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Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase a-dependent mechanism

Glia, 2001-03, Vol.33 (4), p.324-333

2001

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Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4636-4642

2004

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Antiviral Activity of Nucleoside Analogues against SARS-coronavirus (SARS-CoV)

Antiviral chemistry & chemotherapy, 2006-10, Vol.17 (5), p.285-289

2006

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Anticancer activity of β-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration

Cancer research (Chicago, Ill.), 1995-07, Vol.55 (14), p.3008-3011

1995

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PAMAM Dendrimers and Branched Polyethyleneglycol (Nanoparticles) Prodrugs of (-)-β-D-(2R, 4R)-dioxolane-thymine (DOT) and Their Anti-HIV Activity

Antiviral chemistry & chemotherapy, 2006-12, Vol.17 (6), p.321-329

2006

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Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents

Biochemical pharmacology, 2007-05, Vol.73 (10), p.1558-1572

2007

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Interaction of 2′-deoxyguanosine Triphosphate Analogue Inhibitors of HIV Reverse Transcriptase with Human Mitochondrial DNA Polymerase γ

Antiviral chemistry & chemotherapy, 2007-02, Vol.18 (1), p.25-33

2007

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Structure−Activity Relationships of l-Dioxolane Uracil Nucleosides as Anti-Epstein Barr Virus Agents

Journal of medicinal chemistry, 1999-06, Vol.42 (12), p.2212-2217

1999

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Probing the Mechanistic Consequences of 5-Fluorine Substitution on Cytidine Nucleotide Analogue Incorporation by HIV-1 Reverse Transcriptase

Antiviral Chemistry and Chemotherapy, 2003-06, Vol.14 (3), p.115-125

2003

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Molecular Mechanism of DAPD/DXG against Zidovudine- and Lamivudine- Drug Resistant Mutants: A Molecular Modelling Approach

Antiviral chemistry & chemotherapy, 2002-04, Vol.13 (2), p.115-128

2002

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Mechanism of Antiviral Activities of 3′-Substituted L-Nucleosides against 3Tc-Resistant HBV Polymerase: A Molecular Modelling Approach

Antiviral chemistry & chemotherapy, 2003-12, Vol.14 (6), p.309-319

2003

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Pharmacokinetics of (-)-β-D-dioxolane guanine and prodrug (-)-β-D-2,6-diaminopurine dioxolane in rats and monkeys

AIDS research and human retroviruses, 1999-12, Vol.15 (18), p.1625-1630

1999

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Pharmacokinetic Evaluation of 3′-Azido-2′, 3′-Dideoxyuridine-5′-O-Valinate-Hydrochloride as a Prodrug of the Anti-HIV Nucleoside 3′-Azido-2′, 3′-Dideoxyuridine

Antiviral chemistry & chemotherapy, 2003-10, Vol.14 (5), p.263-270

2003

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Comparison of cytotoxicity of the (−)- and (+)- enantiomer of 2′,3′- dideoxy-3′-thiacytidine in normal human bone marrow progenitor cells

Biochemical pharmacology, 1992-11, Vol.44 (10), p.1921-1925

1992

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Antiestrogenic piperidinediones designed prospectively using computer graphics and energy calculations of DNA-ligand complexes

The Journal of steroid biochemistry and molecular biology, 1994-04, Vol.48 (5), p.495-505

1994

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Pharmacology and pharmacokinetics of the antiviral agent β-D2',3'-dideoxy-3'-oxa-5-fluorocytidine in cells and rhesus monkeys

Antimicrobial agents and chemotherapy, 2005, Vol.49 (7), p.2589-2597

2005

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Asymmetric synthesis and anti-HIV activity of L-carbocyclic 2′,3′-didehydro-2′,3′-dideoxyadenosine

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (13), p.1585-1588

1998

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Correlation between Preferred Sugar Ring Conformation and Activity of Nucleoside Analogues against Human Immunodeficiency Virus

Proceedings of the National Academy of Sciences - PNAS, 1989-06, Vol.86 (11), p.3929-3933

1989

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Determination of 3′-azido-2′,3′-dideoxyuridine in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography

Journal of chromatography. B, Biomedical sciences and applications, 2001-05, Vol.755 (1), p.165-172

2001

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Characterization of hepatitis B virus inhibition by novel 2'-fluoro-2',3'-unsaturated beta-D- and L-nucleo sides

Antiviral chemistry & chemotherapy, 2005, Vol.16 (3), p.183-192

2005

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Synthesis of β-enantiomers of N4-hydroxy-3'-deoxypyrimidine nucleosides and their evaluation against bovine viral diarrhoea virus and hepatitis C virus in cell culture

Antiviral chemistry & chemotherapy, 2004, Vol.15 (1), p.43-55

2004

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Advances in antiviral agents for hepatitis B virus

Antiviral chemistry & chemotherapy, 2001, Vol.12, p.93-117

2001

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19F NMR Study of the Uptake of 2′-Fluoro-5-methyl-β- l-arabinofuranosyluracil in Erythrocytes : Evidence of Transport by Facilitated and Nonfacilitated Pathways

Biochemical pharmacology, 1998-05, Vol.55 (10), p.1611-1619

1998

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Design of novel antiestrogens

Journal of steroid biochemistry and molecular biology, 1994-06, Vol.49 (4), p.269-280

1994

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In Vitro and in Vivo Evaluation of 6-Azido-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosylpurine and N6-Methyl-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosyladenine as Prodrugs of the Anti-HIV Nucleosides 2‘-F-ara-ddA and 2‘-F-ara-ddI

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4676-4681

1996

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Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase a-dependent mechanism

Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

Antiviral Activity of Nucleoside Analogues against SARS-coronavirus (SARS-CoV)

Anticancer activity of β-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration

PAMAM Dendrimers and Branched Polyethyleneglycol (Nanoparticles) Prodrugs of (-)-β-D-(2R, 4R)-dioxolane-thymine (DOT) and Their Anti-HIV Activity

Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents

Interaction of 2′-deoxyguanosine Triphosphate Analogue Inhibitors of HIV Reverse Transcriptase with Human Mitochondrial DNA Polymerase γ

Structure−Activity Relationships of l-Dioxolane Uracil Nucleosides as Anti-Epstein Barr Virus Agents

Probing the Mechanistic Consequences of 5-Fluorine Substitution on Cytidine Nucleotide Analogue Incorporation by HIV-1 Reverse Transcriptase

Molecular Mechanism of DAPD/DXG against Zidovudine- and Lamivudine- Drug Resistant Mutants: A Molecular Modelling Approach

Mechanism of Antiviral Activities of 3′-Substituted L-Nucleosides against 3Tc-Resistant HBV Polymerase: A Molecular Modelling Approach

Pharmacokinetics of (-)-β-D-dioxolane guanine and prodrug (-)-β-D-2,6-diaminopurine dioxolane in rats and monkeys

Pharmacokinetic Evaluation of 3′-Azido-2′, 3′-Dideoxyuridine-5′-O-Valinate-Hydrochloride as a Prodrug of the Anti-HIV Nucleoside 3′-Azido-2′, 3′-Dideoxyuridine

Comparison of cytotoxicity of the (−)- and (+)- enantiomer of 2′,3′- dideoxy-3′-thiacytidine in normal human bone marrow progenitor cells

Antiestrogenic piperidinediones designed prospectively using computer graphics and energy calculations of DNA-ligand complexes

Pharmacology and pharmacokinetics of the antiviral agent β-D2',3'-dideoxy-3'-oxa-5-fluorocytidine in cells and rhesus monkeys

Asymmetric synthesis and anti-HIV activity of L-carbocyclic 2′,3′-didehydro-2′,3′-dideoxyadenosine

Correlation between Preferred Sugar Ring Conformation and Activity of Nucleoside Analogues against Human Immunodeficiency Virus

Determination of 3′-azido-2′,3′-dideoxyuridine in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography

Characterization of hepatitis B virus inhibition by novel 2'-fluoro-2',3'-unsaturated beta-D- and L-nucleo sides

Synthesis of β-enantiomers of N4-hydroxy-3'-deoxypyrimidine nucleosides and their evaluation against bovine viral diarrhoea virus and hepatitis C virus in cell culture

Advances in antiviral agents for hepatitis B virus

19F NMR Study of the Uptake of 2′-Fluoro-5-methyl-β- l-arabinofuranosyluracil in Erythrocytes : Evidence of Transport by Facilitated and Nonfacilitated Pathways

Design of novel antiestrogens

In Vitro and in Vivo Evaluation of 6-Azido-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosylpurine and N6-Methyl-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosyladenine as Prodrugs of the Anti-HIV Nucleosides 2‘-F-ara-ddA and 2‘-F-ara-ddI

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