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Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

PloS one, 2013-08, Vol.8 (8), p.e71196

2013

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Blockade of Tetrahydrobiopterin Synthesis Protects Neurons after Transient Forebrain Ischemia in Rat: A Novel Role for the Cofactor

The Journal of neuroscience, 1999-02, Vol.19 (3), p.878-889

1999

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Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase a-dependent mechanism

Glia, 2001-03, Vol.33 (4), p.324-333

2001

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Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4636-4642

2004

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L-nucleosides: antiviral activity and molecular mechanism

Current topics in medicinal chemistry, 2002-10, Vol.2 (10), p.1065-1086

2002

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Antiviral Activity of Nucleoside Analogues against SARS-coronavirus (SARS-CoV)

Antiviral chemistry & chemotherapy, 2006-10, Vol.17 (5), p.285-289

2006

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Determination of acyclovir in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002-06, Vol.772 (2), p.327-334

2002

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Anticancer activity of β-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration

Cancer research (Chicago, Ill.), 1995-07, Vol.55 (14), p.3008-3011

1995

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PAMAM Dendrimers and Branched Polyethyleneglycol (Nanoparticles) Prodrugs of (-)-β-D-(2R, 4R)-dioxolane-thymine (DOT) and Their Anti-HIV Activity

Antiviral chemistry & chemotherapy, 2006-12, Vol.17 (6), p.321-329

2006

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Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents

Biochemical pharmacology, 2007-05, Vol.73 (10), p.1558-1572

2007

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Simultaneous determination of 3′-azido-2′,3′-dideoxyuridine and novel prodrugs in rat plasma by liquid chromatography

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-10, Vol.795 (2), p.371-376

2003

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Pharmacokinetics of (-)-β-D-dioxolane guanine and prodrug (-)-β-D-2,6-diaminopurine dioxolane in rats and monkeys

AIDS research and human retroviruses, 1999-12, Vol.15 (18), p.1625-1630

1999

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Pharmacokinetic Evaluation of 3′-Azido-2′, 3′-Dideoxyuridine-5′-O-Valinate-Hydrochloride as a Prodrug of the Anti-HIV Nucleoside 3′-Azido-2′, 3′-Dideoxyuridine

Antiviral chemistry & chemotherapy, 2003-10, Vol.14 (5), p.263-270

2003

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Nucleosides. CXXXV. : Synthesis of Some 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purines and Their Biological Activities

Chemical and Pharmaceutical Bulletin, 1989/02/25, Vol.37(2), pp.336-339

1989

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Asymmetric synthesis and anti-HIV activity of L-carbocyclic 2′,3′-didehydro-2′,3′-dideoxyadenosine

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (13), p.1585-1588

1998

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Determination of 3′-azido-2′,3′-dideoxyuridine in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography

Journal of chromatography. B, Biomedical sciences and applications, 2001-05, Vol.755 (1), p.165-172

2001

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SYNTHESIS OF CARBOCYCLIC OROTIDINE ANALOGS AS POTENTIAL OROTIDINE DECARBOXYLASE INHIBITORS

Nucleosides, nucleotides & nucleic acids, 2001-12, Vol.20 (12), p.1915-1925

2001

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Synthesis of 2,3-dideoxy-2,2-difluoro- l- glycero-pentofuranosyl nucleosides

Carbohydrate research, 1998, Vol.306 (1), p.69-80

1998

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Metabolism and effects of 5-(beta-D-ribofuranosyl)isocytosine in P815 cells

Cancer research (Chicago, Ill.), 1979-03, Vol.39 (3), p.720-728

1979

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Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides

Nucleosides, nucleotides & nucleic acids, 2005, Vol.24 (5-7), p.875

2005

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Synthesis of β-enantiomers of N4-hydroxy-3'-deoxypyrimidine nucleosides and their evaluation against bovine viral diarrhoea virus and hepatitis C virus in cell culture

Antiviral chemistry & chemotherapy, 2004, Vol.15 (1), p.43-55

2004

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Design of novel antiestrogens

Journal of steroid biochemistry and molecular biology, 1994-06, Vol.49 (4), p.269-280

1994

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In Vitro and in Vivo Evaluation of 6-Azido-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosylpurine and N6-Methyl-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosyladenine as Prodrugs of the Anti-HIV Nucleosides 2‘-F-ara-ddA and 2‘-F-ara-ddI

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4676-4681

1996

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Comparative pharmacokinetics and interspecies scaling of 3'-azido-3'-deoxythymidine (AZT) in several mammalian species

Journal of pharmacobio-dynamics, 1990, Vol.13 (3), p.206-211

1990

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Inhibition of estrogen stimulated mitogenesis by 3-phenylacetylamino-2,6-piperidinedione and its Para-hydroxy analog

The Journal of steroid biochemistry and molecular biology, 1993-10, Vol.46 (4), p.451-462

1993

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Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

Blockade of Tetrahydrobiopterin Synthesis Protects Neurons after Transient Forebrain Ischemia in Rat: A Novel Role for the Cofactor

Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase a-dependent mechanism

Metabolism of the Anti-Hepatitis C Virus Nucleoside β-d-N4-Hydroxycytidine in Different Liver Cells

L-nucleosides: antiviral activity and molecular mechanism

Antiviral Activity of Nucleoside Analogues against SARS-coronavirus (SARS-CoV)

Determination of acyclovir in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography

Anticancer activity of β-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration

PAMAM Dendrimers and Branched Polyethyleneglycol (Nanoparticles) Prodrugs of (-)-β-D-(2R, 4R)-dioxolane-thymine (DOT) and Their Anti-HIV Activity

Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents

Simultaneous determination of 3′-azido-2′,3′-dideoxyuridine and novel prodrugs in rat plasma by liquid chromatography

Pharmacokinetics of (-)-β-D-dioxolane guanine and prodrug (-)-β-D-2,6-diaminopurine dioxolane in rats and monkeys

Pharmacokinetic Evaluation of 3′-Azido-2′, 3′-Dideoxyuridine-5′-O-Valinate-Hydrochloride as a Prodrug of the Anti-HIV Nucleoside 3′-Azido-2′, 3′-Dideoxyuridine

Nucleosides. CXXXV. : Synthesis of Some 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purines and Their Biological Activities

Asymmetric synthesis and anti-HIV activity of L-carbocyclic 2′,3′-didehydro-2′,3′-dideoxyadenosine

Determination of 3′-azido-2′,3′-dideoxyuridine in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography

SYNTHESIS OF CARBOCYCLIC OROTIDINE ANALOGS AS POTENTIAL OROTIDINE DECARBOXYLASE INHIBITORS

Synthesis of 2,3-dideoxy-2,2-difluoro- l- glycero-pentofuranosyl nucleosides

Metabolism and effects of 5-(beta-D-ribofuranosyl)isocytosine in P815 cells

Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides

Synthesis of β-enantiomers of N4-hydroxy-3'-deoxypyrimidine nucleosides and their evaluation against bovine viral diarrhoea virus and hepatitis C virus in cell culture

Design of novel antiestrogens

In Vitro and in Vivo Evaluation of 6-Azido-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosylpurine and N6-Methyl-2‘,3‘-dideoxy-2‘-fluoro-β-d-arabinofuranosyladenine as Prodrugs of the Anti-HIV Nucleosides 2‘-F-ara-ddA and 2‘-F-ara-ddI

Comparative pharmacokinetics and interspecies scaling of 3'-azido-3'-deoxythymidine (AZT) in several mammalian species

Inhibition of estrogen stimulated mitogenesis by 3-phenylacetylamino-2,6-piperidinedione and its Para-hydroxy analog

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