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An overview of naturally occurring histone deacetylase inhibitors

Current topics in medicinal chemistry, 2015-01, Vol.14 (24), p.2759-2782

2015

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Crystal Structure of MraY, an Essential Membrane Enzyme for Bacterial Cell Wall Synthesis

Science (American Association for the Advancement of Science), 2013-08, Vol.341 (6149), p.1012-1016

2013

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Chemical logic of MraY inhibition by antibacterial nucleoside natural products

Nature communications, 2019-07, Vol.10 (1), p.2917-12, Article 2917

2019

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Role of natural product diversity in chemical biology

Current opinion in chemical biology, 2011-06, Vol.15 (3), p.350-354

Hong, Jiyong

2011

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REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (46), p.28918-28921

2020

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Enhanced fungal specificity and in vivo therapeutic efficacy of a C-22-modified FK520 analog against C. neoformans

mBio, 2023-10, Vol.14 (5), p.e0181023

2023

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Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor

The Journal of pharmacology and experimental therapeutics, 2010-11, Vol.335 (2), p.351-361

2010

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Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus

mBio, 2022-06, Vol.13 (3), p.e0104922-e0104922

2022

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Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements

Journal of proteome research, 2016-08, Vol.15 (8), p.2688-2696

2016

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A Small Interfering RNA Screen for Modulators of Tumor Cell Motility Identifies MAP4K4 as a Promigratory Kinase

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (10), p.3775-3780

2006

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Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters

eLife, 2014-07, Vol.3, p.e03604

2014

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Biological Evaluation of Subglutinol A As a Novel Immunosuppressive Agent for Inflammation Intervention

ACS medicinal chemistry letters, 2014-05, Vol.5 (5), p.485-490

2014

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Corrigendum: Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

Frontiers in medicine, 2023-05, Vol.10, p.1193745-1193745

2023

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Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

Frontiers in medicine, 2022-12, Vol.9, p.999004

2022

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Largazole pharmacokinetics in rats by LC-MS/MS

Marine drugs, 2014-03, Vol.12 (3), p.1623-1640

2014

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In Vitro and In Vivo Osteogenic Activity of Largazole

ACS medicinal chemistry letters, 2011-03, Vol.2 (3), p.248-251

2011

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Natural product diversity and its role in chemical biology and drug discovery

Current opinion in chemical biology, 2011-04, Vol.15 (3), p.350-354

Hong, Jiyong

2011

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Structural insights into inhibition of lipid I production in bacterial cell wall synthesis

Nature (London), 2016-05, Vol.533 (7604), p.557-560

2016

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A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy

Cell, 2019-06, Vol.178 (1), p.152-159.e11

2019

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Methotrexate recognition by the human reduced folate carrier SLC19A1

Nature (London), 2022-09, Vol.609 (7929), p.1056-1062

2022

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Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy

NAR cancer, 2023-03, Vol.5 (1)

2023

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Length Specificity and Polymerization Mechanism of (1,3)-β‑d‑Glucan Synthase in Fungal Cell Wall Biosynthesis

Biochemistry (Easton), 2020-02, Vol.59 (5), p.682-693

2020

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Methotrexate recognition by the human reduced folate carrier SLC19A1

Biophysical journal, 2023-02, Vol.122 (3), p.398a-399a

2023

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Cryo-EM structure determination of the human reduced folate carrier SLC19A1 in complex with methotrexate

Biophysical journal, 2023-02, Vol.122 (3), p.398a-398a

2023

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Stereoselective Synthesis of Tetrahydrofuran Lignans via BF3·OEt2-Promoted Reductive Deoxygenation/Epimerization of Cyclic Hemiketal: Synthesis of (−)-Odoratisol C, (−)-Futokadsurin A, (−)-Veraguensin, (+)-Fragransin A2, (+)-Galbelgin, and (+)-Talaumidin

Organic letters, 2007-09, Vol.9 (20), p.3965-3968

2007

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An overview of naturally occurring histone deacetylase inhibitors

Crystal Structure of MraY, an Essential Membrane Enzyme for Bacterial Cell Wall Synthesis

Chemical logic of MraY inhibition by antibacterial nucleoside natural products

Role of natural product diversity in chemical biology

REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks

Enhanced fungal specificity and in vivo therapeutic efficacy of a C-22-modified FK520 analog against C. neoformans

Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor

Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus

Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements

A Small Interfering RNA Screen for Modulators of Tumor Cell Motility Identifies MAP4K4 as a Promigratory Kinase

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters

Biological Evaluation of Subglutinol A As a Novel Immunosuppressive Agent for Inflammation Intervention

Corrigendum: Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

Largazole pharmacokinetics in rats by LC-MS/MS

In Vitro and In Vivo Osteogenic Activity of Largazole

Natural product diversity and its role in chemical biology and drug discovery

Structural insights into inhibition of lipid I production in bacterial cell wall synthesis

A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy

Methotrexate recognition by the human reduced folate carrier SLC19A1

Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy

Length Specificity and Polymerization Mechanism of (1,3)-β‑d‑Glucan Synthase in Fungal Cell Wall Biosynthesis

Methotrexate recognition by the human reduced folate carrier SLC19A1

Cryo-EM structure determination of the human reduced folate carrier SLC19A1 in complex with methotrexate

Stereoselective Synthesis of Tetrahydrofuran Lignans via BF3·OEt2-Promoted Reductive Deoxygenation/Epimerization of Cyclic Hemiketal: Synthesis of (−)-Odoratisol C, (−)-Futokadsurin A, (−)-Veraguensin, (+)-Fragransin A2, (+)-Galbelgin, and (+)-Talaumidin

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