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Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Science signaling, 2016-11, Vol.9 (456), p.ra117

2016

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Editorial: Adenylyl cyclase isoforms as potential drug targets

Frontiers in pharmacology, 2022-12, Vol.13, p.1098240-1098240

2022

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Biased Ligands at the Kappa Opioid Receptor: Fine-Tuning Receptor Pharmacology

The Kappa Opioid Receptor, p.115-135

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A Selective Adenylyl Cyclase 1 Inhibitor Relieves Pain Without Causing Tolerance

Frontiers in pharmacology, 2022-07, Vol.13, p.935588

2022

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A “Genome-to-Lead” Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D1-like Dopamine Receptors

PLoS neglected tropical diseases, 2012-01, Vol.6 (1), p.e1478

2012

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Physiological roles of mammalian transmembrane adenylyl cyclase isoforms

Physiological reviews, 2022-04, Vol.102 (2), p.815-857

2022

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Adenylyl cyclase 7 and neuropsychiatric disorders: A new target for depression?

Pharmacological research, 2019-05, Vol.143, p.106-112

2019

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New functional activity of aripiprazole revealed: Robust antagonism of D2 dopamine receptor-stimulated Gβγ signaling

Biochemical pharmacology, 2015-01, Vol.93 (1), p.85-91

2015

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Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties

Science signaling, 2017-02, Vol.10 (467)

2017

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Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways

The Journal of pharmacology and experimental therapeutics, 2015-03, Vol.352 (3), p.480

2015

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Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis

ChemMedChem, 2015-08, Vol.10 (8), p.1351-1364

2015

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Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications

Journal of visualized experiments, 2014-01 (83), p.e51218-e51218

2014

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Discovery of antagonists of tick dopamine receptors via chemical library screening and comparative pharmacological analyses

Insect biochemistry and molecular biology, 2012-11, Vol.42 (11), p.846-853

2012

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Cover Picture: Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis (ChemMedChem 8/2015)

ChemMedChem, 2015-08, Vol.10 (8), p.1277-1277

2015

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Palladium-Catalyzed Regio- and Stereo-Selective γ-Arylation of Tertiary Allylic Amines: Identification of Potent Adenylyl Cyclase Inhibitors

Organic letters, 2015-02, Vol.17 (4), p.892-895

2015

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A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors

PLoS neglected tropical diseases, 2012-01, Vol.6 (1), p.e1478

2012

Volltextzugriff (PDF)

A G Protein‐Biased Ligand of the Kappa Opioid Receptor is Antinociceptive and Antipruritic But Does Not Cause Sedation or Dysphoria

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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ChemInform Abstract: Biased Agonism: An Emerging Paradigm in GPCR Drug Discovery

ChemInform, 2016-02, Vol.47 (9), p.no-no

2016

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Gα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later

European journal of pharmacology, 2015-09, Vol.763 (Pt B), p.223-232

2015

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Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Journal of visualized experiments, 2014-01 (83)

2014

Volltextzugriff (PDF)

A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti [D.sub.1]-like dopamine receptors

PLoS neglected tropical diseases, 2012-01, Vol.6 (1)

2012

Volltextzugriff (PDF)

Adenylyl Cyclases

Reference Module in Life Sciences, 2017

Brust, Tarsis F.

2017

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Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Editorial: Adenylyl cyclase isoforms as potential drug targets

Biased Ligands at the Kappa Opioid Receptor: Fine-Tuning Receptor Pharmacology

A Selective Adenylyl Cyclase 1 Inhibitor Relieves Pain Without Causing Tolerance

A “Genome-to-Lead” Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D1-like Dopamine Receptors

Physiological roles of mammalian transmembrane adenylyl cyclase isoforms

Adenylyl cyclase 7 and neuropsychiatric disorders: A new target for depression?

New functional activity of aripiprazole revealed: Robust antagonism of D2 dopamine receptor-stimulated Gβγ signaling

Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties

Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways

Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis

Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications

Discovery of antagonists of tick dopamine receptors via chemical library screening and comparative pharmacological analyses

Cover Picture: Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis (ChemMedChem 8/2015)

Palladium-Catalyzed Regio- and Stereo-Selective γ-Arylation of Tertiary Allylic Amines: Identification of Potent Adenylyl Cyclase Inhibitors

A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors

A G Protein‐Biased Ligand of the Kappa Opioid Receptor is Antinociceptive and Antipruritic But Does Not Cause Sedation or Dysphoria

ChemInform Abstract: Biased Agonism: An Emerging Paradigm in GPCR Drug Discovery

Gα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti [D.sub.1]-like dopamine receptors

Adenylyl Cyclases

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