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A microfluidics platform for combinatorial drug screening on cancer biopsies

Nature communications, 2018-06, Vol.9 (1), p.2434-13, Article 2434

2018

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Phenotypic screening in cancer drug discovery - past, present and future

Nature reviews. Drug discovery, 2014-08, Vol.13 (8), p.588-602

2014

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Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers

Cancer research (Chicago, Ill.), 2021-04, Vol.81 (7), p.1627-1632

2021

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Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids

Nature communications, 2020-10, Vol.11 (1), p.5271-5271, Article 5271

2020

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Reproducible pharmacogenomic profiling of cancer cell line panels

Nature (London), 2016-05, Vol.533 (7603), p.333-337

2016

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CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds

PloS one, 2018-01, Vol.13 (1), p.e0191838-e0191838

2018

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An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors

Science translational medicine, 2015-04, Vol.7 (284), p.284ra57

2015

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Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening

Scientific reports, 2021-01, Vol.11 (1), p.372-372, Article 372

2021

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US cancer institute to overhaul tumour cell lines

Nature (London), 2016-02, Vol.530 (7591), p.391-391

Ledford, Heidi

2016

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Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate

Nature biotechnology, 2016-11, Vol.34 (11), p.1161-1167

2016

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Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments

Scientific reports, 2020-05, Vol.10 (1), p.7653-7653, Article 7653

2020

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Comparison of Drug Inhibitory Effects (IC50) in Monolayer and Spheroid Cultures

Bulletin of mathematical biology, 2020-06, Vol.82 (6), p.68-68, Article 68

2020

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Microfluidic co-culture system for cancer migratory analysis and anti-metastatic drugs screening

Scientific reports, 2016-10, Vol.6 (1), p.35544-35544, Article 35544

2016

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Optimization of liquid overlay technique to formulate heterogenic 3D co-cultures models

Biotechnology and bioengineering, 2014-08, Vol.111 (8), p.1672-1685

2014

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A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments

Scientific reports, 2019-07, Vol.9 (1), p.10120-9, Article 10120

2019

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Drug Discovery Goes Three-Dimensional: Goodbye to Flat High-Throughput Screening?

Assay and drug development technologies, 2015-06, Vol.13 (5), p.262

2015

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Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models

Cell reports (Cambridge), 2021-10, Vol.37 (1), p.109788-109788, Article 109788

2021

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Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer Model

Scientific reports, 2017-10, Vol.7 (1), p.14167-14, Article 14167

2017

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A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening

Experimental biology and medicine (Maywood, N.J.), 2014-09, Vol.239 (9), p.1240-1254

2014

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Influence of a three-dimensional, microarray environment on human Cell culture in drug screening systems

Biomaterials, 2012-12, Vol.33 (35), p.9087-9096

2012

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A microphysiological system model of therapy for liver micrometastases

Experimental biology and medicine (Maywood, N.J.), 2014-09, Vol.239 (9), p.1170-1179

2014

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Alginate core-shell beads for simplified three-dimensional tumor spheroid culture and drug screening

Biomedical microdevices, 2015-04, Vol.17 (2), p.33-9, Article 33

2015

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Proteomic Profiling of the NCI-60 Cancer Cell Lines Using New High-Density Reverse-Phase Lysate Microarrays

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (24), p.14229-14234

2003

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A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids

Biomaterials, 2010-11, Vol.31 (32), p.8436-8444

2010

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A growth model of neuroendocrine tumor surrogates and the efficacy of a novel somatostatin-receptor–guided antibody-drug conjugate: Perspectives on clinical response?

Surgery, 2020-01, Vol.167 (1), p.197-203

2020

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A microfluidics platform for combinatorial drug screening on cancer biopsies

Phenotypic screening in cancer drug discovery - past, present and future

Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers

Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids

Reproducible pharmacogenomic profiling of cancer cell line panels

CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds

An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors

Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening

US cancer institute to overhaul tumour cell lines

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate

Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments

Comparison of Drug Inhibitory Effects (IC50) in Monolayer and Spheroid Cultures

Microfluidic co-culture system for cancer migratory analysis and anti-metastatic drugs screening

Optimization of liquid overlay technique to formulate heterogenic 3D co-cultures models

A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments

Drug Discovery Goes Three-Dimensional: Goodbye to Flat High-Throughput Screening?

Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models

Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer Model

A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening

Influence of a three-dimensional, microarray environment on human Cell culture in drug screening systems

A microphysiological system model of therapy for liver micrometastases

Alginate core-shell beads for simplified three-dimensional tumor spheroid culture and drug screening

Proteomic Profiling of the NCI-60 Cancer Cell Lines Using New High-Density Reverse-Phase Lysate Microarrays

A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids

A growth model of neuroendocrine tumor surrogates and the efficacy of a novel somatostatin-receptor–guided antibody-drug conjugate: Perspectives on clinical response?

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