Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

The Journal of neuroscience, 2001-11, Vol.21 (22), p.8734-8745

2001

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Individual differences in stress vulnerability: the role of gut pathobionts in stress-induced colitis

Brain, behavior, and immunity, 2017-08, Vol.64, p.23-32

2017

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Pharmacological modulation of metabotropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependent manner

Behavioural brain research, 2017-06, Vol.328, p.57-61

2017

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Differential effects of baclofen and oxytocin on the increased ethanol consumption following chronic psychosocial stress in mice

Addiction biology, 2013-01, Vol.18 (1), p.66-77

2013

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Relief from detrimental consequences of chronic psychosocial stress in mice deficient for the metabotropic glutamate receptor subtype 7

Neuropharmacology, 2017-03, Vol.115, p.139-148

2017

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Blocking metabotropic glutamate receptor subtype 5 relieves maladaptive chronic stress consequences

Brain, behavior, and immunity, 2017-01, Vol.59, p.79-92

2017

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Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling

Neuropharmacology, 2017-02, Vol.113, p.343-353

2017

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Differential roles of mGlu(7) and mGlu(8) in amygdala-dependent behavior and physiology

Neuropharmacology, 2013-09, Vol.72, p.215-223

2013

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Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse

Neuropharmacology, 2013-09, Vol.72, p.66-73

2013

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Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission

Behavioural pharmacology, 2008-09, Vol.19 (5-6), p.597

2008

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Neuroprotective activity of metabotropic glutamate receptor ligands

Advances in experimental medicine and biology, 2002, Vol.513, p.197

2002

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Orthosteric versus allosteric GPCR activation: The great challenge of group-III mGluRs

The Emerging Role of Metabotropic Glutamate Receptors in the Pathophysiology of Chronic Stress-Related Disorders

Metabotropic Glutamate Receptor Subtype 7 in the Bed Nucleus of the Stria Terminalis is Essential for Intermale Aggression

Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues

Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) via the Venus Flytrap Domain (VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior

Activation of the mGlu7 receptor elicits antidepressant-like effects in mice

Metabotropic glutamate receptor 7: At the interface of cognition and emotion

A Selective Metabotropic Glutamate Receptor 7 Agonist: Activation of Receptor Signaling via an Allosteric Site Modulates Stress Parameters In vivo

Metabotropic glutamate receptor subtype 7 controls maternal care, maternal motivation and maternal aggression in mice

Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7

Metabotropic Glutamate Receptor Subtype 7 Ablation Causes Dysregulation of the HPA Axis and Increases Hippocampal BDNF Protein Levels: Implications for Stress-Related Psychiatric Disorders

Metabotropic Glutamate Receptor Subtypes as Targets for Neuroprotective Drugs

Blocking Metabotropic Glutamate Receptor Subtype 7 via the Venus Flytrap Domain Promotes a Chronic Stress-Resilient Phenotype in Mice

Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain

Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

Individual differences in stress vulnerability: the role of gut pathobionts in stress-induced colitis

Pharmacological modulation of metabotropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependent manner

Differential effects of baclofen and oxytocin on the increased ethanol consumption following chronic psychosocial stress in mice

Relief from detrimental consequences of chronic psychosocial stress in mice deficient for the metabotropic glutamate receptor subtype 7

Blocking metabotropic glutamate receptor subtype 5 relieves maladaptive chronic stress consequences

Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling

Differential roles of mGlu(7) and mGlu(8) in amygdala-dependent behavior and physiology

Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse

Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission

Neuroprotective activity of metabotropic glutamate receptor ligands

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