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Slowing Progression of Cardiovascular Calcification With SNF472 in Patients on Hemodialysis: Results of a Randomized Phase 2b Study

Circulation (New York, N.Y.), 2020-03, Vol.141 (9), p.728-739

2020

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Phytate levels in biological fluids of mammals

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014-06, Vol.960, p.255-257

2014

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Determination of uric acid in urine, saliva and calcium oxalate renal calculi by high-performance liquid chromatography/mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-09, Vol.824 (1), p.175-180

2005

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Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification

Frontiers in pharmacology, 2024-02, Vol.15, p.1325186-1325186

2024

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Effects of Myo-inositol Hexaphosphate (SNF472) on Bone Mineral Density in Patients Receiving Hemodialysis: An Analysis of the Randomized, Placebo-Controlled CaLIPSO Study

Clinical journal of the American Society of Nephrology, 2021-05, Vol.16 (5), p.736-745

2021

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Improvement in wound healing, pain, and quality of life after 12 weeks of SNF472 treatment: a phase 2 open-label study of patients with calciphylaxis

Journal of nephrology, 2019-10, Vol.32 (5), p.811-821

2019

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A phase 1b randomized, placebo‐controlled clinical trial with SNF472 in haemodialysis patients

British journal of clinical pharmacology, 2019-04, Vol.85 (4), p.796-806

2019

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Inositol hexakisphosphate inhibits osteoclastogenesis on RAW 264.7 cells and human primary osteoclasts

PloS one, 2012-08, Vol.7 (8), p.e43187-e43187

2012

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The CALCIPHYX study: a randomized, double-blind, placebo-controlled, Phase 3 clinical trial of SNF472 for the treatment of calciphylaxis

Clinical kidney journal, 2022-01, Vol.15 (1), p.136-144

2022

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A novel assay to measure calcification propensity: from laboratory to humans

Scientific reports, 2020-10, Vol.10 (1), p.17578, Article 17578

2020

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Trial design and baseline characteristics of CaLIPSO: a randomized, double-blind placebo-controlled trial of SNF472 in patients receiving haemodialysis with cardiovascular calcification

Clinical Kidney Journal, 2021-01, Vol.14 (1), p.366-374

2021

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Effects of SNF472, a Novel Inhibitor of Hydroxyapatite Crystallization in Patients Receiving Hemodialysis — Subgroup Analyses of the CALIPSO Trial

Kidney international reports, 2020-12, Vol.5 (12), p.2178-2182

2020

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Mechanistic insights into protonation state as a critical factor in hFPPS enzyme inhibition

Journal of computer-aided molecular design, 2015-07, Vol.29 (7), p.667-680

2015

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Differential Response of MC3T3-E1 and Human Mesenchymal Stem Cells to Inositol Hexakisphosphate

Cellular physiology and biochemistry, 2012-01, Vol.30 (4), p.974-986

2012

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Effect of tetracalcium dimagnesium phytate on bone characteristics in ovariectomized rats

Journal of medicinal food, 2010-12, Vol.13 (6), p.1301-1306

2010

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Mechanism of action of SNF472, a novel calcification inhibitor to treat vascular calcification and calciphylaxis

British journal of pharmacology, 2020-10, Vol.177 (19), p.4400-4415

2020

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Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification

PloS one, 2018-05, Vol.13 (5), p.e0197061-e0197061

2018

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Role of uric acid in different types of calcium oxalate renal calculi

International journal of urology, 2006-03, Vol.13 (3), p.252-256

2006

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Direct Covalent Grafting of Phytate to Titanium Surfaces through Ti–O–P Bonding Shows Bone Stimulating Surface Properties and Decreased Bacterial Adhesion

ACS applied materials & interfaces, 2016-05, Vol.8 (18), p.11326-11335

2016

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Relationship between Urinary Level of Phytate and Valvular Calcification in an Elderly Population: A Cross-Sectional Study

PloS one, 2015-08, Vol.10 (8), p.e0136560-e0136560

2015

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Study of the Absorption of Myo-Inositol Hexakisphosphate (InsP6) through the Skin

Biological and Pharmaceutical Bulletin, 2005, Vol.28(4), pp.764-767

2005

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Hexasodium fytate for the treatment of calciphylaxis: a randomised, double-blind, phase 3, placebo-controlled trial with an open-label extension

EClinicalMedicine, 2024-09, Vol.75, p.102784, Article 102784

2024

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Author Correction: A novel assay to measure calcification propensity: from laboratory to humans

Scientific reports, 2021-02, Vol.11 (1), p.4314-4314, Article 4314

2021

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Plant phosphates, phytate and pathological calcifications in chronic kidney disease

Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2017-01, Vol.37 (1), p.20-28

2017

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SNF472 Improves Limb Blood Perfusion and Walking Ability and Inhibits Progression of Calcification in Femoral Arteries in a Rat Model of Peripheral Artery Disease

Journal of vascular surgery, 2021-09, Vol.74 (3), p.e62-e63

2021

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Slowing Progression of Cardiovascular Calcification With SNF472 in Patients on Hemodialysis: Results of a Randomized Phase 2b Study

Phytate levels in biological fluids of mammals

Determination of uric acid in urine, saliva and calcium oxalate renal calculi by high-performance liquid chromatography/mass spectrometry

Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification

Effects of Myo-inositol Hexaphosphate (SNF472) on Bone Mineral Density in Patients Receiving Hemodialysis: An Analysis of the Randomized, Placebo-Controlled CaLIPSO Study

Improvement in wound healing, pain, and quality of life after 12 weeks of SNF472 treatment: a phase 2 open-label study of patients with calciphylaxis

A phase 1b randomized, placebo‐controlled clinical trial with SNF472 in haemodialysis patients

Inositol hexakisphosphate inhibits osteoclastogenesis on RAW 264.7 cells and human primary osteoclasts

The CALCIPHYX study: a randomized, double-blind, placebo-controlled, Phase 3 clinical trial of SNF472 for the treatment of calciphylaxis

A novel assay to measure calcification propensity: from laboratory to humans

Trial design and baseline characteristics of CaLIPSO: a randomized, double-blind placebo-controlled trial of SNF472 in patients receiving haemodialysis with cardiovascular calcification

Effects of SNF472, a Novel Inhibitor of Hydroxyapatite Crystallization in Patients Receiving Hemodialysis — Subgroup Analyses of the CALIPSO Trial

Mechanistic insights into protonation state as a critical factor in hFPPS enzyme inhibition

Differential Response of MC3T3-E1 and Human Mesenchymal Stem Cells to Inositol Hexakisphosphate

Effect of tetracalcium dimagnesium phytate on bone characteristics in ovariectomized rats

Mechanism of action of SNF472, a novel calcification inhibitor to treat vascular calcification and calciphylaxis

Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification

Role of uric acid in different types of calcium oxalate renal calculi

Direct Covalent Grafting of Phytate to Titanium Surfaces through Ti–O–P Bonding Shows Bone Stimulating Surface Properties and Decreased Bacterial Adhesion

Relationship between Urinary Level of Phytate and Valvular Calcification in an Elderly Population: A Cross-Sectional Study

Study of the Absorption of Myo-Inositol Hexakisphosphate (InsP6) through the Skin

Hexasodium fytate for the treatment of calciphylaxis: a randomised, double-blind, phase 3, placebo-controlled trial with an open-label extension

Author Correction: A novel assay to measure calcification propensity: from laboratory to humans

Plant phosphates, phytate and pathological calcifications in chronic kidney disease

SNF472 Improves Limb Blood Perfusion and Walking Ability and Inhibits Progression of Calcification in Femoral Arteries in a Rat Model of Peripheral Artery Disease

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