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Structure-activity relationships of GPR120 agonists based on a docking simulation

Molecular pharmacology, 2010-11, Vol.78 (5), p.804-810

2010

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An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake

Cell reports (Cambridge), 2024-07, Vol.43 (7), p.114509, Article 114509

2024

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Activation of GPR120 by TUG891 ameliorated cisplatin-induced acute kidney injury via repressing ER stress and apoptosis

Biomedicine & pharmacotherapy, 2020-06, Vol.126, p.110056, Article 110056

2020

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Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma

Oncogene, 2013-12, Vol.32 (49), p.5541-5550

2013

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α-linolenic acid mitigates microglia-mediated neuroinflammation of schizophrenia in mice by suppressing the NF-κB/NLRP3 pathway via binding GPR120-β-arrestin 2

International immunopharmacology, 2024-12, Vol.142 (Pt A), p.113047, Article 113047

2024

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Free fatty acid receptor 4 (FFA4) activation attenuates obese asthma by suppressing adiposity and resolving metaflammation

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116509-116509, Article 116509

2024

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A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

Biomedicine & pharmacotherapy, 2021-07, Vol.139, p.111613-111613, Article 111613

2021

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Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy

Acta pharmacologica Sinica, 2021-02, Vol.42 (2), p.252-263

2021

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Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells

Biochemical and biophysical research communications, 2015-09, Vol.465 (3), p.512-515

2015

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Free Fatty Acid 4 Receptor Activation Attenuates Collagen-Induced Arthritis by Rebalancing Th1/Th17 and Treg Cells

International journal of molecular sciences, 2024-06, Vol.25 (11), p.5866

2024

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N-3 Polyunsaturated Fatty Acids Protect against Alcoholic Liver Steatosis by Activating FFA4 in Kupffer Cells

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5476

2024

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GPR120 controls neonatal brown adipose tissue thermogenic induction

American journal of physiology: endocrinology and metabolism, 2019-11, Vol.317 (5), p.E742-E750

2019

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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Molecular metabolism (Germany), 2021-03, Vol.45, p.101166-101166, Article 101166

2021

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Omega-3 fatty acids are protective in hepatic ischemia reperfusion injury in the absence of GPR120 signaling

Journal of pediatric surgery, 2019-11, Vol.54 (11), p.2392-2397

2019

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Free fatty acids induce cholecystokinin secretion through GPR120

Naunyn-Schmiedeberg's archives of pharmacology, 2008-06, Vol.377 (4-6), p.523-527

2008

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Long noncoding RNA LINC00662‐miR‐15b‐5p mediated GPR120 dysregulation contributes to osteoarthritis

Pathology international, 2020-03, Vol.70 (3), p.155-165

2020

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Eicosapentaenoic acid prevents the progression of intracranial aneurysms in rats

Journal of neuroinflammation, 2020-04, Vol.17 (1), p.129-129, Article 129

2020

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Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: relationships with body mass index

American journal of physiology: Gastrointestinal and liver physiology, 2014-11, Vol.307 (10), p.G958-G967

2014

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Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

Molecular metabolism (Germany), 2020-12, Vol.42, p.101103-101103, Article 101103

2020

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ω-3 Polyunsaturated fatty acids accelerate airway repair by activating FFA4 in club cells

American journal of physiology. Lung cellular and molecular physiology, 2017-06, Vol.312 (6), p.L835-L844

2017

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Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (5), p.1278-1283

2017

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Protective effects of GPR120 agonist-programmed macrophages on renal interstitial fibrosis in unilateral ureteral obstruction (UUO) rats

Biomedicine & pharmacotherapy, 2019-09, Vol.117, p.109172-109172, Article 109172

2019

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Improving metabolic stability with deuterium: The discovery of GPU-028, a potent free fatty acid receptor 4 agonists

Bioorganic & medicinal chemistry, 2017-12, Vol.25 (24), p.6647-6652

2017

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Topical Docosahexaenoic Acid (DHA) Accelerates Skin Wound Healing in Rats and Activates GPR120

Biological research for nursing, 2016-07, Vol.18 (4), p.411-419

2016

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Fish oil and flax seed oil supplemented diets increase FFAR4 expression in the rat colon

Inflammation research, 2015-10, Vol.64 (10), p.809-815

2015

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Structure-activity relationships of GPR120 agonists based on a docking simulation

An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake

Activation of GPR120 by TUG891 ameliorated cisplatin-induced acute kidney injury via repressing ER stress and apoptosis

Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma

α-linolenic acid mitigates microglia-mediated neuroinflammation of schizophrenia in mice by suppressing the NF-κB/NLRP3 pathway via binding GPR120-β-arrestin 2

Free fatty acid receptor 4 (FFA4) activation attenuates obese asthma by suppressing adiposity and resolving metaflammation

A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy

Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells

Free Fatty Acid 4 Receptor Activation Attenuates Collagen-Induced Arthritis by Rebalancing Th1/Th17 and Treg Cells

N-3 Polyunsaturated Fatty Acids Protect against Alcoholic Liver Steatosis by Activating FFA4 in Kupffer Cells

GPR120 controls neonatal brown adipose tissue thermogenic induction

Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Omega-3 fatty acids are protective in hepatic ischemia reperfusion injury in the absence of GPR120 signaling

Free fatty acids induce cholecystokinin secretion through GPR120

Long noncoding RNA LINC00662‐miR‐15b‐5p mediated GPR120 dysregulation contributes to osteoarthritis

Eicosapentaenoic acid prevents the progression of intracranial aneurysms in rats

Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: relationships with body mass index

Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

ω-3 Polyunsaturated fatty acids accelerate airway repair by activating FFA4 in club cells

Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist

Protective effects of GPR120 agonist-programmed macrophages on renal interstitial fibrosis in unilateral ureteral obstruction (UUO) rats

Improving metabolic stability with deuterium: The discovery of GPU-028, a potent free fatty acid receptor 4 agonists

Topical Docosahexaenoic Acid (DHA) Accelerates Skin Wound Healing in Rats and Activates GPR120

Fish oil and flax seed oil supplemented diets increase FFAR4 expression in the rat colon

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