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Virtual screening and in vitro experiments highlight cannabidiol as a drug‐like phosphodiesterase 9 inhibitor

The European journal of neuroscience, 2023-06, Vol.57 (12), p.1954-1965

2023

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Cannabidiol preferentially binds TRPV2: a novel mechanism of action

Neural regeneration research, 2022-12, Vol.17 (12), p.2693-2694

2022

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Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model

Neurobiology of disease, 2022-11, Vol.174, p.105895-105895, Article 105895

2022

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The Neuroprotective Effects of mGlu1 Receptor Antagonists Are Mediated by an Enhancement of GABAergic Synaptic Transmission via a Presynaptic CB1 Receptor Mechanism

Cells (Basel, Switzerland), 2022-09, Vol.11 (19), p.3015

2022

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Experimental Models for Testing the Efficacy of Pharmacological Treatments for Neonatal Hypoxic-Ischemic Encephalopathy

Biomedicines, 2022-04, Vol.10 (5), p.937

2022

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Neuronal and Astrocytic Morphological Alterations Driven by Prolonged Exposure with Δ9-Tetrahydrocannabinol but Not Cannabidiol

Toxics (Basel), 2022-01, Vol.10 (2), p.48

2022

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Neuroprotective Effects of Cannabidiol but Not Δ9-Tetrahydrocannabinol in Rat Hippocampal Slices Exposed to Oxygen-Glucose Deprivation: Studies with Cannabis Extracts and Selected Cannabinoids

International journal of molecular sciences, 2021-09, Vol.22 (18), p.9773

2021

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Ethanol neurotoxicity is mediated by changes in expression, surface localization and functional properties of glutamate AMPA receptors

Journal of neurochemistry, 2021-06, Vol.157 (6), p.2106-2118

2021

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Changes in physical activity levels, eating habits and psychological well-being during the Italian COVID-19 pandemic lockdown: Impact of socio-demographic factors on the Florentine academic population

PloS one, 2021-05, Vol.16 (5), p.e0252395-e0252395

2021

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Co-expression of the SARS-CoV-2 entry receptors ACE2 and TMPRSS2 in healthy human conjunctiva

Experimental eye research, 2021-04, Vol.205, p.108527-108527, Article 108527

2021

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A new ophthalmic formulation containing antiseptics and dexpanthenol: In vitro antimicrobial activity and effects on corneal and conjunctival epithelial cells

Experimental eye research, 2020-12, Vol.201, p.108269, Article 108269

2020

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Tolerance Induced by (S)-3,5-Dihydroxyphenylglycine Postconditioning is Mediated by the PI3K/Akt/GSK3β Signalling Pathway in an In Vitro Model of Cerebral Ischemia

Neuroscience, 2020-05, Vol.433, p.221-229

2020

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Reconsolidation of sucrose instrumental memory in rats: The role of retrieval context

Brain research, 2019-07, Vol.1714, p.193-201

2019

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Chitosan coated human serum albumin nanoparticles: A promising strategy for nose-to-brain drug delivery

International journal of biological macromolecules, 2019-05, Vol.129, p.267-280

2019

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Glutamate Receptor-Mediated Neurotoxicity in a Model of Ethanol Dependence and Withdrawal in Rat Organotypic Hippocampal Slice Cultures

Frontiers in neuroscience, 2019-01, Vol.12, p.1053-1053

2019

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Using organotypic hippocampal slice cultures to gain insight into mechanisms responsible for the neuroprotective effects of meloxicam: a role for gamma aminobutyric and endoplasmic reticulum stress

Neural regeneration research, 2019-01, Vol.14 (1), p.65-66

2019

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The metaplastic effects of NMDA receptors blockade on reactivation of instrumental memories in rats

Neurobiology of learning and memory, 2018-10, Vol.154, p.87-96

2018

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Neuroprotective effects of topiramate and memantine in combination with hypothermia in hypoxic-ischemic brain injury in vitro and in vivo

Neuroscience letters, 2018-03, Vol.668, p.103-107

2018

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Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation

Colloids and surfaces, B, Biointerfaces, 2018-01, Vol.161, p.302-313

2018

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The gliadin peptide 31-43 exacerbates kainate neurotoxicity in epilepsy models

Scientific reports, 2017-11, Vol.7 (1), p.15146-10, Article 15146

2017

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Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-01, Vol.71 (1), p.50-60

2016

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Glutamate and Stroke: From NMDA to mGlu Receptors and Beyond

Rational Basis for Clinical Translation in Stroke Therapy, 2015, p.350-363

2015

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Azithromycin: assessment of intrinsic cytotoxic effects on corneal epithelial cell cultures

Clinical ophthalmology (Auckland, N.Z.), 2013-01, Vol.7 (default), p.965-971

2013

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In vitro comparison of the cytotoxic effects of clinically available ophthalmic solutions of fluoroquinolones on human keratocytes

Canadian journal of ophthalmology, 2011-12, Vol.46 (6), p.513-520

2011

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Topiramate concentrations in neonates treated with prolonged whole body hypothermia for hypoxic ischemic encephalopathy

Epilepsia (Copenhagen), 2009-11, Vol.50 (11), p.2355-2361

2009

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Virtual screening and in vitro experiments highlight cannabidiol as a drug‐like phosphodiesterase 9 inhibitor

Cannabidiol preferentially binds TRPV2: a novel mechanism of action

Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model

The Neuroprotective Effects of mGlu1 Receptor Antagonists Are Mediated by an Enhancement of GABAergic Synaptic Transmission via a Presynaptic CB1 Receptor Mechanism

Experimental Models for Testing the Efficacy of Pharmacological Treatments for Neonatal Hypoxic-Ischemic Encephalopathy

Neuronal and Astrocytic Morphological Alterations Driven by Prolonged Exposure with Δ9-Tetrahydrocannabinol but Not Cannabidiol

Neuroprotective Effects of Cannabidiol but Not Δ9-Tetrahydrocannabinol in Rat Hippocampal Slices Exposed to Oxygen-Glucose Deprivation: Studies with Cannabis Extracts and Selected Cannabinoids

Ethanol neurotoxicity is mediated by changes in expression, surface localization and functional properties of glutamate AMPA receptors

Changes in physical activity levels, eating habits and psychological well-being during the Italian COVID-19 pandemic lockdown: Impact of socio-demographic factors on the Florentine academic population

Co-expression of the SARS-CoV-2 entry receptors ACE2 and TMPRSS2 in healthy human conjunctiva

A new ophthalmic formulation containing antiseptics and dexpanthenol: In vitro antimicrobial activity and effects on corneal and conjunctival epithelial cells

Tolerance Induced by (S)-3,5-Dihydroxyphenylglycine Postconditioning is Mediated by the PI3K/Akt/GSK3β Signalling Pathway in an In Vitro Model of Cerebral Ischemia

Reconsolidation of sucrose instrumental memory in rats: The role of retrieval context

Chitosan coated human serum albumin nanoparticles: A promising strategy for nose-to-brain drug delivery

Glutamate Receptor-Mediated Neurotoxicity in a Model of Ethanol Dependence and Withdrawal in Rat Organotypic Hippocampal Slice Cultures

Using organotypic hippocampal slice cultures to gain insight into mechanisms responsible for the neuroprotective effects of meloxicam: a role for gamma aminobutyric and endoplasmic reticulum stress

The metaplastic effects of NMDA receptors blockade on reactivation of instrumental memories in rats

Neuroprotective effects of topiramate and memantine in combination with hypothermia in hypoxic-ischemic brain injury in vitro and in vivo

Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation

The gliadin peptide 31-43 exacerbates kainate neurotoxicity in epilepsy models

Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models

Glutamate and Stroke: From NMDA to mGlu Receptors and Beyond

Azithromycin: assessment of intrinsic cytotoxic effects on corneal epithelial cell cultures

In vitro comparison of the cytotoxic effects of clinically available ophthalmic solutions of fluoroquinolones on human keratocytes

Topiramate concentrations in neonates treated with prolonged whole body hypothermia for hypoxic ischemic encephalopathy

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