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Current and Emerging Cell Culture Manufacturing Technologies for Influenza Vaccines

BioMed research international, 2015-01, Vol.2015 (2015), p.1-11

2015

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Production of Lentiviral Vectors Using a HEK-293 Producer Cell Line and Advanced Perfusion Processing

Frontiers in bioengineering and biotechnology, 2022-06, Vol.10, p.887716-887716

2022

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Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery

Journal of virological methods, 2014-02, Vol.196, p.163-173

2014

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Vero cell upstream bioprocess development for the production of viral vectors and vaccines

Biotechnology advances, 2020-11, Vol.44, p.107608-14, Article 107608

2020

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Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine

Viruses, 2024-06, Vol.16 (6), p.942

2024

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A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms

Scientific reports, 2020-07, Vol.10 (1), p.12166-12166, Article 12166

2020

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Targeted Delivery of Chimeric Antigen Receptor into T Cells via CRISPR-Mediated Homology-Directed Repair with a Dual-AAV6 Transduction System

Current issues in molecular biology, 2023-09, Vol.45 (10), p.7705-7720

2023

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Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing

Vaccine, 2010-05, Vol.28 (21), p.3661-3671

2010

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Intensified Influenza Virus Production in Suspension HEK293SF Cell Cultures Operated in Fed-Batch or Perfusion with Continuous Harvest

Vaccines (Basel), 2023-12, Vol.11 (12), p.1819

2023

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Bioprocessing of baculovirus vectors: a review

Current gene therapy, 2010-06, Vol.10 (3), p.174-186

2010

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Achieving High-Yield Production of Functional AAV5 Gene Delivery Vectors via Fedbatch in an Insect Cell-One Baculovirus System

Molecular therapy. Methods & clinical development, 2019-06, Vol.13, p.279-289

2019

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Rapid High-Yield Production of Functional SARS-CoV-2 Receptor Binding Domain by Viral and Non-Viral Transient Expression for Pre-Clinical Evaluation

Vaccines (Basel), 2020-11, Vol.8 (4), p.654

2020

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Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza

PloS one, 2017-06, Vol.12 (6), p.e0180314-e0180314

2017

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Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells

Biotechnology journal, 2016-02, Vol.11 (2), p.290-297

2016

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Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture

BMC biotechnology, 2011-09, Vol.11 (1), p.84-84, Article 84

2011

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Particle quantification of influenza viruses by high performance liquid chromatography

Vaccine, 2015-01, Vol.33 (1), p.78-84

2015

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Intranasally Delivered Adenoviral Vector Protects Chickens against Newcastle Disease Virus: Vaccine Manufacturing and Stability Assessments for Liquid and Lyophilized Formulations

Vaccines (Basel), 2023-12, Vol.12 (1), p.41

2023

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Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography

Molecular therapy. Methods & clinical development, 2020-09, Vol.18, p.803-810

2020

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Haplotype-resolved de novo assembly of the Vero cell line genome

npj vaccines, 2021-08, Vol.6 (1), p.106-106, Article 106

2021

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Titration methods for rVSV-based vaccine manufacturing

MethodsX, 2020-01, Vol.7, p.100806-100806, Article 100806

2020

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Fed-batch strategies for intensified rVSV vector production in high cell density cultures of suspension HEK293 cells

Biotechnology progress, 2024-09, p.e3506

2024

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Only a small fraction of cells produce assembled capsids during transfection‐based manufacturing of adeno‐associated virus vectors

Biotechnology and bioengineering, 2022-06, Vol.119 (6), p.1685-1690

2022

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Recombinant Protein Production in Large-Scale Agitated Bioreactors Using the Baculovirus Expression Vector System

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1350, p.241

2016

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Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics

Critical reviews in biotechnology, 2018-08, Vol.38 (6), p.918-940

2018

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Large-Scale Transient Transfection of Suspension Mammalian Cells for VLP Production

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1674, p.117

2018

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Current and Emerging Cell Culture Manufacturing Technologies for Influenza Vaccines

Production of Lentiviral Vectors Using a HEK-293 Producer Cell Line and Advanced Perfusion Processing

Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery

Vero cell upstream bioprocess development for the production of viral vectors and vaccines

Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine

A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms

Targeted Delivery of Chimeric Antigen Receptor into T Cells via CRISPR-Mediated Homology-Directed Repair with a Dual-AAV6 Transduction System

Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing

Intensified Influenza Virus Production in Suspension HEK293SF Cell Cultures Operated in Fed-Batch or Perfusion with Continuous Harvest

Bioprocessing of baculovirus vectors: a review

Achieving High-Yield Production of Functional AAV5 Gene Delivery Vectors via Fedbatch in an Insect Cell-One Baculovirus System

Rapid High-Yield Production of Functional SARS-CoV-2 Receptor Binding Domain by Viral and Non-Viral Transient Expression for Pre-Clinical Evaluation

Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza

Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells

Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture

Particle quantification of influenza viruses by high performance liquid chromatography

Intranasally Delivered Adenoviral Vector Protects Chickens against Newcastle Disease Virus: Vaccine Manufacturing and Stability Assessments for Liquid and Lyophilized Formulations

Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography

Haplotype-resolved de novo assembly of the Vero cell line genome

Titration methods for rVSV-based vaccine manufacturing

Fed-batch strategies for intensified rVSV vector production in high cell density cultures of suspension HEK293 cells

Only a small fraction of cells produce assembled capsids during transfection‐based manufacturing of adeno‐associated virus vectors

Recombinant Protein Production in Large-Scale Agitated Bioreactors Using the Baculovirus Expression Vector System

Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics

Large-Scale Transient Transfection of Suspension Mammalian Cells for VLP Production

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