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Challenges of antibacterial discovery revisited

Annals of the New York Academy of Sciences, 2010-12, Vol.1213 (1), p.5-19

2010

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Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics

Antimicrobial agents and chemotherapy, 2017-09, Vol.61 (9)

2017

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Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

Frontiers in immunology, 2021-07, Vol.12, p.705360-705360

2021

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Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections

Antimicrobial agents and chemotherapy, 2015-01, Vol.59 (1), p.289-298

2015

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A rapid microtiter plate assay for measuring the effect of compounds on Staphylococcus aureus membrane potential

Journal of microbiological methods, 2010-11, Vol.83 (2), p.254-256

2010

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In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains

Antimicrobial agents and chemotherapy, 2016-02, Vol.60 (2), p.729-734

2016

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In vitro antimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria

Journal of antimicrobial chemotherapy, 2016-03, Vol.71 (3), p.670-677

2016

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Efficacy of Human Exposures of Gepotidacin (GSK2140944) against Escherichia coli in a Rat Pyelonephritis Model

Antimicrobial agents and chemotherapy, 2019-07, Vol.63 (7)

2019

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Reducing Antibacterial Development Risk for GSK1322322 by Exploring Potential Human Dose Regimens in Nonclinical Efficacy Studies Using Immunocompetent Rats

Antimicrobial agents and chemotherapy, 2017-11, Vol.61 (11)

2017

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Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in Rodent Models of Infection

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.180-189

2016

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1560. Pharmacokinetics–Pharmacodynamics (PK-PD) of Gepotidacin (GEP) Against Escherichia coli in Murine Pyelonephritis and Thigh Infection Models

Open forum infectious diseases, 2019-10, Vol.6 (Supplement_2), p.S569-S569

2019

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A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Journal of visualized experiments, 2017-01 (119)

2017

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A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Journal of visualized experiments, 2017-01 (119)

2017

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248S-649266, a Novel Siderophore Cephalosporin: Efficacy against Klebsiella pneumoniae producing NDM-1 or KPC in rat lung infection model with recreated humanized exposure profile of 2 gram dose with 1 hour and 3 hours infusion

Open forum infectious diseases, 2014-12, Vol.1 (suppl_1), p.S106-S107

2014

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In vitro activity of gemifloxacin against a broad range of recent clinical isolates from the USA

Journal of antimicrobial chemotherapy, 2000-04, Vol.45 (suppl-3), p.13-13

2000

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In vitro antibacterial activity of gemifloxacin and comparator compounds against common respiratory pathogens

Journal of antimicrobial chemotherapy, 2000-04, Vol.45 (suppl-3), p.23-23

2000

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Information from your family doctor: Questions and answers about TB

American family physician, 2000-05, Vol.61 (9), p.2681

2000

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Identification and management of tuberculosis

American family physician, 2000-05, Vol.61 (9), p.2667-2678

2000

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Low- versus high-pressure irrigation techniques in Staphylococcus aureus-inoculated wounds

The American journal of emergency medicine, 1999-03, Vol.17 (2), p.121-124

1999

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Structure and antimicrobial activity of new bile acid-based gemini surfactants

Perkin 2 : an international journal of physical organic chemistry, 2002-06 (7), p.1302-1306

2002

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A survey of β-lactamase-producing Haemophilus influenzae an evaluation of 5750 isolates

Diagnostic microbiology and infectious disease, 1995-04, Vol.21 (4), p.223-225

1995

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Pharmacological properties of dynorphin A -(2 -17) and structurally related novel peptides

Rittenhouse, Stephen F

2001

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Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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The evolution of antimicrobial susceptibility testing methods

Advances in experimental medicine and biology, 1994, Vol.349, p.3

1994

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Conformational Perturbation of the Envelope Glycoprotein gp120 of Human Immunodeficiency Virus Type 1 by Soluble CD4 and the Lectin Succinyl Con A

Virology (New York, N.Y.), 1993-06, Vol.194 (2), p.833-837

1993

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Challenges of antibacterial discovery revisited

Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics

Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections

A rapid microtiter plate assay for measuring the effect of compounds on Staphylococcus aureus membrane potential

In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains

In vitro antimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria

Efficacy of Human Exposures of Gepotidacin (GSK2140944) against Escherichia coli in a Rat Pyelonephritis Model

Reducing Antibacterial Development Risk for GSK1322322 by Exploring Potential Human Dose Regimens in Nonclinical Efficacy Studies Using Immunocompetent Rats

Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in Rodent Models of Infection

1560. Pharmacokinetics–Pharmacodynamics (PK-PD) of Gepotidacin (GEP) Against Escherichia coli in Murine Pyelonephritis and Thigh Infection Models

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

248S-649266, a Novel Siderophore Cephalosporin: Efficacy against Klebsiella pneumoniae producing NDM-1 or KPC in rat lung infection model with recreated humanized exposure profile of 2 gram dose with 1 hour and 3 hours infusion

In vitro activity of gemifloxacin against a broad range of recent clinical isolates from the USA

In vitro antibacterial activity of gemifloxacin and comparator compounds against common respiratory pathogens

Information from your family doctor: Questions and answers about TB

Identification and management of tuberculosis

Low- versus high-pressure irrigation techniques in Staphylococcus aureus-inoculated wounds

Structure and antimicrobial activity of new bile acid-based gemini surfactants

A survey of β-lactamase-producing Haemophilus influenzae an evaluation of 5750 isolates

Pharmacological properties of dynorphin A -(2 -17) and structurally related novel peptides

Nanomolar Inhibitors of Staphylococcus a ureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

The evolution of antimicrobial susceptibility testing methods

Conformational Perturbation of the Envelope Glycoprotein gp120 of Human Immunodeficiency Virus Type 1 by Soluble CD4 and the Lectin Succinyl Con A

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