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Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals

Advanced drug delivery reviews, 2020-01, Vol.154-155, p.163-175

2020

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Liposomal Delivery Systems: Design Optimization and Current Applications

Biological and Pharmaceutical Bulletin, 2017/01/01, Vol.40(1), pp.1-10

2017

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Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

International journal of pharmaceutics, 2008-04, Vol.354 (1), p.56-62

2008

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The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage

Journal of controlled release, 2013-11, Vol.172 (1), p.38-47

2013

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Neutralization of Acidic Tumor Microenvironment (TME) with Daily Oral Dosing of Sodium Potassium Citrate (K/Na Citrate) Increases Therapeutic Effect of Anti-cancer Agent in Pancreatic Cancer Xenograft Mice Model

Biological and Pharmaceutical Bulletin, 2021/02/01, Vol.44(2), pp.266-270

2021

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Anti-PEG IgM Is a Major Contributor to the Accelerated Blood Clearance of Polyethylene Glycol-Conjugated Protein

Molecular pharmaceutics, 2015-07, Vol.12 (7), p.2429-2435

2015

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Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products

Journal of controlled release, 2022-11, Vol.351, p.215-230

2022

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PEGylated liposomes: immunological responses

Science and technology of advanced materials, 2019-12, Vol.20 (1), p.710-724

2019

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A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research

Biological and Pharmaceutical Bulletin, 2018/05/01, Vol.41(5), pp.733-742

2018

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PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: Faster PEG shedding attenuates anti-PEG IgM production

International journal of pharmaceutics, 2020-10, Vol.588, p.119792, Article 119792

2020

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Importance of Process Parameters Influencing the Mean Diameters of siRNA-Containing Lipid Nanoparticles (LNPs) on the in Vitro Activity of Prepared LNPs

Biological and Pharmaceutical Bulletin, 2022/04/01, Vol.45(4), pp.497-507

2022

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Aseptic meningitis after vaccination of the BNT162b2 mRNA COVID-19 vaccine

Neurological sciences, 2021-11, Vol.42 (11), p.4433-4435

2021

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Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes

Journal of controlled release, 2007-06, Vol.119 (2), p.236-244

2007

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Increasing Tumor Extracellular pH by an Oral Alkalinizing Agent Improves Antitumor Responses of Anti-PD-1 Antibody: Implication of Relationships between Serum Bicarbonate Concentrations, Urinary pH, and Therapeutic Outcomes

Biological and Pharmaceutical Bulletin, 2021/06/01, Vol.44(6), pp.844-852

2021

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Anti-polyethyleneglycol Antibody Response to PEGylated Substances

Biological and Pharmaceutical Bulletin, 2013/06/01, Vol.36(6), pp.889-891

2013

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Potential Efficacy of Proteasome Inhibitor, Delanzomib, for the Treatment of Renal Fibrosis

Biological and Pharmaceutical Bulletin, 2023/02/01, Vol.46(2), pp.279-285

2023

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Intravenous Administration of Polyethylene Glycol-Coated (PEGylated) Proteins and PEGylated Adenovirus Elicits an Anti-PEG Immunoglobulin M Response

Biological and Pharmaceutical Bulletin, 2012/08/01, Vol.35(8), pp.1336-1342

2012

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Development of a Nanocarrier-Based Splenic B Cell-Targeting System for Loading Antigens in Vitro

Biological and Pharmaceutical Bulletin, 2022/07/01, Vol.45(7), pp.926-933

2022

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Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation

Biological and Pharmaceutical Bulletin, 2022/01/01, Vol.45(1), pp.129-135

2022

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A Maleimide-Terminally Modified PEGylated Liposome Induced the Accelerated Blood Clearance Independent of the Production of Anti-PEG IgM Antibodies

Biological and Pharmaceutical Bulletin, 2022/10/01, Vol.45(10), pp.1518-1524

2022

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Foreword

Chemical & pharmaceutical bulletin, 2022-01, Vol.70 (5), p.309

2022

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Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice

Journal of controlled release, 2021-06, Vol.334, p.327-334

2021

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Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration

International journal of pharmaceutics, 2013-11, Vol.456 (1), p.235-242

2013

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The New Delivery Strategy of Albumin Carrier Utilizing the Interaction with Albumin Receptors

Chemical and Pharmaceutical Bulletin, 2022/05/01, Vol.70(5), pp.330-333

2022

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Complement activation induced by PEG enhances humoral immune responses against antigens encapsulated in PEG-modified liposomes

Journal of controlled release, 2021-01, Vol.329, p.1046-1053

2021

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Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals

Liposomal Delivery Systems: Design Optimization and Current Applications

Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage

Neutralization of Acidic Tumor Microenvironment (TME) with Daily Oral Dosing of Sodium Potassium Citrate (K/Na Citrate) Increases Therapeutic Effect of Anti-cancer Agent in Pancreatic Cancer Xenograft Mice Model

Anti-PEG IgM Is a Major Contributor to the Accelerated Blood Clearance of Polyethylene Glycol-Conjugated Protein

Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products

PEGylated liposomes: immunological responses

A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research

PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: Faster PEG shedding attenuates anti-PEG IgM production

Importance of Process Parameters Influencing the Mean Diameters of siRNA-Containing Lipid Nanoparticles (LNPs) on the in Vitro Activity of Prepared LNPs

Aseptic meningitis after vaccination of the BNT162b2 mRNA COVID-19 vaccine

Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes

Increasing Tumor Extracellular pH by an Oral Alkalinizing Agent Improves Antitumor Responses of Anti-PD-1 Antibody: Implication of Relationships between Serum Bicarbonate Concentrations, Urinary pH, and Therapeutic Outcomes

Anti-polyethyleneglycol Antibody Response to PEGylated Substances

Potential Efficacy of Proteasome Inhibitor, Delanzomib, for the Treatment of Renal Fibrosis

Intravenous Administration of Polyethylene Glycol-Coated (PEGylated) Proteins and PEGylated Adenovirus Elicits an Anti-PEG Immunoglobulin M Response

Development of a Nanocarrier-Based Splenic B Cell-Targeting System for Loading Antigens in Vitro

Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation

A Maleimide-Terminally Modified PEGylated Liposome Induced the Accelerated Blood Clearance Independent of the Production of Anti-PEG IgM Antibodies

Foreword

Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice

Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration

The New Delivery Strategy of Albumin Carrier Utilizing the Interaction with Albumin Receptors

Complement activation induced by PEG enhances humoral immune responses against antigens encapsulated in PEG-modified liposomes

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