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A New Chiral Rh(II) Catalyst for Enantioselective [2 + 1]-Cycloaddition. Mechanistic Implications and Applications

Journal of the American Chemical Society, 2004-07, Vol.126 (29), p.8916-8918

2004

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Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists

ACS medicinal chemistry letters, 2013-04, Vol.4 (4), p.419-422

2013

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Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

Journal of organic chemistry, 2000-12, Vol.65 (24), p.8379-8380

2000

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Formal Synthesis of (±)-Guanacastepene A

Journal of organic chemistry, 2003-02, Vol.68 (3), p.1030-1042

2003

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Synthesis of (−)-Dysiherbaine

Organic letters, 2000-03, Vol.2 (5), p.635-638

2000

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Synthesis of the Hydroazulene Ring System of Guanacastepene

Organic letters, 2001-02, Vol.3 (4), p.569-572

2001

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Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures1

Journal of the American Chemical Society, 2001-10, Vol.123 (43), p.10475-10488

2001

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PHARMACOLOGICAL CHARACTERIZATION OF A PURINERGIC RECEPTOR (P2X7) ANTAGONIST IN‐VITRO AND IN‐VIVO

The FASEB journal, 2010-04, Vol.24 (S1), p.lb460-lb460

2010

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Discovery and synthesis of 6,7,8,9-tetrahydro-5 H-pyrimido-[4,5- d]azepines as novel TRPV1 antagonists

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (23), p.7137-7141

2010

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Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X 7 Antagonists

ACS medicinal chemistry letters, 2013-04, Vol.4 (4), p.419-422

2013

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1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5 H-pyrimido[4,5- d]azepines as TRPV1 antagonists with improved properties

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (23), p.7142-7146

2010

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In‐vitro and in‐vivo pharmacology of a novel TRPV1 receptor antagonist: JNJ38748021

The FASEB journal, 2008-03, Vol.22 (S1)

2008

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2‐Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists

Vanilloid Receptor TRPV1 in Drug Discovery, 2010, p.311-324

2010

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Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures 1

Journal of the American Chemical Society, 2001-10, Vol.123 (43), p.10475-10488

2001

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ChemInform Abstract: Synthesis of the Hydroazulene Ring System of Guanacastepene

ChemInform, 2001-06, Vol.32 (25), p.no-no

2001

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ChemInform Abstract: Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

ChemInform, 2001-04, Vol.32 (16), p.no-no

2001

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ChemInform Abstract: Synthesis of (-)-Dysiherbaine

ChemInform, 2000-06, Vol.31 (25), p.no-no

2000

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Formal Synthesis of (.+-.)-Guanacastepene A

ChemInform, 2003-06, Vol.34 (23), p.no-no

2003

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A New Chiral Rh(II) Catalyst for Enantioselective [2 + 1]-Cycloaddition. Mechanistic Implications and Applications

ChemInform, 2004-11, Vol.35 (44), p.no-no

2004

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Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

Immunity (Cambridge, Mass.), 2012-08, Vol.37 (2), p.339-350

2012

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Abstract 15612: EDG-7500, a Novel Cardiac Sarcomere Regulator That Preserves Intrinsic Myosin-Motor Function, Improves Cardiac Function and Reserve in a Minipig Model of Hypertrophic Cardiomyopathy

Circulation (New York, N.Y.), 2023-11, Vol.148 (Suppl_1)

2023

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Abstract 15822: Cardiac Effects of EDG-7500, a Novel Cardiac Sarcomere Regulator: In vitro and in vivo Evidence for Slowing Isovolumic Contraction and Improved Ventricular Compliance

Circulation (New York, N.Y.), 2023-11, Vol.148 (Suppl_1)

2023

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Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing

JAMA dermatology (Chicago, Ill.), 2023-05, Vol.159 (5), p.545

2023

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Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB

PLoS pathogens, 2020-06, Vol.16 (6), p.e1008567-e1008567

2020

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EDG-002, A NOVEL TARGETED SARCOMERE REGULATOR PRESERVES INTRINSIC MYOSIN-MOTOR FUNCTION, BLUNTS HYPERCONTRACTILITY AND ELIMINATES LVOT OBSTRUCTION IN CATS WITH HYPERTROPHIC CARDIOMYOPATHY: IN VITRO AND IN VIVO EVIDENCE

Journal of the American College of Cardiology, 2023-03, Vol.81 (8), p.349-349

2023

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A New Chiral Rh(II) Catalyst for Enantioselective [2 + 1]-Cycloaddition. Mechanistic Implications and Applications

Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists

Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

Formal Synthesis of (±)-Guanacastepene A

Synthesis of (−)-Dysiherbaine

Synthesis of the Hydroazulene Ring System of Guanacastepene

Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures1

PHARMACOLOGICAL CHARACTERIZATION OF A PURINERGIC RECEPTOR (P2X7) ANTAGONIST IN‐VITRO AND IN‐VIVO

Discovery and synthesis of 6,7,8,9-tetrahydro-5 H-pyrimido-[4,5- d]azepines as novel TRPV1 antagonists

Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X 7 Antagonists

1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5 H-pyrimido[4,5- d]azepines as TRPV1 antagonists with improved properties

In‐vitro and in‐vivo pharmacology of a novel TRPV1 receptor antagonist: JNJ38748021

2‐Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists

Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures 1

ChemInform Abstract: Synthesis of the Hydroazulene Ring System of Guanacastepene

ChemInform Abstract: Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

ChemInform Abstract: Synthesis of (-)-Dysiherbaine

Formal Synthesis of (.+-.)-Guanacastepene A

A New Chiral Rh(II) Catalyst for Enantioselective [2 + 1]-Cycloaddition. Mechanistic Implications and Applications

Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

Abstract 15612: EDG-7500, a Novel Cardiac Sarcomere Regulator That Preserves Intrinsic Myosin-Motor Function, Improves Cardiac Function and Reserve in a Minipig Model of Hypertrophic Cardiomyopathy

Abstract 15822: Cardiac Effects of EDG-7500, a Novel Cardiac Sarcomere Regulator: In vitro and in vivo Evidence for Slowing Isovolumic Contraction and Improved Ventricular Compliance

Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing

Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB

EDG-002, A NOVEL TARGETED SARCOMERE REGULATOR PRESERVES INTRINSIC MYOSIN-MOTOR FUNCTION, BLUNTS HYPERCONTRACTILITY AND ELIMINATES LVOT OBSTRUCTION IN CATS WITH HYPERTROPHIC CARDIOMYOPATHY: IN VITRO AND IN VIVO EVIDENCE

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