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Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

The Journal of neuroscience, 2008-11, Vol.28 (45), p.11500-11510

2008

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Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

Human molecular genetics, 2008-12, Vol.17 (23), p.3767-3775

2008

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SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

Cell reports (Cambridge), 2013-07, Vol.4 (2), p.362-375

2013

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The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis

Human molecular genetics, 2007-01, Vol.16 (1), p.61-77

2007

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Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila

Experimental neurology, 2021-04, Vol.338, p.113463, Article 113463

2021

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Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

Journal of cell science, 2022-01, Vol.135 (2)

2022

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Phosphorylation of Threonine 3: IMPLICATIONS FOR HUNTINGTIN AGGREGATION AND NEUROTOXICITY

The Journal of biological chemistry, 2009-10, Vol.284 (43), p.29427-29436

2009

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Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Journal of Huntington's disease, 2022-01, Vol.11 (1), p.25

2022

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Autophagy researchers

Autophagy, 2014-02, Vol.10 (2), p.188-191

2014

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Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice

Journal of Huntington's disease, 2012, Vol.1 (1), p.71

2012

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Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases

Expert opinion on therapeutic targets, 2003-04, Vol.7 (2), p.201-213

2003

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RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I

The Journal of biological chemistry, 1996-08, Vol.271 (35), p.21062-21067

1996

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Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Biochemistry (Easton), 1988-11, Vol.27 (22), p.8393-8400

1988

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Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Molecular and Cellular Biology, 1998-07, Vol.18 (7), p.3752-3761

1998

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Expression and Function of a Mislocalized Form of Peroxisomal Malate Dehydrogenase (MDH3) in Yeast (∗)

The Journal of biological chemistry, 1995-09, Vol.270 (36), p.21220-21225

1995

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The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor

Genes & development, 1996-10, Vol.10 (20), p.2551-2563

1996

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Isolation and characterization of the yeast gene encoding the MDH3 isozyme of malate dehydrogenase

The Journal of biological chemistry, 1992-12, Vol.267 (34), p.24708-24715

1992

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RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae

Genes & development, 1994-10, Vol.8 (19), p.2349-2362

1994

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Expression and function of heterologous forms of malate dehydrogenase in yeast

Archives of biochemistry and biophysics, 1992-02, Vol.293 (1), p.93-102

1992

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Habitat fragmentation causes immediate and time-delayed biodiversity loss at different trophic levels

Ecology letters, 2010-05, Vol.13 (5), p.597-605

2010

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Treating the whole body in Huntington's disease

Lancet neurology, 2015-11, Vol.14 (11), p.1135-1142

2015

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Extinction debt: a challenge for biodiversity conservation

Trends in ecology & evolution (Amsterdam), 2009-10, Vol.24 (10), p.564-571

2009

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Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment

Genomics (San Diego, Calif.), 2013-09, Vol.102 (3), p.157-162

2013

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Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis

Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice

Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila

Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

Phosphorylation of Threonine 3: IMPLICATIONS FOR HUNTINGTIN AGGREGATION AND NEUROTOXICITY

Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Autophagy researchers

Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice

Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases

RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I

Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Expression and Function of a Mislocalized Form of Peroxisomal Malate Dehydrogenase (MDH3) in Yeast (∗)

The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor

Isolation and characterization of the yeast gene encoding the MDH3 isozyme of malate dehydrogenase

RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae

Expression and function of heterologous forms of malate dehydrogenase in yeast

Habitat fragmentation causes immediate and time-delayed biodiversity loss at different trophic levels

Treating the whole body in Huntington's disease

Extinction debt: a challenge for biodiversity conservation

Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment

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