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Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

Oncotarget, 2016-05, Vol.7 (20), p.28976-28988

2016

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Reactive Oxygen Species Generation and Mitochondrial Dysfunction in the Apoptotic Response to Bortezomib, a Novel Proteasome Inhibitor, in Human H460 Non-small Cell Lung Cancer Cells

The Journal of biological chemistry, 2003-09, Vol.278 (36), p.33714-33723

2003

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Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis

Blood, 2004-11, Vol.104 (9), p.2746-2751

2004

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Phase II clinical trial data with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) in non-small-cell lung cancer

Clinical lung cancer, 2004-12, Vol.6 Suppl 1, p.S20-S23

Perez-Soler, Roman

2004

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Mechanisms of Proteasome Inhibitor PS-341-induced G2-M-Phase Arrest and Apoptosis in Human Non-Small Cell Lung Cancer Cell Lines

Clinical cancer research, 2003-03, Vol.9 (3), p.1145-1154

2003

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Arsenic Trioxide Produces Polymerization of Microtubules and Mitotic Arrest before Apoptosis in Human Tumor Cell Lines

Molecular pharmacology, 2002-09, Vol.62 (3), p.529-538

2002

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Phosphorylation of Bcl-2 Is a Marker of M Phase Events and Not a Determinant of Apoptosis

The Journal of biological chemistry, 1998-07, Vol.273 (30), p.18984-18991

1998

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Treatment of Non–Small-Cell Lung Cancer with Erlotinib or Gefitinib

The New England journal of medicine, 2011-03, Vol.364 (10), p.947-955

2011

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Erlotinib Induces Mitochondrial-Mediated Apoptosis in Human H3255 Non-Small-Cell Lung Cancer Cells with Epidermal Growth Factor ReceptorL858R Mutation through Mitochondrial Oxidative Phosphorylation-Dependent Activation of BAX and BAK

Molecular pharmacology, 2008-09, Vol.74 (3), p.793-806

2008

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Investigators Look Past Standard Immunotherapy for Additional Lung Cancer Solutions: "That's the beauty of science. Anything can be intellectual."

Oncology (Williston Park, N.Y.), 2021-09, Vol.35 (9), p.526

Perez-Soler, Roman

2021

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Targeting Angiogenesis in Squamous Non-Small Cell Lung Cancer

Drugs (New York, N.Y.), 2014-03, Vol.74 (4), p.403-413

2014

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Structure-Based Design of a New Bisintercalating Anthracycline Antibiotic

Journal of medicinal chemistry, 1997-01, Vol.40 (3), p.261-266

1997

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Intercalation of erlotinib and pemetrexed in the treatment of non-small cell lung cancer

Current drug targets, 2010-01, Vol.11 (1), p.85-94

2010

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Erlotinib, an Effective Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Induces p27KIP1 Up-Regulation and Nuclear Translocation in Association with Cell Growth Inhibition and G1/S Phase Arrest in Human Non-Small-Cell Lung Cancer Cell Lines

Molecular pharmacology, 2007-08, Vol.72 (2), p.248-258

2007

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Nanoparticle albumin bound-paclitaxel for treatment of advanced non-small cell lung cancer: an evaluation of the clinical evidence

Expert opinion on pharmacotherapy, 2019-01, Vol.20 (1), p.95-102

2019

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Role of Erlotinib in the Treatment of Non-Small Cell Lung Cancer: Clinical Outcomes in Wild-Type Epidermal Growth Factor Receptor Patients

Drugs (New York, N.Y.), 2012-06, Vol.72 (Suppl 1), p.11-19

2012

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Indirect measurements of differential gene expression with cDNA microarrays

BioTechniques, 2004-02, Vol.36 (2), p.310-314

2004

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Abstract 4748: RICTOR signaling modulates the activity of EGFR tyrosine kinase inhibitors (TKI) in EGFR -mutated non-small cell lung cancer (NSCLC)

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4748-4748

2019

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Abstract 2740: MET exon 14 skipping mutation promotes metastasis via activation of the PI3K/Akt-Rac1 pathway in non-small cell lung cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2740-2740

2019

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Abstract 4907: A novel functional analysis of MET exon 14 skipping mutation in regulation of tumor cell invasion and metastasis

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.4907-4907

2020

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Abstract 589: DNA demethylating agent and histone deacetylation inhibitor synergistically induce paired box 5 gene expression in non-small cell lung cancer cell lines

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.589-589

2014

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Targeting the PI3K/AKT/mTOR pathway: potential for lung cancer treatment

Lung cancer management, 2014-02, Vol.3 (1), p.67-75

2014

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Abstract 1017: RICTOR/mTOR signaling regulates novel immune checkpoints in non-small cell lung cancer (NSCLC)

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1017-1017

2020

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RICTOR amplification as a novel therapeutic target for lung cancer brain metastases

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.3597-3597

2020

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Abstract 1217: Blockade of Aurora kinase A synergizes with platinum and radiation in non-small cell lung cancer cells

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1217-1217

2017

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Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

Reactive Oxygen Species Generation and Mitochondrial Dysfunction in the Apoptotic Response to Bortezomib, a Novel Proteasome Inhibitor, in Human H460 Non-small Cell Lung Cancer Cells

Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis

Phase II clinical trial data with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) in non-small-cell lung cancer

Mechanisms of Proteasome Inhibitor PS-341-induced G2-M-Phase Arrest and Apoptosis in Human Non-Small Cell Lung Cancer Cell Lines

Arsenic Trioxide Produces Polymerization of Microtubules and Mitotic Arrest before Apoptosis in Human Tumor Cell Lines

Phosphorylation of Bcl-2 Is a Marker of M Phase Events and Not a Determinant of Apoptosis

Treatment of Non–Small-Cell Lung Cancer with Erlotinib or Gefitinib

Erlotinib Induces Mitochondrial-Mediated Apoptosis in Human H3255 Non-Small-Cell Lung Cancer Cells with Epidermal Growth Factor ReceptorL858R Mutation through Mitochondrial Oxidative Phosphorylation-Dependent Activation of BAX and BAK

Investigators Look Past Standard Immunotherapy for Additional Lung Cancer Solutions: "That's the beauty of science. Anything can be intellectual."

Targeting Angiogenesis in Squamous Non-Small Cell Lung Cancer

Structure-Based Design of a New Bisintercalating Anthracycline Antibiotic

Intercalation of erlotinib and pemetrexed in the treatment of non-small cell lung cancer

Erlotinib, an Effective Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Induces p27KIP1 Up-Regulation and Nuclear Translocation in Association with Cell Growth Inhibition and G1/S Phase Arrest in Human Non-Small-Cell Lung Cancer Cell Lines

Nanoparticle albumin bound-paclitaxel for treatment of advanced non-small cell lung cancer: an evaluation of the clinical evidence

Role of Erlotinib in the Treatment of Non-Small Cell Lung Cancer: Clinical Outcomes in Wild-Type Epidermal Growth Factor Receptor Patients

Indirect measurements of differential gene expression with cDNA microarrays

Abstract 4748: RICTOR signaling modulates the activity of EGFR tyrosine kinase inhibitors (TKI) in EGFR -mutated non-small cell lung cancer (NSCLC)

Abstract 2740: MET exon 14 skipping mutation promotes metastasis via activation of the PI3K/Akt-Rac1 pathway in non-small cell lung cancer

Abstract 4907: A novel functional analysis of MET exon 14 skipping mutation in regulation of tumor cell invasion and metastasis

Abstract 589: DNA demethylating agent and histone deacetylation inhibitor synergistically induce paired box 5 gene expression in non-small cell lung cancer cell lines

Targeting the PI3K/AKT/mTOR pathway: potential for lung cancer treatment

Abstract 1017: RICTOR/mTOR signaling regulates novel immune checkpoints in non-small cell lung cancer (NSCLC)

RICTOR amplification as a novel therapeutic target for lung cancer brain metastases

Abstract 1217: Blockade of Aurora kinase A synergizes with platinum and radiation in non-small cell lung cancer cells

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