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Perspective: TGR5 (Gpbar-1) in liver physiology and disease

Clinics and research in hepatology and gastroenterology, 2012-10, Vol.36 (5), p.412-419

2012

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Bile acid receptors in the biliary tree: TGR5 in physiology and disease

Biochimica et biophysica acta. Molecular basis of disease, 2018-04, Vol.1864 (4), p.1319-1325

2018

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The membrane-bound bile acid receptor TGR5 (Gpbar-1) is localized in the primary cilium of cholangiocytes

Biological chemistry, 2010-07, Vol.391 (7), p.785-789

2010

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Molecular analysis of cyst fluids improves the diagnostic accuracy of pre-operative assessment of pancreatic cystic lesions

Scientific reports, 2021-02, Vol.11 (1), p.2901-2901, Article 2901

2021

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The membrane‐bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders

Hepatology (Baltimore, Md.), 2009-09, Vol.50 (3), p.861-870

2009

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Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting

European journal of clinical microbiology & infectious diseases, 2021-05, Vol.40 (5), p.1063-1071

2021

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Endocrine and paracrine role of bile acids

World journal of gastroenterology : WJG, 2008-10, Vol.14 (37), p.5620-5629

Verena Keitel Ralf Kubitz Dieter Haussinger

2008

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TGR5: Pathogenetic Role and/or Therapeutic Target in Fibrosing Cholangitis?

Clinical reviews in allergy & immunology, 2015-06, Vol.48 (2-3), p.218-225

2015

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Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Hepatology (Baltimore, Md.), 2019-02, Vol.69 (2), p.666-683

2019

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Characterization of animal models for primary sclerosing cholangitis (PSC)

Journal of hepatology, 2014-06, Vol.60 (6), p.1290-1303

2014

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Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages

Journal of leukocyte biology, 2013-12, Vol.94 (6), p.1253-1264

2013

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Conjugated bilirubin triggers anemia by inducing erythrocyte death

Hepatology (Baltimore, Md.), 2015-01, Vol.61 (1), p.275-284

2015

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Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany

The Lancet regional health. Europe, 2021-09, Vol.8, p.100164-100164, Article 100164

2021

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Management of adults with Alagille syndrome

Hepatology international, 2023-10, Vol.17 (5), p.1098-1112

2023

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De Novo Bile Salt Transporter Antibodies as a Possible Cause of Recurrent Graft Failure After Liver Transplantation: a Novel Mechanism of Cholestasis

Hepatology (Baltimore, Md.), 2009-08, Vol.50 (2), p.510-517

2009

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Combined Mutations of Canalicular Transporter Proteins Cause Severe Intrahepatic Cholestasis of Pregnancy

Gastroenterology (New York, N.Y. 1943), 2006-08, Vol.131 (2), p.624-629

2006

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Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis

Journal of the American Society of Nephrology, 2018-11, Vol.29 (11), p.2658-2670

2018

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Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC)

BMC cancer, 2023-05, Vol.23 (1), p.470-470, Article 470

2023

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Extracellular Vesicles as Markers of Liver Function: Optimized Workflow for Biomarker Identification in Liver Disease

International journal of molecular sciences, 2023-06, Vol.24 (11), p.9631

2023

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Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020

Euro surveillance : bulletin européen sur les maladies transmissibles, 2020-06, Vol.25 (22), p.1

2020

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Molecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies

PLoS computational biology, 2016-02, Vol.12 (2), p.e1004693-e1004693

2016

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Enlarged extracellular vesicles are a negative prognostic factor in patients undergoing TACE for primary or secondary liver cancer-a case series

PloS one, 2021-08, Vol.16 (8), p.e0255983-e0255983

2021

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On the Mechanisms of Biliary Flux

Hepatology (Baltimore, Md.), 2021-12, Vol.74 (6), p.3497-3512

2021

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Bile-Based Cell-Free DNA Analysis Is a Reliable Diagnostic Tool in Pancreatobiliary Cancer

Cancers, 2020-12, Vol.13 (1), p.39

2020

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TGR5 in the Biliary Tree

Digestive diseases (Basel), 2011-01, Vol.29 (1), p.45-47

2011

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Perspective: TGR5 (Gpbar-1) in liver physiology and disease

Bile acid receptors in the biliary tree: TGR5 in physiology and disease

The membrane-bound bile acid receptor TGR5 (Gpbar-1) is localized in the primary cilium of cholangiocytes

Molecular analysis of cyst fluids improves the diagnostic accuracy of pre-operative assessment of pancreatic cystic lesions

The membrane‐bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders

Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting

Endocrine and paracrine role of bile acids

TGR5: Pathogenetic Role and/or Therapeutic Target in Fibrosing Cholangitis?

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Characterization of animal models for primary sclerosing cholangitis (PSC)

Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages

Conjugated bilirubin triggers anemia by inducing erythrocyte death

Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany

Management of adults with Alagille syndrome

De Novo Bile Salt Transporter Antibodies as a Possible Cause of Recurrent Graft Failure After Liver Transplantation: a Novel Mechanism of Cholestasis

Combined Mutations of Canalicular Transporter Proteins Cause Severe Intrahepatic Cholestasis of Pregnancy

Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis

Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC)

Extracellular Vesicles as Markers of Liver Function: Optimized Workflow for Biomarker Identification in Liver Disease

Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020

Molecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies

Enlarged extracellular vesicles are a negative prognostic factor in patients undergoing TACE for primary or secondary liver cancer-a case series

On the Mechanisms of Biliary Flux

Bile-Based Cell-Free DNA Analysis Is a Reliable Diagnostic Tool in Pancreatobiliary Cancer

TGR5 in the Biliary Tree

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