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Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours

ESMO open, 2020-12, Vol.5 (6), p.e001081, Article e001081

2020

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Interaction between the Amino- and Carboxyl-terminal Regions of the Rat Androgen Receptor Modulates Transcriptional Activity and Is Influenced by Nuclear Receptor Coactivators

The Journal of biological chemistry, 1997-11, Vol.272 (47), p.29821-29828

1997

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Real-world assessment of AR-LBD mutations in metastatic castration-resistant prostate cancer

Journal of clinical oncology, 2023-02, Vol.41 (6_suppl), p.204-204

2023

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Mutual Transcriptional Interference between RelA and Androgen Receptor

The Journal of biological chemistry, 1996-09, Vol.271 (39), p.24151-24156

1996

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Impact of activating androgen receptor (AR) mutations on AR sensitivity to alternative ligands and response to ODM-208, a selective, first-in-class CYP11A1 inhibitor, in patients with advanced metastatic castration-resistant prostate cancer (mCRPC)

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.5057-5057

2022

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MK-5684 (ODM-208), a CYP11A1 inhibitor, in patients with metastatic castration-resistant prostate cancer (mCRPC) with and without AR-LBD mutations: CYPIDES phase 2 results

Journal of clinical oncology, 2024-02, Vol.42 (4_suppl), p.159-159

2024

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Phase 1 results of the ODM-208 first-in-human phase 1-2 trial in patients with metastatic castration-resistant prostate cancer (CYPIDES)

Journal of clinical oncology, 2022-02, Vol.40 (6_suppl), p.18-18

2022

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28 Days Without - a new approach to nicotine dependence treatment in Finland

Tobacco prevention & cessation, 2018-06, Vol.4 (Supplement)

2018

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ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity

Molecular cancer therapeutics, 2019-01, Vol.18 (1), p.28-38

2019

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Prevalence and Spectrum of AR Ligand-Binding Domain Mutations Detected in Circulating-Tumor DNA Across Disease States in Men With Metastatic Castration-Resistant Prostate Cancer

JCO precision oncology, 2024-05, Vol.8 (8), p.e2300330

2024

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Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1753-1753

2020

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Abstract 4649: ODM-207, a novel BET-bromodomain inhibitor as a therapeutic approach for the treatment of prostate and breast cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4649-4649

2016

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Abstract 118: Targeting cancer with a novel BET bromodomain inhibitor ODM-207

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.118-118

2017

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Targeted Inhibition of CYP11A1 in Castration-Resistant Prostate Cancer

NEJM evidence, 2024-01, Vol.3 (1), p.EVIDoa2300171

2024

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Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy

Bioorganic & medicinal chemistry, 2014-06, Vol.22 (12), p.3187-3203

2014

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CHEK2 mutations in primary glioblastomas

Journal of neuro-oncology, 2005-08, Vol.74 (1), p.93-95

2005

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Stimulation of androgen-regulated transactivation by modulators of protein phosphorylation

Endocrinology (Philadelphia), 1994-10, Vol.135 (4), p.1359

1994

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242: Profiling Multigenetic Variation in Androgen Pathway as a Risk Factor for Prostate Cancer

The Journal of urology, 2005-04, Vol.173 (4), p.66-67

2005

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408: CHEK2 and MSR1 Genes in Prostate Cancer Predisposition in Finnish Population

The Journal of urology, 2004-04, Vol.171 (4), p.108-108

2004

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Dominant negative regulation of trans-activation by the rat androgen receptor : roles of the N-terminal domain and heterodimer formation

Molecular endocrinology (Baltimore, Md.), 1993-11, Vol.7 (11), p.1399-1407

1993

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Induction of UDP-glycosyltransferase family 1 genes in rat liver: different patterns of mRNA expression with two inducers, 3-methylcholanthrene and β-naphthoflavone

Biochemical pharmacology, 1998-09, Vol.56 (5), p.569-575

1998

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ELAC2/HPC2 involvement in hereditary and sporadic prostate cancer1

Cancer research (Chicago, Ill.), 2001, Vol.61 (16), p.6038-6041

2001

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Incidence Trends for SARS-CoV-2 Alpha and Beta Variants, Finland, Spring 2021

Emerging infectious diseases, 2021-12, Vol.27 (12), p.3137-3141

2021

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Homeostatic response to sleep/rest deprivation by constant water flow in larval zebrafish in both dark and light conditions

Journal of sleep research, 2017-06, Vol.26 (3), p.394-400

2017

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Avian Influenza outbreaks: Human infection risks for beach users - One health concern and environmental surveillance implications

The Science of the total environment, 2024-09, Vol.943, p.173692, Article 173692

2024

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Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours

Interaction between the Amino- and Carboxyl-terminal Regions of the Rat Androgen Receptor Modulates Transcriptional Activity and Is Influenced by Nuclear Receptor Coactivators

Real-world assessment of AR-LBD mutations in metastatic castration-resistant prostate cancer

Mutual Transcriptional Interference between RelA and Androgen Receptor

Impact of activating androgen receptor (AR) mutations on AR sensitivity to alternative ligands and response to ODM-208, a selective, first-in-class CYP11A1 inhibitor, in patients with advanced metastatic castration-resistant prostate cancer (mCRPC)

MK-5684 (ODM-208), a CYP11A1 inhibitor, in patients with metastatic castration-resistant prostate cancer (mCRPC) with and without AR-LBD mutations: CYPIDES phase 2 results

Phase 1 results of the ODM-208 first-in-human phase 1-2 trial in patients with metastatic castration-resistant prostate cancer (CYPIDES)

28 Days Without - a new approach to nicotine dependence treatment in Finland

ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity

Prevalence and Spectrum of AR Ligand-Binding Domain Mutations Detected in Circulating-Tumor DNA Across Disease States in Men With Metastatic Castration-Resistant Prostate Cancer

Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors

Abstract 4649: ODM-207, a novel BET-bromodomain inhibitor as a therapeutic approach for the treatment of prostate and breast cancer

Abstract 118: Targeting cancer with a novel BET bromodomain inhibitor ODM-207

Targeted Inhibition of CYP11A1 in Castration-Resistant Prostate Cancer

Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy

CHEK2 mutations in primary glioblastomas

Stimulation of androgen-regulated transactivation by modulators of protein phosphorylation

242: Profiling Multigenetic Variation in Androgen Pathway as a Risk Factor for Prostate Cancer

408: CHEK2 and MSR1 Genes in Prostate Cancer Predisposition in Finnish Population

Dominant negative regulation of trans-activation by the rat androgen receptor : roles of the N-terminal domain and heterodimer formation

Induction of UDP-glycosyltransferase family 1 genes in rat liver: different patterns of mRNA expression with two inducers, 3-methylcholanthrene and β-naphthoflavone

ELAC2/HPC2 involvement in hereditary and sporadic prostate cancer1

Incidence Trends for SARS-CoV-2 Alpha and Beta Variants, Finland, Spring 2021

Homeostatic response to sleep/rest deprivation by constant water flow in larval zebrafish in both dark and light conditions

Avian Influenza outbreaks: Human infection risks for beach users - One health concern and environmental surveillance implications

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