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Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

The Journal of clinical investigation, 2003-11, Vol.112 (9), p.1300-1307

2003

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Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

The Journal of clinical investigation, 2003-11, Vol.112 (9), p.1300-1307

2003

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Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator

The Journal of pharmacology and experimental therapeutics, 2014-09, Vol.350 (3), p.589

2014

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Computer-Aided Identification of Recognized Drugs as Pseudomonas aeruginosa Quorum-Sensing Inhibitors

Antimicrobial Agents and Chemotherapy, 2009-06, Vol.53 (6), p.2432-2443

2009

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Azithromycin Blocks Quorum Sensing and Alginate Polymer Formation and Increases the Sensitivity to Serum and Stationary-Growth-Phase Killing of Pseudomonas aeruginosa and Attenuates Chronic P. aeruginosa Lung Infection in Cftr−/− Mice

Antimicrobial Agents and Chemotherapy, 2007-10, Vol.51 (10), p.3677-3687

2007

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The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional

Molecular microbiology, 2006-12, Vol.62 (5), p.1264-1277

2006

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Screening for Quorum-Sensing Inhibitors (QSI) by Use of a Novel Genetic System, the QSI Selector

Journal of Bacteriology, 2005-03, Vol.187 (5), p.1799-1814

2005

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Quantification of biofilm structures by the novel computer program COMSTAT

Microbiology (Society for General Microbiology), 2000-10, Vol.146 ( Pt 10), p.2395

2000

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Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production

Antimicrobial Agents and Chemotherapy, 2004-04, Vol.48 (4), p.1175-1187

2004

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Alginate Overproduction Affects Pseudomonas aeruginosa Biofilm Structure and Function

Journal of Bacteriology, 2001-09, Vol.183 (18), p.5395-5401

2001

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High-throughput screening of antagonists for the orphan G-protein coupled receptor GPR139

Acta pharmacologica Sinica, 2015-07, Vol.36 (7), p.874-878

2015

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N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

Microbiology (Society for General Microbiology), 2001-12, Vol.147 (Pt 12), p.3249

2001

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Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis

Infection and Immunity, 2005-04, Vol.73 (4), p.2504-2514

2005

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Dynamics and Spatial Distribution of β-Lactamase Expression in Pseudomonas aeruginosa Biofilms

Antimicrobial Agents and Chemotherapy, 2004-04, Vol.48 (4), p.1168-1174

2004

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Phosphorus Limitation Enhances Biofilm Formation of the Plant Pathogen Agrobacterium tumefaciens through the PhoR-PhoB Regulatory System

Journal of Bacteriology, 2004-07, Vol.186 (14), p.4492-4501

2004

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gfp-Based N-Acyl Homoserine-Lactone Sensor Systems for Detection of Bacterial Communication

Applied and Environmental Microbiology, 2001-02, Vol.67 (2), p.575-585

2001

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A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm

Environmental microbiology, 2000-10, Vol.2 (5), p.530-541

2000

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Constitutive High Expression of Chromosomal β-Lactamase in Pseudomonas aeruginosa Caused by a New Insertion Sequence (IS1669) Located in ampD

Antimicrobial Agents and Chemotherapy, 2002-11, Vol.46 (11), p.3406-3411

2002

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Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139

ACS medicinal chemistry letters, 2011-04, Vol.2 (4), p.303-306

2011

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Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

The EMBO journal, 2003-08, Vol.22 (15), p.3803-3815

2003

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Design and Synthesis of Pyrrolo[2,3‑d]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate

Journal of medicinal chemistry, 2021-07, Vol.64 (14), p.10312-10332

2021

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Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2022-07, Vol.130 (7), p.458-476

2022

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Abnormal visual gain control in a Parkinson's disease model

Human molecular genetics, 2014-09, Vol.23 (17), p.4465-4478

2014

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Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

Journal of medicinal chemistry, 2017-11, Vol.60 (21), p.8945-8962

2017

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The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility

Microbiology (Society for General Microbiology), 2001-09, Vol.147 (Pt 9), p.2517

2001

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Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator

Computer-Aided Identification of Recognized Drugs as Pseudomonas aeruginosa Quorum-Sensing Inhibitors

Azithromycin Blocks Quorum Sensing and Alginate Polymer Formation and Increases the Sensitivity to Serum and Stationary-Growth-Phase Killing of Pseudomonas aeruginosa and Attenuates Chronic P. aeruginosa Lung Infection in Cftr−/− Mice

The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional

Screening for Quorum-Sensing Inhibitors (QSI) by Use of a Novel Genetic System, the QSI Selector

Quantification of biofilm structures by the novel computer program COMSTAT

Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production

Alginate Overproduction Affects Pseudomonas aeruginosa Biofilm Structure and Function

High-throughput screening of antagonists for the orphan G-protein coupled receptor GPR139

N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis

Dynamics and Spatial Distribution of β-Lactamase Expression in Pseudomonas aeruginosa Biofilms

Phosphorus Limitation Enhances Biofilm Formation of the Plant Pathogen Agrobacterium tumefaciens through the PhoR-PhoB Regulatory System

gfp-Based N-Acyl Homoserine-Lactone Sensor Systems for Detection of Bacterial Communication

A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm

Constitutive High Expression of Chromosomal β-Lactamase in Pseudomonas aeruginosa Caused by a New Insertion Sequence (IS1669) Located in ampD

Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139

Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

Design and Synthesis of Pyrrolo[2,3‑d]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate

Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

Abnormal visual gain control in a Parkinson's disease model

Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility

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