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Molecular Mechanisms of the Cardiotoxicity of the Proteasomal-Targeted Drugs Bortezomib and Carfilzomib

Cardiovascular toxicology, 2017-07, Vol.17 (3), p.237-250

2017

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Evaluation of Nitrobenzyl Derivatives of Camptothecin as Anti-Cancer Agents and Potential Hypoxia Targeting Prodrugs

Molecules (Basel, Switzerland), 2018-08, Vol.23 (8), p.2041

2018

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Progress curve analysis of the kinetics of slow-binding anticancer drug inhibitors of the 20S proteasome

Archives of biochemistry and biophysics, 2018-02, Vol.639, p.52-58

Hasinoff, Brian B.

2018

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Disulfiram is a slow-binding partial noncompetitive inhibitor of 20S proteasome activity

Archives of biochemistry and biophysics, 2017-11, Vol.633, p.23-28

2017

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Mechanisms of Myocyte Cytotoxicity Induced by the Multikinase Inhibitor Sorafenib

Cardiovascular toxicology, 2010-03, Vol.10 (1), p.1-8

2010

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Mechanisms of the Cardiac Myocyte-Damaging Effects of Dasatinib

Cardiovascular toxicology, 2020-08, Vol.20 (4), p.380-389

2020

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The Role of Topoisomerase IIβ in the Mechanisms of Action of the Doxorubicin Cardioprotective Agent Dexrazoxane

Cardiovascular toxicology, 2020-06, Vol.20 (3), p.312-320

2020

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The cytotoxicity of the anticancer drug elesclomol is due to oxidative stress indirectly mediated through its complex with Cu(II)

Journal of inorganic biochemistry, 2014-08, Vol.137, p.22-30

2014

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Myocyte-Damaging Effects and Binding Kinetics of Boronic Acid and Epoxyketone Proteasomal-Targeted Drugs

Cardiovascular toxicology, 2018-12, Vol.18 (6), p.557-568

2018

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The Myocyte-Damaging Effects of the BCR-ABL1-Targeted Tyrosine Kinase Inhibitors Increase with Potency and Decrease with Specificity

Cardiovascular toxicology, 2017-07, Vol.17 (3), p.297-306

2017

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Molecular mechanisms of the biological activity of the anticancer drug elesclomol and its complexes with Cu(II), Ni(II) and Pt(II)

Journal of inorganic biochemistry, 2013-09, Vol.126, p.1-6

2013

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Abstract 3060: Molecular mechanisms of the cardiotoxicity of the proteasomal-targeted anticancer drugs bortezomib and carfilzomib

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3060-3060

2016

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Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F

Free radical biology & medicine, 2007-10, Vol.43 (8), p.1132-1144

2007

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Total Synthesis of Isoprekinamycin: Structural Evidence for Enhanced Diazonium Ion Character and Growth Inhibitory Activity toward Cancer Cells

Organic letters, 2007-07, Vol.9 (15), p.2915-2918

2007

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Dexrazoxane use in the prevention of anthracycline extravasation injury

Future oncology (London, England), 2006-02, Vol.2 (1), p.15-20

Hasinoff, Brian B

2006

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Expression of a stress‐induced hemoglobin affects NO levels produced by alfalfa root cultures under hypoxic stress

The Plant journal : for cell and molecular biology, 2003-09, Vol.35 (6), p.763-770

2003

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Class-1 hemoglobins, nitrate and NO levels in anoxic maize cell-suspension cultures

Planta, 2004-05, Vol.219 (1), p.66-72

2004

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Dexrazoxane: how it works in cardiac and tumor cells. Is it a prodrug or is it a drug?

Cardiovascular toxicology, 2007-06, Vol.7 (2), p.140-144

2007

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The oral iron chelator ICL670A (deferasirox) does not protect myocytes against doxorubicin

Free radical biology & medicine, 2003-12, Vol.35 (11), p.1469-1479

2003

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The intracellular iron sensor calcein is catalytically oxidatively degraded by iron(II) in a hydrogen peroxide-dependent reaction

Journal of inorganic biochemistry, 2003-06, Vol.95 (2), p.157-164

Hasinoff, Brian B.

2003

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The iron chelator Dp44mT does not protect myocytes against doxorubicin

Journal of inorganic biochemistry, 2009-07, Vol.103 (7), p.1093-1101

2009

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Dexrazoxane (ICRF-187) protects cardiac myocytes against doxorubicin by preventing damage to mitochondria

Cardiovascular toxicology, 2003, Vol.3 (2), p.89-100

2003

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Cell lysis with dimethyl sulphoxide produces stable homogeneous solutions in the dichlorofluorescein oxidative stress assay

Free radical research, 2008-05, Vol.42 (5), p.435-441

2008

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The Dual-Targeted HER1/HER2 Tyrosine Kinase Inhibitor Lapatinib Strongly Potentiates the Cardiac Myocyte-Damaging Effects of Doxorubicin

Cardiovascular toxicology, 2013-03, Vol.13 (1), p.33-47

2013

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Abstract 1878: Molecular mechanisms of the cardiotoxicity of the proteasomal-targeted anticancer drugs bortezomib, carfilzomib, ixazomib, oprozomib, and delanzomib

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1878-1878

Hasinoff, Brian B.

2018

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Molecular Mechanisms of the Cardiotoxicity of the Proteasomal-Targeted Drugs Bortezomib and Carfilzomib

Evaluation of Nitrobenzyl Derivatives of Camptothecin as Anti-Cancer Agents and Potential Hypoxia Targeting Prodrugs

Progress curve analysis of the kinetics of slow-binding anticancer drug inhibitors of the 20S proteasome

Disulfiram is a slow-binding partial noncompetitive inhibitor of 20S proteasome activity

Mechanisms of Myocyte Cytotoxicity Induced by the Multikinase Inhibitor Sorafenib

Mechanisms of the Cardiac Myocyte-Damaging Effects of Dasatinib

The Role of Topoisomerase IIβ in the Mechanisms of Action of the Doxorubicin Cardioprotective Agent Dexrazoxane

The cytotoxicity of the anticancer drug elesclomol is due to oxidative stress indirectly mediated through its complex with Cu(II)

Myocyte-Damaging Effects and Binding Kinetics of Boronic Acid and Epoxyketone Proteasomal-Targeted Drugs

The Myocyte-Damaging Effects of the BCR-ABL1-Targeted Tyrosine Kinase Inhibitors Increase with Potency and Decrease with Specificity

Molecular mechanisms of the biological activity of the anticancer drug elesclomol and its complexes with Cu(II), Ni(II) and Pt(II)

Abstract 3060: Molecular mechanisms of the cardiotoxicity of the proteasomal-targeted anticancer drugs bortezomib and carfilzomib

Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F

Total Synthesis of Isoprekinamycin: Structural Evidence for Enhanced Diazonium Ion Character and Growth Inhibitory Activity toward Cancer Cells

Dexrazoxane use in the prevention of anthracycline extravasation injury

Expression of a stress‐induced hemoglobin affects NO levels produced by alfalfa root cultures under hypoxic stress

Class-1 hemoglobins, nitrate and NO levels in anoxic maize cell-suspension cultures

Dexrazoxane: how it works in cardiac and tumor cells. Is it a prodrug or is it a drug?

The oral iron chelator ICL670A (deferasirox) does not protect myocytes against doxorubicin

The intracellular iron sensor calcein is catalytically oxidatively degraded by iron(II) in a hydrogen peroxide-dependent reaction

The iron chelator Dp44mT does not protect myocytes against doxorubicin

Dexrazoxane (ICRF-187) protects cardiac myocytes against doxorubicin by preventing damage to mitochondria

Cell lysis with dimethyl sulphoxide produces stable homogeneous solutions in the dichlorofluorescein oxidative stress assay

The Dual-Targeted HER1/HER2 Tyrosine Kinase Inhibitor Lapatinib Strongly Potentiates the Cardiac Myocyte-Damaging Effects of Doxorubicin

Abstract 1878: Molecular mechanisms of the cardiotoxicity of the proteasomal-targeted anticancer drugs bortezomib, carfilzomib, ixazomib, oprozomib, and delanzomib

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