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An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Angewandte Chemie International Edition, 2020-08, Vol.59 (32), p.13496-13501

International ed. in English, 2020

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Acyl azide modification of the ubiquitin C-terminus enables DUB capture

Chemical communications (Cambridge, England), 2023-01, Vol.59 (1), p.1333-1336

2023

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The Ubiquitin Enigma: Progress in the Detection and Chemical Synthesis of Branched Ubiquitin Chains

Chembiochem : a European journal of chemical biology, 2020-12, Vol.21 (23), p.3313-3318

2020

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Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones

Journal of the American Chemical Society, 2019-02, Vol.141 (8), p.3654-3663

2019

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The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1

Chemical science (Cambridge), 2023-05, Vol.14 (21), p.5681-5688

2023

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One-Pot Synthesis of a Bis-Thio-Acetone Linked Ubiquitinated Histones Using 1,3-Dibromoacetone

Journal of organic chemistry, 2020-12, Vol.85 (23), p.15631-15637

2020

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Efficient Semi‐Synthesis of Atypical Ubiquitin Chains and Ubiquitin‐Based Probes Forged by Thioether Isopeptide Bonds

Chemistry : a European journal, 2019-12, Vol.25 (72), p.16668-16675

2019

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Cell-Permeable Stimuli-Responsive Ubiquitin Probe for Time-Resolved Monitoring of Substrate Ubiquitination in Live Cells

JACS Au, 2023-10, Vol.3 (10), p.2873-2882

2023

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Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes

Journal of the American Chemical Society, 2022-10, Vol.144 (40), p.18329-18337

2022

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Chemical synthesis of on demand-activated SUMO-based probe by a photocaged glycine-assisted strategy

Bioorganic & medicinal chemistry letters, 2023-10, Vol.94, p.129460-129460, Article 129460

2023

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Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

Nature structural & molecular biology, 2024-02, Vol.31 (2), p.300-310

2024

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An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Angewandte Chemie, 2020-08, Vol.132 (32), p.13598-13603

2020

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Semi-synthesis of K27-linked-mixed-triubiquitin chains through a combination of enzymatic reaction with CAACU strategy

Tetrahedron letters, 2021-05, Vol.71, p.153000, Article 153000

2021

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The Study of the Chemical Synthesis and Preparation of Histone with Post- Translational Modifications

Current organic synthesis, 2015-01, Vol.12 (2), p.150-162

2015

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Acid-sensitive auxiliary assisted atypical diubiquitin synthesis exploiting thiol-ene coupling

Tetrahedron letters, 2019-10, Vol.60 (41), p.151123, Article 151123

2019

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Efficient semi-synthesis of ubiquitin-7-amino-4-methylcoumarin

Tetrahedron, 2018-07, Vol.74 (28), p.3931-3935

2018

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Efficient chemical synthesis for the analogue of ubiquitin-based probe Ub–AMC with native bioactivity

RSC advances, 2016-01, Vol.6 (53), p.47926-47930

2016

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Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally defined K63-Polyubiquitylated Linker Histone H1

Angewandte Chemie International Edition, 2024-10, p.e202413651

2024

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Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16

Nature structural & molecular biology, 2024-06

2024

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Methods of the enzymatic production of Ub-based tools

Current research in chemical biology, 2023, Vol.3, p.100044, Article 100044

2023

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Promotion of RNF168‐Mediated Nucleosomal H2A Ubiquitylation by Structurally defined K63‐Polyubiquitylated Linker Histone H1

Angewandte Chemie, 2024-10

2024

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Catalyst free hydrazone ligation for protein labeling and modification using electron-deficient benzaldehyde reagentsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ob01810c

2018-10

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Efficient chemical synthesis for the analogue of ubiquitin-based probe Ub-AMC with native bioactivityElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra11019c

2016-05

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Degradation behaviors of surface modified magnesium alloy wires in different simulated physiological environments

Frontiers of materials science, 2014-09, Vol.8 (3), p.281-294

2014

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Ferricyanide-Promoted Oxidative Activation and Ligation of Protein Thioacids in Neutral Aqueous Media

CCS Chemistry, 2024-08, Vol.6 (8), p.2031-2043

2024

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An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Acyl azide modification of the ubiquitin C-terminus enables DUB capture

The Ubiquitin Enigma: Progress in the Detection and Chemical Synthesis of Branched Ubiquitin Chains

Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones

The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1

One-Pot Synthesis of a Bis-Thio-Acetone Linked Ubiquitinated Histones Using 1,3-Dibromoacetone

Efficient Semi‐Synthesis of Atypical Ubiquitin Chains and Ubiquitin‐Based Probes Forged by Thioether Isopeptide Bonds

Cell-Permeable Stimuli-Responsive Ubiquitin Probe for Time-Resolved Monitoring of Substrate Ubiquitination in Live Cells

Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes

Chemical synthesis of on demand-activated SUMO-based probe by a photocaged glycine-assisted strategy

Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

An E1‐Catalyzed Chemoenzymatic Strategy to Isopeptide‐N‐Ethylated Deubiquitylase‐Resistant Ubiquitin Probes

Semi-synthesis of K27-linked-mixed-triubiquitin chains through a combination of enzymatic reaction with CAACU strategy

The Study of the Chemical Synthesis and Preparation of Histone with Post- Translational Modifications

Acid-sensitive auxiliary assisted atypical diubiquitin synthesis exploiting thiol-ene coupling

Efficient semi-synthesis of ubiquitin-7-amino-4-methylcoumarin

Efficient chemical synthesis for the analogue of ubiquitin-based probe Ub–AMC with native bioactivity

Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally defined K63-Polyubiquitylated Linker Histone H1

Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16

Methods of the enzymatic production of Ub-based tools

Promotion of RNF168‐Mediated Nucleosomal H2A Ubiquitylation by Structurally defined K63‐Polyubiquitylated Linker Histone H1

Catalyst free hydrazone ligation for protein labeling and modification using electron-deficient benzaldehyde reagentsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ob01810c

Efficient chemical synthesis for the analogue of ubiquitin-based probe Ub-AMC with native bioactivityElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra11019c

Degradation behaviors of surface modified magnesium alloy wires in different simulated physiological environments

Ferricyanide-Promoted Oxidative Activation and Ligation of Protein Thioacids in Neutral Aqueous Media

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