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Comprehensive characterization of Epimedium-Rhizoma drynariae herb pair in rat plasma, urine, and feces metabolic profiles by UHPLC-Q-Orbitrap HRMS combined with diagnostic extraction strategy and multicomponent pharmacokinetic study by UHPLC-MS/MS

Analytical and bioanalytical chemistry, 2024-06, Vol.416 (14), p.3415-3432

2024

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Genotoxicity assessments of N-nitrosoethylisopropylamine (NEIPA) and N-nitrosodiisopropylamine (NDIPA) in the C57BL/6J mouse

Mutation research. Genetic toxicology and environmental mutagenesis, 2024-05, Vol.896, p.503763, Article 503763

2024

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The Atypical Antipsychotic Lurasidone Affects Brain but Not Liver Cytochrome P450 2D (CYP2D) Activity. A Comparison with Other Novel Neuroleptics and Significance for Drug Treatment of Schizophrenia

Cells (Basel, Switzerland), 2022-11, Vol.11 (21), p.3513

2022

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Streptozotocin-induced Diabetes Represses Hepatic CYP2R1 Expression but Induces Vitamin D 25-Hydroxylation in Male Mice

Endocrinology (Philadelphia), 2022-07, Vol.163 (7), p.1

2022

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Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling

eLife, 2022-02, Vol.11

2022

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Sex-Dependent Environmental Health Risk Analysis of Flupyradifurone

Environmental science & technology, 2022-02, Vol.56 (3), p.1841-1853

2022

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Serum Vitamin D: Correlates of Baseline Concentration and Response to Supplementation in VITAL-DKD

The journal of clinical endocrinology and metabolism, 2022-02, Vol.107 (2), p.525-537

2022

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Toxicokinetics, in vivo metabolic profiling, and in vitro metabolism of gelsenicine in rats

Archives of toxicology, 2022-02, Vol.96 (2), p.525-533

2022

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Development and Validation of a Novel HPLC Method to Analyse Metabolic Reaction Products Catalysed by the CYP3A2 Isoform: In Vitro Inhibition of CYP3A2 Enzyme Activity by Aspirin (Drugs Often Used Together in COVID-19 Treatment)

Molecules (Basel, Switzerland), 2022-01, Vol.27 (3), p.927

2022

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Identification and Validation of PLOD2 as an Adverse Prognostic Biomarker for Oral Squamous Cell Carcinoma

Biomolecules (Basel, Switzerland), 2021-12, Vol.11 (12), p.1842

2021

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Systematic characterization of the absorbed components of Ligustri Lucidi Fructus and their metabolic pathways in rat plasma by ultra‐high‐performance liquid chromatography‐Q‐Exactive Orbitrap tandem mass spectrometry combined with network pharmacology

Journal of separation science, 2021-12, Vol.44 (24), p.4343-4367

2021

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Application of liquid chromatography coupled to data-independent acquisition mass spectrometry for the metabolic profiling of N-ethyl heptedrone

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-11, Vol.1185, p.122989-122989, Article 122989

2021

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Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells

Journal of cellular biochemistry, 2021-11, Vol.122 (11), p.1737-1748

2021

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P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis

Oncogene, 2021-10, Vol.40 (41), p.6049-6056

2021

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Characterization of metabolic fate of phellodendrine and its potential pharmacological mechanism against diabetes mellitus by ultra‐high‐performance liquid chromatography‐coupled time‐of‐flight mass spectrometry and network pharmacology

Rapid communications in mass spectrometry, 2021-09, Vol.35 (18), p.e9157-n/a

2021

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New insights into vitamin D regulation: is there a role for alkaline phosphatase?

Journal of endocrinological investigation, 2021-09, Vol.44 (9), p.1891-1896

2021

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The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced status epilepticus

Brain research, 2021-08, Vol.1764, p.147468-147468, Article 147468

2021

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Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A41G allele function

Clinical and translational science, 2021-07, Vol.14 (4), p.1292-1302

2021

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Steroidogenic cytochrome P450 17A1 structure and function

Molecular and cellular endocrinology, 2021-05, Vol.528, p.111261-111261, Article 111261

2021

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2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis

Cancer research (Chicago, Ill.), 2021-01, Vol.81 (2), p.289-302

2021

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Serum lipoprotein–derived fatty acids regulate hypoxia-inducible factor

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.18284-18300

2020

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Accelerated whole-body protein catabolism in subjects with type 2 Diabetes Mellitus and albuminuria

PloS one, 2020-12, Vol.15 (12), p.e0243638-e0243638

2020

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The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation

The Journal of biological chemistry, 2020-12, Vol.295 (50), p.17158-17168

2020

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12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020-12, Vol.1865 (12), p.158811-158811, Article 158811

2020

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Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons

The Journal of neuroscience, 2020-11, Vol.40 (47), p.9012-9027

2020

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Comprehensive characterization of Epimedium-Rhizoma drynariae herb pair in rat plasma, urine, and feces metabolic profiles by UHPLC-Q-Orbitrap HRMS combined with diagnostic extraction strategy and multicomponent pharmacokinetic study by UHPLC-MS/MS

Genotoxicity assessments of N-nitrosoethylisopropylamine (NEIPA) and N-nitrosodiisopropylamine (NDIPA) in the C57BL/6J mouse

The Atypical Antipsychotic Lurasidone Affects Brain but Not Liver Cytochrome P450 2D (CYP2D) Activity. A Comparison with Other Novel Neuroleptics and Significance for Drug Treatment of Schizophrenia

Streptozotocin-induced Diabetes Represses Hepatic CYP2R1 Expression but Induces Vitamin D 25-Hydroxylation in Male Mice

Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling

Sex-Dependent Environmental Health Risk Analysis of Flupyradifurone

Serum Vitamin D: Correlates of Baseline Concentration and Response to Supplementation in VITAL-DKD

Toxicokinetics, in vivo metabolic profiling, and in vitro metabolism of gelsenicine in rats

Development and Validation of a Novel HPLC Method to Analyse Metabolic Reaction Products Catalysed by the CYP3A2 Isoform: In Vitro Inhibition of CYP3A2 Enzyme Activity by Aspirin (Drugs Often Used Together in COVID-19 Treatment)

Identification and Validation of PLOD2 as an Adverse Prognostic Biomarker for Oral Squamous Cell Carcinoma

Systematic characterization of the absorbed components of Ligustri Lucidi Fructus and their metabolic pathways in rat plasma by ultra‐high‐performance liquid chromatography‐Q‐Exactive Orbitrap tandem mass spectrometry combined with network pharmacology

Application of liquid chromatography coupled to data-independent acquisition mass spectrometry for the metabolic profiling of N-ethyl heptedrone

Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells

P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis

Characterization of metabolic fate of phellodendrine and its potential pharmacological mechanism against diabetes mellitus by ultra‐high‐performance liquid chromatography‐coupled time‐of‐flight mass spectrometry and network pharmacology

New insights into vitamin D regulation: is there a role for alkaline phosphatase?

The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced status epilepticus

Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A41G allele function

Steroidogenic cytochrome P450 17A1 structure and function

2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis

Serum lipoprotein–derived fatty acids regulate hypoxia-inducible factor

Accelerated whole-body protein catabolism in subjects with type 2 Diabetes Mellitus and albuminuria

The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation

12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats

Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons

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