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A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Cell metabolism, 2016-03, Vol.23 (3), p.427-440

2016

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Stochastic gene expression out-of-steady-state in the cyanobacterial circadian clock

Nature, 2007-12, Vol.450 (7173), p.1249-1252

2007

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Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome

Drug metabolism and disposition, 2017-05, Vol.45 (5), p.501-511

2017

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Probing Polymerization Forces by Using Actin-Propelled Lipid Vesicles

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (8), p.4521-4526

2003

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Assessing the Feasibility of Neutralizing Osteopontin with Various Therapeutic Antibody Modalities

Scientific reports, 2018-05, Vol.8 (1), p.7781-7, Article 7781

2018

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A Mechanistic Site-Of-Action Model: A Tool for Informing Right Target, Right Compound, And Right Dose for Therapeutic Antagonistic Antibody Programs

Frontiers in bioinformatics, 2021-09, Vol.1, p.731340-731340

2021

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Social context of shell acquisition in Coenobita clypeatus hermit crabs

Behavioral ecology, 2010-05, Vol.21 (3), p.639-646

2010

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Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents

Journal of medicinal chemistry, 2018-07, Vol.61 (13), p.5704-5718

2018

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Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis

Angewandte Chemie International Edition, 2017-12, Vol.56 (51), p.16218-16222

International ed. in English, 2017

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Physiologically relevant binding affinity quantification of monoclonal antibody PF‐00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation

British journal of pharmacology, 2017-01, Vol.174 (1), p.70-81

2017

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Analysis of Mechanistic Pathway Models in Drug Discovery: p38 Pathway

Biotechnology progress, 2008-01, Vol.24 (1), p.96-109

2008

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Two additive mechanisms impair the differentiation of 'substrate-selective' p38 inhibitors from classical p38 inhibitors in vitro

BMC systems biology, 2010-03, Vol.4 (1), p.23-23, Article 23

2010

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Pendent polyimides using mellitic acid dianhydride. III. The effect of pendent group functionality on polymer properties

Journal of applied polymer science, 2009-07, Vol.113 (2), p.1198-1206

2009

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Abstract 3056: Growth differentiation factor 15 (GDF-15) inhibition attenuates platinum-based chemotherapy-induced emesis, anorexia and weight loss and increases survival

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3056-3056

2020

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Pharmacokinetics and Integrated PK/PD Modeling of a Novel Long Acting FGF21 Clinical Candidate PF-05231023 in Diet-Induced Obese and Leptin-Deficient Obese Mice

PloS one, 2015-03, Vol.10 (3)

2015

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Modeling Efficacy and Safety of Engineered Biologics

Drug Efficacy, Safety, and Biologics Discovery, 2008, p.301-326

2008

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Analysis of Mechanistic Pathway Models in Drug Discovery : p38 Pathway : Integration of biological design principles from molecules to cells

Biotechnology progress, 2008, Vol.24 (1), p.96-109

2008

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Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools

1. Aufl., 2009

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Genetic noise in the cyanobacterial circadian oscillator

Chabot, Jeffrey R

2005

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Insights on Immune Function in Free-Ranging Green Sea Turtles ( Chelonia mydas ) with and without Fibropapillomatosis

Animals (Basel), 2021-03, Vol.11 (3), p.861

2021

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A Sea Turtle Population Assessment for Florida's Big Bend, Northeastern Gulf of Mexico

Gulf and Caribbean research, 2021, Vol.32 (1), p.19-33

2021

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Manipulation of Distinct NFκB Proteins Alters Interleukin-1β-induced Human Rheumatoid Synovial Fibroblast Prostaglandin E2 Formation

The Journal of biological chemistry, 1996-12, Vol.271 (49), p.31496-31501

1996

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Manipulation of Distinct NFÎºB Proteins Alters Interleukin-1Î²-induced Human Rheumatoid Synovial Fibroblast Prostaglandin E2 Formation

The Journal of biological chemistry, 1996-12, Vol.271 (49), p.31496

1996

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A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Stochastic gene expression out-of-steady-state in the cyanobacterial circadian clock

Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome

Probing Polymerization Forces by Using Actin-Propelled Lipid Vesicles

Assessing the Feasibility of Neutralizing Osteopontin with Various Therapeutic Antibody Modalities

A Mechanistic Site-Of-Action Model: A Tool for Informing Right Target, Right Compound, And Right Dose for Therapeutic Antagonistic Antibody Programs

Social context of shell acquisition in Coenobita clypeatus hermit crabs

Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents

Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis

Physiologically relevant binding affinity quantification of monoclonal antibody PF‐00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation

Analysis of Mechanistic Pathway Models in Drug Discovery: p38 Pathway

Two additive mechanisms impair the differentiation of 'substrate-selective' p38 inhibitors from classical p38 inhibitors in vitro

Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis

Pendent polyimides using mellitic acid dianhydride. III. The effect of pendent group functionality on polymer properties

Abstract 3056: Growth differentiation factor 15 (GDF-15) inhibition attenuates platinum-based chemotherapy-induced emesis, anorexia and weight loss and increases survival

Pharmacokinetics and Integrated PK/PD Modeling of a Novel Long Acting FGF21 Clinical Candidate PF-05231023 in Diet-Induced Obese and Leptin-Deficient Obese Mice

Modeling Efficacy and Safety of Engineered Biologics

Analysis of Mechanistic Pathway Models in Drug Discovery : p38 Pathway : Integration of biological design principles from molecules to cells

Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools

Genetic noise in the cyanobacterial circadian oscillator

Insights on Immune Function in Free-Ranging Green Sea Turtles ( Chelonia mydas ) with and without Fibropapillomatosis

A Sea Turtle Population Assessment for Florida's Big Bend, Northeastern Gulf of Mexico

Manipulation of Distinct NFκB Proteins Alters Interleukin-1β-induced Human Rheumatoid Synovial Fibroblast Prostaglandin E2 Formation

Manipulation of Distinct NFÎºB Proteins Alters Interleukin-1Î²-induced Human Rheumatoid Synovial Fibroblast Prostaglandin E2 Formation

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