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Disruption of Na+,HCO3― Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca2+ Sensitivity, and Hypertension Development in Mice

Circulation (New York, N.Y.), 2011-10, Vol.124 (17), p.1819-1829

2011

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Activation of Na+/H+ Exchanger 1 Is Sufficient to Generate Ca2+ Signals That Induce Cardiac Hypertrophy and Heart Failure

Circulation research, 2008-10, Vol.103 (8), p.891-899

2008

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Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains

Journal of neurochemistry, 2011-10, Vol.119 (1), p.124-135

2011

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Anti‐tumour/metastasis effects of the potassium‐sparing diuretic amiloride: An orally active anti‐cancer drug waiting for its call‐of‐duty?

International journal of cancer, 2011-11, Vol.129 (9), p.2051-2061

2011

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Nongenomic Effects of Cisplatin: Acute Inhibition of Mechanosensitive Transporters and Channels without Actin Remodeling

Cancer research (Chicago, Ill.), 2010-10, Vol.70 (19), p.7514-7522

2010

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An overview of inhibitors of Na +/H + exchanger

European Journal of Medicinal Chemistry, 2003-06, Vol.38 (6), p.547-554

2003

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Myocardial Protection at a Crossroads: The Need for Translation Into Clinical Therapy

Circulation research, 2004-07, Vol.95 (2), p.125-134

2004

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Reperfusion injury in humans : A review of clinical trials on reperfusion injury inhibitory strategies

Cardiovascular research, 2007-06, Vol.74 (3), p.343-355

2007

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NHERF-2 maintains endothelial homeostasis

Blood, 2012-05, Vol.119 (20), p.4798-4806

2012

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Na+/h+exchange inhibitors for cardioprotective therapy: progress, problems and prospects

Journal of the American College of Cardiology, 2002-03, Vol.39 (5), p.747-753

2002

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Expression and modulation of Na+/H+ exchanger 1 gene in hepatocellular carcinoma: A potential therapeutic target

Journal of gastroenterology and hepatology, 2011-02, Vol.26 (2), p.364-370

2011

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Effects of Na +/H + exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV–TAT peptide and octaarginine

Journal of controlled release, 2006-11, Vol.116 (2), p.247-254

2006

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Chronic inhibition of Na+/H+-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure

Cardiovascular research, 2005, Vol.65 (1), p.83-92

2005

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Chronic inhibition of the Na+/H+‐ exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling

British journal of pharmacology, 2008-07, Vol.154 (6), p.1266-1275

2008

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Blocking the Na+/H+ exchanger 1 with cariporide (HOE642) reduces the hypoxia-induced invasion of human tongue squamous cell carcinoma

International journal of oral and maxillofacial surgery, 2012-10, Vol.41 (10), p.1206-1210

2012

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Rapid decrease of intracellular pH associated with inhibition of Na+/H+ exchanger precedes apoptotic events in the MNK45 and MNK74 gastric cancer cell lines treated with 2-aminophenoxazine-3-one

Oncology reports, 2011-02, Vol.25 (2), p.341-346

2011

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Pharmacophore modeling, virtual screening and 3D-QSAR studies of 5-tetrahydroquinolinylidine aminoguanidine derivatives as sodium hydrogen exchanger inhibitors

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (11), p.3758-3765

2012

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Na+/H+ exchanger activity is increased in doxorubicin‐resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin

International journal of cancer, 2005-07, Vol.115 (6), p.924-929

2005

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Pharmacological possibilities for protection against myocardial reperfusion injury

Cardiovascular research, 2002-07, Vol.55 (1), p.25-37

2002

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Role of the cardiac Na+/H+ exchanger during ischemia and reperfusion

Cardiovascular research, 2003-03, Vol.57 (4), p.934-941

2003

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Mice With a Null Mutation in the NHE1 Na+-H+ Exchanger Are Resistant to Cardiac Ischemia-Reperfusion Injury

Circulation research, 2003-10, Vol.93 (8), p.776-782

2003

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Enhanced Na+ /H+ Exchange Activity Contributes to the Pathogenesis of Muscular Dystrophy via Involvement of P2 Receptors

The American journal of pathology, 2007-11, Vol.171 (5), p.1576-1587

2007

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Paclitaxel Induces Apoptosis via Protein Kinase A- and p38 Mitogen-activated Protein-dependent Inhibition of the Na+/H+ Exchanger (NHE) NHE Isoform 1 in Human Breast Cancer Cells

Clinical cancer research, 2003-06, Vol.9 (6), p.2366-2373

2003

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Cardioprotective effects of the Na+/H+ exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA

Circulation (New York, N.Y.), 2000-06, Vol.101 (25), p.2902-2908

2000

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Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits

Cardiovascular research, 2004-08, Vol.63 (2), p.273-282

2004

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Disruption of Na+,HCO3― Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca2+ Sensitivity, and Hypertension Development in Mice

Activation of Na+/H+ Exchanger 1 Is Sufficient to Generate Ca2+ Signals That Induce Cardiac Hypertrophy and Heart Failure

Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains

Anti‐tumour/metastasis effects of the potassium‐sparing diuretic amiloride: An orally active anti‐cancer drug waiting for its call‐of‐duty?

Nongenomic Effects of Cisplatin: Acute Inhibition of Mechanosensitive Transporters and Channels without Actin Remodeling

An overview of inhibitors of Na +/H + exchanger

Myocardial Protection at a Crossroads: The Need for Translation Into Clinical Therapy

Reperfusion injury in humans : A review of clinical trials on reperfusion injury inhibitory strategies

NHERF-2 maintains endothelial homeostasis

Na+/h+exchange inhibitors for cardioprotective therapy: progress, problems and prospects

Expression and modulation of Na+/H+ exchanger 1 gene in hepatocellular carcinoma: A potential therapeutic target

Effects of Na +/H + exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV–TAT peptide and octaarginine

Chronic inhibition of Na+/H+-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure

Chronic inhibition of the Na+/H+‐ exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling

Blocking the Na+/H+ exchanger 1 with cariporide (HOE642) reduces the hypoxia-induced invasion of human tongue squamous cell carcinoma

Rapid decrease of intracellular pH associated with inhibition of Na+/H+ exchanger precedes apoptotic events in the MNK45 and MNK74 gastric cancer cell lines treated with 2-aminophenoxazine-3-one

Pharmacophore modeling, virtual screening and 3D-QSAR studies of 5-tetrahydroquinolinylidine aminoguanidine derivatives as sodium hydrogen exchanger inhibitors

Na+/H+ exchanger activity is increased in doxorubicin‐resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin

Pharmacological possibilities for protection against myocardial reperfusion injury

Role of the cardiac Na+/H+ exchanger during ischemia and reperfusion

Mice With a Null Mutation in the NHE1 Na+-H+ Exchanger Are Resistant to Cardiac Ischemia-Reperfusion Injury

Enhanced Na+ /H+ Exchange Activity Contributes to the Pathogenesis of Muscular Dystrophy via Involvement of P2 Receptors

Paclitaxel Induces Apoptosis via Protein Kinase A- and p38 Mitogen-activated Protein-dependent Inhibition of the Na+/H+ Exchanger (NHE) NHE Isoform 1 in Human Breast Cancer Cells

Cardioprotective effects of the Na+/H+ exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA

Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits

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