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Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts

Circulation (New York, N.Y.), 2000-02, Vol.101 (5), p.510-515

2000

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Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

Nature (London), 1998-03, Vol.392 (6673), p.293-296

1998

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The common SCN5A mutation R1193Q causes LQTS-type electrophysiological alterations of the cardiac sodium channel

Journal of medical genetics, 2004-05, Vol.41 (5), p.e66-e66

2004

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Multiple mechanisms of Na+ channel-linked long-QT syndrome

Circulation research, 1996-05, Vol.78 (5), p.916-924

1996

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Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes

American journal of physiology. Heart and circulatory physiology, 1990-09, Vol.259 (3), p.H820-H826

1990

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Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 alpha -subunits

American Journal of Physiology: Cell Physiology, 1998-06, Vol.274 (6), p.C1501-C1510

1998

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Mechanism of lidocaine block of late current in long Q-T mutant Na+ channels

American journal of physiology. Heart and circulatory physiology, 1998-02, Vol.274 (2), p.H477-H487

1998

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Effects of III-IV Linker Mutations on Human Heart Na+ Channel Inactivation Gating

Circulation research, 1994-07, Vol.75 (1), p.114-122

1994

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Exchange of Conduction Pathways Between Two Related K$^+$ Channels

Science (American Association for the Advancement of Science), 1991-02, Vol.251 (4996), p.942-944

1991

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Gating-dependent mechanism of 4-aminopyridine block in two related potassium channels

The Journal of general physiology, 1993-11, Vol.102 (5), p.797-816

1993

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Mutational analysis of ion conduction and drug binding sites in the inner mouth of voltage-gated K+ channels

Biophysical journal, 1994-12, Vol.67 (6), p.2316-2325

1994

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beta $-Adrenergic Inhibition of Cardiac Sodium Channels by Dual G-Protein Pathways

Science (American Association for the Advancement of Science), 1989-08, Vol.245 (4917), p.516-519

1989

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Inactivation determined by a single site in K+ pores

Pflügers Archiv, 1993, Vol.422 (4), p.354-363

1993

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Hysteresis effect implicates calcium cycling as a mechanism of repolarization alternans

Circulation (New York, N.Y.), 2003-11, Vol.108 (21), p.2704-2709

2003

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U-Type Inactivation of Kv3.1 and Shaker Potassium Channels

Biophysical journal, 2001-08, Vol.81 (2), p.814-826

2001

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Patterns of internal and external tetraethylammonium block in four homologous K+ channels

Molecular pharmacology, 1991-08, Vol.40 (2), p.299-307

1991

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Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore

Biophysical journal, 1993-09, Vol.65 (3), p.1235-1242

1993

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Ion channel defects in cardiac arrhythmia

The Journal of membrane biology, 1999-08, Vol.170 (3), p.181-190

Kirsch, G E

1999

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Internal and external TEA block in single cloned K+ channels

American Journal of Physiology: Cell Physiology, 1991-10, Vol.261 (4), p.C583-C590

1991

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Functional role of a conserved aspartate in the external mouth of voltage-gated potassium channels

Biophysical journal, 1995-05, Vol.68 (5), p.1804-1813

1995

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A single nonpolar residue in the deep pore of related K+ channels acts as a K+:Rb+ conductance switch

Biophysical journal, 1992-04, Vol.62 (1), p.136-144

1992

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Inhibition of cardiac Na+ currents by isoproterenol

American journal of physiology. Heart and circulatory physiology, 1990-04, Vol.258 (4), p.H977-H982

1990

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Inactivation of Kv2.1 Potassium Channels

Biophysical journal, 1998-04, Vol.74 (4), p.1779-1789

1998

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Multiple residues specify external tetraethylammonium blockade in voltage-gated potassium channels

Biophysical journal, 1995-08, Vol.69 (2), p.428-434

1995

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Changes in Sodium Channel Gating Produced by Point Mutations in a Cytoplasmic Linker

Science (American Association for the Advancement of Science), 1990-11, Vol.250 (4981), p.688-691

1990

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Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

The common SCN5A mutation R1193Q causes LQTS-type electrophysiological alterations of the cardiac sodium channel

Multiple mechanisms of Na+ channel-linked long-QT syndrome

Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes

Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 alpha -subunits

Mechanism of lidocaine block of late current in long Q-T mutant Na+ channels

Effects of III-IV Linker Mutations on Human Heart Na+ Channel Inactivation Gating

Exchange of Conduction Pathways Between Two Related K$^+$ Channels

Gating-dependent mechanism of 4-aminopyridine block in two related potassium channels

Mutational analysis of ion conduction and drug binding sites in the inner mouth of voltage-gated K+ channels

beta $-Adrenergic Inhibition of Cardiac Sodium Channels by Dual G-Protein Pathways

Inactivation determined by a single site in K+ pores

Hysteresis effect implicates calcium cycling as a mechanism of repolarization alternans

U-Type Inactivation of Kv3.1 and Shaker Potassium Channels

Patterns of internal and external tetraethylammonium block in four homologous K+ channels

Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore

Ion channel defects in cardiac arrhythmia

Internal and external TEA block in single cloned K+ channels

Functional role of a conserved aspartate in the external mouth of voltage-gated potassium channels

A single nonpolar residue in the deep pore of related K+ channels acts as a K+:Rb+ conductance switch

Inhibition of cardiac Na+ currents by isoproterenol

Inactivation of Kv2.1 Potassium Channels

Multiple residues specify external tetraethylammonium blockade in voltage-gated potassium channels

Changes in Sodium Channel Gating Produced by Point Mutations in a Cytoplasmic Linker

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