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Virtual screening and in vitro experiments highlight cannabidiol as a drug‐like phosphodiesterase 9 inhibitor

The European journal of neuroscience, 2023-06, Vol.57 (12), p.1954-1965

2023

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Cannabidiol preferentially binds TRPV2: a novel mechanism of action

Neural regeneration research, 2022-12, Vol.17 (12), p.2693-2694

2022

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Ethanol neurotoxicity is mediated by changes in expression, surface localization and functional properties of glutamate AMPA receptors

Journal of neurochemistry, 2021-06, Vol.157 (6), p.2106-2118

2021

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Co-expression of the SARS-CoV-2 entry receptors ACE2 and TMPRSS2 in healthy human conjunctiva

Experimental eye research, 2021-04, Vol.205, p.108527-108527, Article 108527

2021

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A new ophthalmic formulation containing antiseptics and dexpanthenol: In vitro antimicrobial activity and effects on corneal and conjunctival epithelial cells

Experimental eye research, 2020-12, Vol.201, p.108269, Article 108269

2020

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Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation

International journal of pharmaceutics, 2020-06, Vol.583, p.119361, Article 119361

2020

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Using organotypic hippocampal slice cultures to gain insight into mechanisms responsible for the neuroprotective effects of meloxicam: a role for gamma aminobutyric and endoplasmic reticulum stress

Neural regeneration research, 2019-01, Vol.14 (1), p.65-66

2019

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The metaplastic effects of NMDA receptors blockade on reactivation of instrumental memories in rats

Neurobiology of learning and memory, 2018-10, Vol.154, p.87-96

2018

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Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-01, Vol.71 (1), p.50-60

2016

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Topiramate concentrations in neonates treated with prolonged whole body hypothermia for hypoxic ischemic encephalopathy

Epilepsia (Copenhagen), 2009-11, Vol.50 (11), p.2355-2361

2009

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Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3[beta] pathway in cultured cortical neurons and protects against neurotoxic insults

Journal of neurochemistry, 2009-09, Vol.110 (5), p.1469

2009

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Activation of the histaminergic H 3 receptor induces phosphorylation of the Akt/GSK‐3β pathway in cultured cortical neurons and protects against neurotoxic insults

Journal of neurochemistry, 2009-09, Vol.110 (5), p.1469-1478

2009

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Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death

The FEBS journal, 2009, Vol.276 (1), p.2-12

2009

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mGlu1α receptors are co-expressed with CB1 receptors in a subset of interneurons in the CA1 region of organotypic hippocampal slice cultures and adult rat brain

Neuropharmacology, 2008-09, Vol.55 (4), p.428-439

2008

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GAT-1 regulates both tonic and phasic GABAA receptor-mediated inhibition in the cerebral cortex

Journal of neurochemistry, 2008-06, Vol.105 (5), p.1781-1793

2008

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GAT-1 regulates both tonic and phasic GABA(A) receptor-mediated inhibition in the cerebral cortex

Journal of neurochemistry, 2008-06, Vol.105 (5), p.1781-1793

2008

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Neuroprotective Effects of Propofol in Models of Cerebral Ischemia

Anesthesiology (Philadelphia), 2006-01, Vol.104 (1), p.80-89

2006

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Group I metabotropic glutamate receptors stimulate the activity of poly(ADP-ribose) polymerase in mammalian mGlu1-transfected cells and in cortical cell cultures

Neuropharmacology, 2005, Vol.49, p.80-88

2005

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Neuroprotective effects of propofol in models of cerebral ischemia : Inhibition of mitochondrial swelling as a possible mechanism

Anesthesiology (Philadelphia), 2005, Vol.104 (1), p.80-89

2005

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Differential role of poly(ADP-ribose) polymerase-1 in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro

Molecular and cellular neuroscience, 2004-01, Vol.25 (1), p.172-180

2004

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Differential role of poly(ADP-ribose) polymerase-1in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro

Molecular and cellular neuroscience, 2004-01, Vol.25 (1), p.172-180

2004

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Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo

Pharmacology, biochemistry and behavior, 2002-09, Vol.73 (2), p.439-446

2002

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NeuroWatch

Neuroreport, 2002-03, Vol.13 (3), p.A49-A50

2002

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Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo: Metabotropic glutamate receptors

Pharmacology, biochemistry and behavior, 2002, Vol.73 (2), p.439-446

2002

Volltextzugriff (PDF)

ACETHYLCHOLINE: A DECOY GLIAL RECEPTOR SUPPRESSES SYNAPTIC TRANSMISSION

Neuroreport, 2001-10, Vol.12 (15), p.A87-A87

Pellegrini-Giampietro, Domenico E

2001

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Virtual screening and in vitro experiments highlight cannabidiol as a drug‐like phosphodiesterase 9 inhibitor

Cannabidiol preferentially binds TRPV2: a novel mechanism of action

Ethanol neurotoxicity is mediated by changes in expression, surface localization and functional properties of glutamate AMPA receptors

Co-expression of the SARS-CoV-2 entry receptors ACE2 and TMPRSS2 in healthy human conjunctiva

A new ophthalmic formulation containing antiseptics and dexpanthenol: In vitro antimicrobial activity and effects on corneal and conjunctival epithelial cells

Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation

Using organotypic hippocampal slice cultures to gain insight into mechanisms responsible for the neuroprotective effects of meloxicam: a role for gamma aminobutyric and endoplasmic reticulum stress

The metaplastic effects of NMDA receptors blockade on reactivation of instrumental memories in rats

Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models

Topiramate concentrations in neonates treated with prolonged whole body hypothermia for hypoxic ischemic encephalopathy

Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3[beta] pathway in cultured cortical neurons and protects against neurotoxic insults

Activation of the histaminergic H 3 receptor induces phosphorylation of the Akt/GSK‐3β pathway in cultured cortical neurons and protects against neurotoxic insults

Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death

mGlu1α receptors are co-expressed with CB1 receptors in a subset of interneurons in the CA1 region of organotypic hippocampal slice cultures and adult rat brain

GAT-1 regulates both tonic and phasic GABAA receptor-mediated inhibition in the cerebral cortex

GAT-1 regulates both tonic and phasic GABA(A) receptor-mediated inhibition in the cerebral cortex

Neuroprotective Effects of Propofol in Models of Cerebral Ischemia

Group I metabotropic glutamate receptors stimulate the activity of poly(ADP-ribose) polymerase in mammalian mGlu1-transfected cells and in cortical cell cultures

Neuroprotective effects of propofol in models of cerebral ischemia : Inhibition of mitochondrial swelling as a possible mechanism

Differential role of poly(ADP-ribose) polymerase-1 in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro

Differential role of poly(ADP-ribose) polymerase-1in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro

Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo

NeuroWatch

Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo: Metabotropic glutamate receptors

ACETHYLCHOLINE: A DECOY GLIAL RECEPTOR SUPPRESSES SYNAPTIC TRANSMISSION

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