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KDM4/JMJD2 Histone Demethylases: Epigenetic Regulators in Cancer Cells

Cancer research (Chicago, Ill.), 2013-05, Vol.73 (10), p.2936-2942

2013

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Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)

Molecular cancer, 2015-07, Vol.14 (1), p.133-133, Article 133

2015

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Epigenetic Resensitization to Platinum in Ovarian Cancer

Cancer research (Chicago, Ill.), 2012-05, Vol.72 (9), p.2197-2205

2012

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Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1

Molecular cancer, 2014-05, Vol.13 (1), p.103-103, Article 103

2014

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Oncogenic features of the JMJD2A histone demethylase in breast cancer

International journal of oncology, 2012-11, Vol.41 (5), p.1701-1706

2012

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DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization

Molecular cancer therapeutics, 2020-07, Vol.19 (7), p.1539-1549

2020

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A case of polycyclic Sweet’s syndrome arising from azacitidine injection sites in myelodysplasia

Annals of hematology, 2020-01, Vol.99 (1), p.201-202

2020

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Docetaxel plus Prednisone or Mitoxantrone plus Prednisone for Advanced Prostate Cancer

The New England journal of medicine, 2004-10, Vol.351 (15), p.1502-1512

2004

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Randomized, Open-Label Phase III Trial of Docetaxel Plus High-Dose Calcitriol Versus Docetaxel Plus Prednisone for Patients With Castration-Resistant Prostate Cancer

Journal of clinical oncology, 2011-06, Vol.29 (16), p.2191-2198

2011

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Targeting doublecortin-like kinase 1 reveals a novel strategy to circumvent chemoresistance and metastasis in ovarian cancer

Cancer letters, 2023-12, Vol.578, p.216437, Article 216437

2023

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FGF1 supports glycolytic metabolism through the estrogen receptor in endocrine-resistant and obesity-associated breast cancer

Breast cancer research : BCR, 2023-08, Vol.25 (1), p.99-99, Article 99

2023

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Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer

International journal of cancer, 2018-09, Vol.143 (5), p.1162-1175

2018

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Pembrolizumab in men with heavily treated metastatic castrate‐resistant prostate cancer

Cancer medicine (Malden, MA), 2019-08, Vol.8 (10), p.4644-4655

2019

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Stimulation of β-catenin and colon cancer cell growth by the KDM4B histone demethylase

International journal of oncology, 2014-04, Vol.44 (4), p.1341-1348

2014

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DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

Oncotarget, 2015-02, Vol.6 (4), p.2193-2205

2015

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Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy

Urologic oncology, 2012-09, Vol.30 (5), p.607-613

2012

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The role of sex in the innate and adaptive immune environment of metastatic colorectal cancer

British journal of cancer, 2020-08, Vol.123 (4), p.624-632

2020

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Multinational, Double-Blind, Phase III Study of Prednisone and Either Satraplatin or Placebo in Patients With Castrate-Refractory Prostate Cancer Progressing After Prior Chemotherapy: The SPARC Trial

Journal of clinical oncology, 2009-11, Vol.27 (32), p.5431-5438

2009

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Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide

Clinical cancer research, 2021-07, Vol.27 (14), p.4077-4088

2021

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Combination of Radiation Therapy and Short-Term Androgen Blockade With Abiraterone Acetate Plus Prednisone for Men With High- and Intermediate-Risk Localized Prostate Cancer

International journal of radiation oncology, biology, physics, 2021-04, Vol.109 (5), p.1271-1278

2021

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Updated 5-year results for short course abiraterone acetate and LHRH agonist for unfavorable intermediate and favorable high-risk prostate cancer

Prostate cancer and prostatic diseases, 2024-02

2024

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Phase I Study of Seviteronel, a Selective CYP17 Lyase and Androgen Receptor Inhibitor, in Men with Castration-Resistant Prostate Cancer

Clinical cancer research, 2018-11, Vol.24 (21), p.5225-5232

2018

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Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14), p.4090-4099

2016

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Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data

The lancet oncology, 2007-11, Vol.8 (11), p.994-1000

2007

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KDM4/JMJD2 Histone Demethylases: Epigenetic Regulators in Cancer Cells

Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study

Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)

Epigenetic Resensitization to Platinum in Ovarian Cancer

Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1

Oncogenic features of the JMJD2A histone demethylase in breast cancer

DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization

A case of polycyclic Sweet’s syndrome arising from azacitidine injection sites in myelodysplasia

Docetaxel plus Prednisone or Mitoxantrone plus Prednisone for Advanced Prostate Cancer

Randomized, Open-Label Phase III Trial of Docetaxel Plus High-Dose Calcitriol Versus Docetaxel Plus Prednisone for Patients With Castration-Resistant Prostate Cancer

Targeting doublecortin-like kinase 1 reveals a novel strategy to circumvent chemoresistance and metastasis in ovarian cancer

FGF1 supports glycolytic metabolism through the estrogen receptor in endocrine-resistant and obesity-associated breast cancer

Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer

Pembrolizumab in men with heavily treated metastatic castrate‐resistant prostate cancer

Stimulation of β-catenin and colon cancer cell growth by the KDM4B histone demethylase

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy

The role of sex in the innate and adaptive immune environment of metastatic colorectal cancer

Multinational, Double-Blind, Phase III Study of Prednisone and Either Satraplatin or Placebo in Patients With Castrate-Refractory Prostate Cancer Progressing After Prior Chemotherapy: The SPARC Trial

Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide

Combination of Radiation Therapy and Short-Term Androgen Blockade With Abiraterone Acetate Plus Prednisone for Men With High- and Intermediate-Risk Localized Prostate Cancer

Updated 5-year results for short course abiraterone acetate and LHRH agonist for unfavorable intermediate and favorable high-risk prostate cancer

Phase I Study of Seviteronel, a Selective CYP17 Lyase and Androgen Receptor Inhibitor, in Men with Castration-Resistant Prostate Cancer

Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase

Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data

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