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Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain

Journal of lipid research, 2022-08, Vol.63 (8), p.100249-100249, Article 100249

2022

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Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

The Journal of neuroscience, 2007-10, Vol.27 (40), p.10695-10702

2007

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Immune system gene dysregulation in autism and schizophrenia

Developmental neurobiology (Hoboken, N.J.), 2012-10, Vol.72 (10), p.1277-1287

2012

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Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic-ischemic injury

Pediatric research, 2022-01, Vol.91 (1), p.92-100

2022

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Vulnerability of DHCR7+/− mutation carriers to aripiprazole and trazodone exposure

Journal of lipid research, 2017-11, Vol.58 (11), p.2139-2146

2017

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Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

Annals of neurology, 2006-03, Vol.59 (3), p.478-489

2006

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Chemical Inhibition of Sterol Biosynthesis

Biomolecules (Basel, Switzerland), 2024-04, Vol.14 (4), p.410

2024

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The Effect of Small Molecules on Sterol Homeostasis: Measuring 7‑Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

Journal of medicinal chemistry, 2016-02, Vol.59 (3), p.1102-1115

2016

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Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Toxicology and applied pharmacology, 2018-06, Vol.349, p.21-28

2018

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Early Brain microRNA/mRNA Expression is Region-Specific After Neonatal Hypoxic-Ischemic Injury in a Mouse Model

Frontiers in genetics, 2022-02, Vol.13, p.841043-841043

2022

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Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice

Biomolecules (Basel, Switzerland), 2022-10, Vol.12 (10), p.1535

2022

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DHCEO accumulation is a critical mediator of pathophysiology in a Smith–Lemli–Opitz syndrome model

Neurobiology of disease, 2012-03, Vol.45 (3), p.923-929

2012

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Disruption of cerebral cortex MET signaling in autism spectrum disorder

Annals of neurology, 2007-09, Vol.62 (3), p.243-250

2007

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Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells[S]

Journal of lipid research, 2013-04, Vol.54 (4), p.1135-1143

2013

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Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis

Biomolecules (Basel, Switzerland), 2023-08, Vol.13 (9), p.1321

2023

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An altered peripheral IL6 response in major depressive disorder

Neurobiology of disease, 2016-05, Vol.89, p.46-54

2016

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Expressing the mind

Neurobiology of disease, 2012-01, Vol.45 (1), p.1-2

2012

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Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

The Journal of neuroscience, 2002-04, Vol.22 (7), p.2718-2729

2002

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Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

Trends in Neurosciences, 2001-08, Vol.24 (8), p.479-486

2001

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Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

Nature communications, 2016-09, Vol.7 (1), p.12743-12743, Article 12743

2016

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Synaptic changes in the brain of subjects with schizophrenia

International journal of developmental neuroscience, 2011-05, Vol.29 (3), p.305-309

2011

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Cholesterol Biosynthesis and Uptake in Developing Neurons

ACS chemical neuroscience, 2019-08, Vol.10 (8), p.3671-3681

2019

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Ubiquitous Aberration in Cholesterol Metabolism across Pancreatic Ductal Adenocarcinoma

Metabolites, 2022-01, Vol.12 (1), p.47

2022

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Immune transcriptome alterations in the temporal cortex of subjects with autism

Neurobiology of disease, 2008-06, Vol.30 (3), p.303-311

2008

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Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia

Journal of neuroinflammation, 2014-11, Vol.11 (1), p.183-183, Article 183

2014

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Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain

Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

Immune system gene dysregulation in autism and schizophrenia

Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic-ischemic injury

Vulnerability of DHCR7+/− mutation carriers to aripiprazole and trazodone exposure

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

Chemical Inhibition of Sterol Biosynthesis

The Effect of Small Molecules on Sterol Homeostasis: Measuring 7‑Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Early Brain microRNA/mRNA Expression is Region-Specific After Neonatal Hypoxic-Ischemic Injury in a Mouse Model

Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice

DHCEO accumulation is a critical mediator of pathophysiology in a Smith–Lemli–Opitz syndrome model

Disruption of cerebral cortex MET signaling in autism spectrum disorder

Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells[S]

Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis

An altered peripheral IL6 response in major depressive disorder

Expressing the mind

Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

Synaptic changes in the brain of subjects with schizophrenia

Cholesterol Biosynthesis and Uptake in Developing Neurons

Ubiquitous Aberration in Cholesterol Metabolism across Pancreatic Ductal Adenocarcinoma

Immune transcriptome alterations in the temporal cortex of subjects with autism

Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia

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