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A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse

Biochemical pharmacology, 2002-01, Vol.63 (2), p.89-98

2002

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Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery

The Journal of pharmacology and experimental therapeutics, 2001-08, Vol.298 (2), p.395

2001

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The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L

Anticancer research, 1998-05, Vol.18 (3A), p.1527

1998

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Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes

Anti-cancer drugs, 2004-04, Vol.15 (4), p.389-399

2004

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High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed ( Nigella sativa L.)

Journal of pharmaceutical and biomedical analysis, 1999-04, Vol.19 (5), p.757-762

1999

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Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: Affinity for neuronal nicotinic acetylcholine receptors

Life sciences (1973), 2005-12, Vol.78 (5), p.495-505

2005

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QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release

Bioorganic & medicinal chemistry, 2006-05, Vol.14 (9), p.3017-3037

2006

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NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols

Cancer research (Chicago, Ill.), 2003-09, Vol.63 (17), p.5636-5645

2003

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Toxicity of Dipyridyl Compounds and Related Compounds

Critical reviews in toxicology, 2004-09, Vol.34 (5), p.447-460

2004

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Indirect Trapping of the Retroconjugate Addition Reaction Intermediate Involved in the Epimerization of Lobeline: Application to the Synthesis of (−)-Sedamine

Journal of organic chemistry, 2004-11, Vol.69 (24), p.8514-8517

2004

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In vitro/in vivo correlation of transdermal naltrexone prodrugs in hairless guinea pigs

Pharmaceutical research, 2005-06, Vol.22 (6), p.981-989

2005

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Effects of a lobelane analog on [11C]DTBZ binding to the VMAT2

NeuroImage (Orlando, Fla.), 2010-08, Vol.52 (S1), p.S68-S68

2010

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Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking

Biochemical pharmacology, 1997-10, Vol.54 (7), p.743-753

1997

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Physicochemical evaluation, in vitro human skin diffusion, and concurrent biotransformation of 3-O-alkyl carbonate prodrugs of naltrexone

Pharmaceutical research, 2004-07, Vol.21 (7), p.1146-1152

2004

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A pilot study of plasma caffeine concentrations in a US sample of smoker and nonsmoker volunteers

Progress in neuro-psychopharmacology & biological psychiatry, 2003-02, Vol.27 (1), p.165-171

2003

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Human Skin Permeation of Branched-Chain 3-O-Alkyl Ester and Carbonate Prodrugs of Naltrexone

Pharmaceutical research, 2005-05, Vol.22 (5), p.758-765

2005

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Novel antiglaucoma prodrugs and codrugs of ethacrynic acid

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (15), p.3524-3527

2005

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The Mechanism of l-Canavanine Cytotoxicity: Arginyl tRNA Synthetase as a Novel Target for Anticancer Drug Discovery

Journal of enzyme inhibition and medicinal chemistry, 2003-10, Vol.18 (5), p.383-394

2003

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A duplex “Gemini” prodrug of naltrexone for transdermal delivery

Journal of controlled release, 2004-06, Vol.97 (2), p.283-290

2004

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Transdermal Delivery of Naltrexone and its Active Metabolite 6-β-Naltrexol in Human Skin in Vitro and Guinea Pigs in Vivo

Journal of pharmaceutical sciences, 2005-09, Vol.94 (9), p.1965-1975

2005

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Synthesis and stability of two indomethacin prodrugs

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.1874-1879

2006

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Effect of pH on sublingual absorption of oxycodone hydrochloride

AAPS PharmSciTech, 2006-03, Vol.7 (1), p.E163-E167

2006

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Bioconversion of Naltrexone and Its 3-O-Alkyl-Ester Prodrugs in a Human Skin Equivalent

Journal of pharmaceutical sciences, 2005-04, Vol.94 (4), p.828-836

2005

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(Z)-2-(1-phenylsulfonyl-1 H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]-octan-3-one and (Z)-(S)-2-(1-phenyl-sulfonyl-1 h-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-ol

Acta crystallographica. Section C, Crystal structure communications, 2004-09, Vol.60 (Pt 9), p.o659-o661

2004

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Elimination of alkaloids from plant-derived human monoclonal antibody

Journal of immunological methods, 2004-03, Vol.286 (1), p.79-85

2004

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A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse

Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery

The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L

Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes

High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed ( Nigella sativa L.)

Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: Affinity for neuronal nicotinic acetylcholine receptors

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release

NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols

Toxicity of Dipyridyl Compounds and Related Compounds

Indirect Trapping of the Retroconjugate Addition Reaction Intermediate Involved in the Epimerization of Lobeline: Application to the Synthesis of (−)-Sedamine

In vitro/in vivo correlation of transdermal naltrexone prodrugs in hairless guinea pigs

Effects of a lobelane analog on [11C]DTBZ binding to the VMAT2

Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking

Physicochemical evaluation, in vitro human skin diffusion, and concurrent biotransformation of 3-O-alkyl carbonate prodrugs of naltrexone

A pilot study of plasma caffeine concentrations in a US sample of smoker and nonsmoker volunteers

Human Skin Permeation of Branched-Chain 3-O-Alkyl Ester and Carbonate Prodrugs of Naltrexone

Novel antiglaucoma prodrugs and codrugs of ethacrynic acid

The Mechanism of l-Canavanine Cytotoxicity: Arginyl tRNA Synthetase as a Novel Target for Anticancer Drug Discovery

A duplex “Gemini” prodrug of naltrexone for transdermal delivery

Transdermal Delivery of Naltrexone and its Active Metabolite 6-β-Naltrexol in Human Skin in Vitro and Guinea Pigs in Vivo

Synthesis and stability of two indomethacin prodrugs

Effect of pH on sublingual absorption of oxycodone hydrochloride

Bioconversion of Naltrexone and Its 3-O-Alkyl-Ester Prodrugs in a Human Skin Equivalent

(Z)-2-(1-phenylsulfonyl-1 H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]-octan-3-one and (Z)-(S)-2-(1-phenyl-sulfonyl-1 h-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-ol

Elimination of alkaloids from plant-derived human monoclonal antibody

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