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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

International journal of molecular sciences, 2019-01, Vol.20 (1), p.81

2019

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Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease

Nature communications, 2021-06, Vol.12 (1), p.3416-18, Article 3416

2021

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Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12550

2023

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APOEε4 and risk of Alzheimer's disease - time to move forward

Frontiers in neuroscience, 2023-05, Vol.17, p.1195724-1195724

2023

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Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic

PloS one, 2013-02, Vol.8 (2), p.e53478

2013

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Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice

Scientific reports, 2017-06, Vol.7 (1), p.4307-13, Article 4307

2017

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Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

PloS one, 2017-02, Vol.12 (2), p.e0172161-e0172161

2017

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Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice

Toxicology reports, 2022-01, Vol.9, p.393-403

2022

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Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease

British journal of pharmacology, 2019-09, Vol.176 (18), p.3599-3610

2019

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Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Biochemical pharmacology, 2010-05, Vol.79 (9), p.1310-1316

2010

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Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

The Journal of biological chemistry, 2010-11, Vol.285 (47), p.36945-36957

2010

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RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

Scientific reports, 2016-04, Vol.6 (1), p.24048-24048, Article 24048

2016

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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924

2013

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Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice

Biochimica et biophysica acta. Molecular basis of disease, 2018-01, Vol.1864 (1), p.152-161

2018

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Apolipoprotein E4 (APOE4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease

Molecular & cellular proteomics, 2016-07, Vol.15 (7), p.2252-2262

2016

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HIGH-FAT DIET AFFECTS INFLAMMATION AND INCREASES TREM2 LEVEL IN APP MICE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P655-P655

2016

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IMPACT OF APOE POLYMORPHISMS ON AMYLOID-BETA OLIGOMERIZATION AND ASSOCIATED COGNITIVE DECLINE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P1038-P1039

2016

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Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-92c

2013

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snoRNAs in plasma extracellular vesicles of AD patients are differentially associated with APOE genotype

Alzheimer's & dementia, 2021-12, Vol.17 (S4), p.n/a

2021

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Neural responses to peripheral infection in Alzheimer’s disease model mice

Alzheimer's & dementia, 2023-12, Vol.19 (S13)

2023

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Sex‐specific decoupling of cerebral blood flow and glucose metabolism in Alzheimer’s disease mouse model

Alzheimer's & dementia, 2022-12, Vol.18 (S6), p.n/a

2022

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Sex‐specific cerebral blood flow trajectories in mouse models of Alzheimer’s disease

Alzheimer's & dementia, 2021-12, Vol.17 (S4), p.n/a

2021

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Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4: Molecular and cell biology/neuroinflammation

Alzheimer's & dementia, 2020-12, Vol.16 (S2)

2020

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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924

2013

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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease

Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

APOEε4 and risk of Alzheimer's disease - time to move forward

Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic

Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice

Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice

Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease

Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice

Apolipoprotein E4 (APOE4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease

HIGH-FAT DIET AFFECTS INFLAMMATION AND INCREASES TREM2 LEVEL IN APP MICE

IMPACT OF APOE POLYMORPHISMS ON AMYLOID-BETA OLIGOMERIZATION AND ASSOCIATED COGNITIVE DECLINE

Comment on: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

snoRNAs in plasma extracellular vesicles of AD patients are differentially associated with APOE genotype

Neural responses to peripheral infection in Alzheimer’s disease model mice

Sex‐specific decoupling of cerebral blood flow and glucose metabolism in Alzheimer’s disease mouse model

Sex‐specific cerebral blood flow trajectories in mouse models of Alzheimer’s disease

Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4

Role of TREM2 deficiency in Alzheimer’s disease model mice expressing human APOE3 or APOE4: Molecular and cell biology/neuroinflammation

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

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