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Dysfunction of the RET receptor in human cancer

Cellular and molecular life sciences : CMLS, 2004-12, Vol.61 (23), p.2954-2964

2004

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Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade

Molecular and Cellular Biology, 2001-07, Vol.21 (13), p.4177-4187

2001

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Critical Role of the HMGI(Y) Proteins in Adipocytic Cell Growth and Differentiation

Molecular and Cellular Biology, 2001-04, Vol.21 (7), p.2485-2495

2001

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A New Germline RET Mutation Apparently Devoid of Transforming Activity Serendipitously Discovered in a Patient with Atrophic Autoimmune Thyroiditis and Primary Ovarian Failure

The journal of clinical endocrinology and metabolism, 2004-10, Vol.89 (10), p.4810-4816

2004

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Molecular heterogeneity of RET loss of function in Hirschsprung's disease

The EMBO journal, 1996-06, Vol.15 (11), p.2717-2725

1996

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Molecular defects in thyroid carcinomas: role of the RET oncogene in thyroid neoplastic transformation

European journal of endocrinology, 1995-11, Vol.133 (5), p.513

1995

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The ret/ptc1 oncogene is activated in familial adenomatous polyposis-associated thyroid papillary carcinomas

The journal of clinical endocrinology and metabolism, 1998-03, Vol.83 (3), p.1003-1006

1998

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Molecular biology of the MEN2 gene

Journal of internal medicine, 1998-06, Vol.243 (6), p.505-508

1998

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Molecular mechanisms of RET activation in human neoplasia

Journal of endocrinological investigation, 1999-11, Vol.22 (10), p.811-819

1999

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The Neuron-Specific Rai (ShcC) Adaptor Protein Inhibits Apoptosis by Coupling Ret to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway

Molecular and Cellular Biology, 2002-10, Vol.22 (20), p.7351-7363

2002

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PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

Cell, 1990-02, Vol.60 (4), p.557-563

1990

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Genetic alterations in differentiated thyroid cancer: what can be expected for gene expression profiling of thyroid carcinomas

Annales d'endocrinologie, 2003-02, Vol.64 (1), p.62-63

2003

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Positive and negative regulation of cell proliferation by E2F-1: influence of protein level and human papillomavirus oncoproteins

Molecular and Cellular Biology, 1994-12, Vol.14 (12), p.8241-8249

1994

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Oncogenic protein tyrosine kinases: Dysfunction of the RET receptor in human cancer

Cellular and molecular life sciences : CMLS, 2004-12, Vol.61 (23), p.2954-2964

2004

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Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins

The journal of clinical endocrinology and metabolism, 2000-10, Vol.85 (10), p.3898-3907

2000

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

Nature medicine, 2002-10, Vol.8 (10), p.1136-1144

2002

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Minireview: RET: Normal and Abnormal Functions

Endocrinology (Philadelphia), 2004-12, Vol.145 (12), p.5448-5451

2004

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RET/PTC activation in human thyroid carcinomas

Journal of endocrinological investigation, 1995-02, Vol.18 (2), p.127-129

1995

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Different mutations of the RET gene cause different human tumoral diseases

Biochimie, 1999-04, Vol.81 (4), p.397-402

1999

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The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line

Cell growth & differentiation, 1993-02, Vol.4 (2), p.77-84

1993

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Activation of the Erk8 Mitogen-activated Protein (MAP) Kinase by RET/PTC3, a Constitutively Active Form of the RET Proto-oncogene

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.10567-10576

2006

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Efficient Inhibition of RET/Papillary Thyroid Carcinoma Oncogenic Kinases by 4-Amino-5-(4-Chloro-Phenyl)-7-(t-Butyl)Pyrazolo[3,4-d]Pyrimidine (PP2)

The journal of clinical endocrinology and metabolism, 2003-04, Vol.88 (4), p.1897-1902

2003

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Osteopontin Is Overexpressed in Human Papillary Thyroid Carcinomas and Enhances Thyroid Carcinoma Cell Invasiveness

The journal of clinical endocrinology and metabolism, 2005-09, Vol.90 (9), p.5270-5278

2005

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Expression of the RET/PTC1 oncogene impairs the activity of TTF-1 and Pax-8 thyroid transcription factors

Cell growth & differentiation, 1998, Vol.9 (1), p.97-103

1998

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Potent Mitogenicity of the RET/PTC3 Oncogene Correlates with Its Prevalence in Tall-Cell Variant of Papillary Thyroid Carcinoma

The American journal of pathology, 2002, Vol.160 (1), p.247-254

2002

Volltextzugriff (PDF)

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Dysfunction of the RET receptor in human cancer

Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade

Critical Role of the HMGI(Y) Proteins in Adipocytic Cell Growth and Differentiation

A New Germline RET Mutation Apparently Devoid of Transforming Activity Serendipitously Discovered in a Patient with Atrophic Autoimmune Thyroiditis and Primary Ovarian Failure

Molecular heterogeneity of RET loss of function in Hirschsprung's disease

Molecular defects in thyroid carcinomas: role of the RET oncogene in thyroid neoplastic transformation

The ret/ptc1 oncogene is activated in familial adenomatous polyposis-associated thyroid papillary carcinomas

Molecular biology of the MEN2 gene

Molecular mechanisms of RET activation in human neoplasia

The Neuron-Specific Rai (ShcC) Adaptor Protein Inhibits Apoptosis by Coupling Ret to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

Genetic alterations in differentiated thyroid cancer: what can be expected for gene expression profiling of thyroid carcinomas

Positive and negative regulation of cell proliferation by E2F-1: influence of protein level and human papillomavirus oncoproteins

Oncogenic protein tyrosine kinases: Dysfunction of the RET receptor in human cancer

Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

Minireview: RET: Normal and Abnormal Functions

RET/PTC activation in human thyroid carcinomas

Different mutations of the RET gene cause different human tumoral diseases

The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line

Activation of the Erk8 Mitogen-activated Protein (MAP) Kinase by RET/PTC3, a Constitutively Active Form of the RET Proto-oncogene

Efficient Inhibition of RET/Papillary Thyroid Carcinoma Oncogenic Kinases by 4-Amino-5-(4-Chloro-Phenyl)-7-(t-Butyl)Pyrazolo[3,4-d]Pyrimidine (PP2)

Osteopontin Is Overexpressed in Human Papillary Thyroid Carcinomas and Enhances Thyroid Carcinoma Cell Invasiveness

Expression of the RET/PTC1 oncogene impairs the activity of TTF-1 and Pax-8 thyroid transcription factors

Potent Mitogenicity of the RET/PTC3 Oncogene Correlates with Its Prevalence in Tall-Cell Variant of Papillary Thyroid Carcinoma

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