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Impaired B‐cell tolerance checkpoints promote the development of autoimmune diseases and pathogenic autoantibodies

Immunological reviews, 2019-11, Vol.292 (1), p.90-101

2019

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Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data

Frontiers in immunology, 2019-02, Vol.10, p.129-129

2019

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The House of Hemp and Butter: A History of Old Riga

Kevin C. O'Connor

1, 2019

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Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein

Nature medicine, 2007-02, Vol.13 (2), p.211-217

2007

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Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis

The Journal of immunology (1950), 2009-09, Vol.183 (6), p.4067-4076

2009

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Traumatic spinal cord injury in the United States, 1993-2012

JAMA : the journal of the American Medical Association, 2015-06, Vol.313 (22), p.2236

2015

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pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires

Bioinformatics (Oxford, England), 2014-07, Vol.30 (13), p.1930-1932

2014

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Comprehensive serological profiling of human populations using a synthetic human virome

Science (American Association for the Advancement of Science), 2015-06, Vol.348 (6239), p.1105-1105

2015

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Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.12468-12473

2015

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Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology

Frontiers in immunology, 2020-05, Vol.11, p.776-776

2020

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Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

Nature biotechnology, 2023-09, Vol.41 (9), p.1229-1238

2023

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The B cell immunobiology that underlies CNS autoantibody-mediated diseases

Nature reviews. Neurology, 2020-09, Vol.16 (9), p.481

2020

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Myasthenia gravis complement activity is independent of autoantibody titer and disease severity

PloS one, 2022-03, Vol.17 (3), p.e0264489-e0264489

2022

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B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

Science translational medicine, 2014-08, Vol.6 (248), p.248ra107

2014

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Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing

The Journal of immunology (1950), 2017-02, Vol.198 (4), p.1460-1473

2017

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Durability of the Rituximab Response in Acetylcholine Receptor Autoantibody-Positive Myasthenia Gravis

JAMA neurology, 2017-01, Vol.74 (1), p.60

2017

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Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (48), p.30649-30660

2020

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Evaluation of KIR4.1 as an Immune Target in Multiple Sclerosis

The New England journal of medicine, 2016-04, Vol.374 (15), p.1495-1496

2016

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Specific peripheral B cell tolerance defects in patients with multiple sclerosis

The Journal of clinical investigation, 2013-06, Vol.123 (6), p.2737-2741

2013

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Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production

The Journal of immunology (1950), 2016-03, Vol.196 (5), p.2075-2084

2016

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CD4+ follicular regulatory T cells optimize the influenza virus-specific B cell response

The Journal of experimental medicine, 2021-03, Vol.218 (3)

2021

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Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis

The Journal of experimental medicine, 2020-12, Vol.217 (12)

2020

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A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data

The Journal of immunology (1950), 2016-11, Vol.197 (9), p.3566-3574

2016

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Cortical injury in multiple sclerosis; the role of the immune system

BMC neurology, 2011-12, Vol.11 (1), p.152-152, Article 152

2011

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Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD - CD27 - Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients

The Journal of immunology (1950), 2019-09, Vol.203 (6), p.1650-1664

2019

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Impaired B‐cell tolerance checkpoints promote the development of autoimmune diseases and pathogenic autoantibodies

Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data

The House of Hemp and Butter: A History of Old Riga

Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein

Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis

Traumatic spinal cord injury in the United States, 1993-2012

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires

Comprehensive serological profiling of human populations using a synthetic human virome

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology

Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

The B cell immunobiology that underlies CNS autoantibody-mediated diseases

Myasthenia gravis complement activity is independent of autoantibody titer and disease severity

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing

Durability of the Rituximab Response in Acetylcholine Receptor Autoantibody-Positive Myasthenia Gravis

Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis

Evaluation of KIR4.1 as an Immune Target in Multiple Sclerosis

Specific peripheral B cell tolerance defects in patients with multiple sclerosis

Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production

CD4+ follicular regulatory T cells optimize the influenza virus-specific B cell response

Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis

A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data

Cortical injury in multiple sclerosis; the role of the immune system

Phenotypic and Ig Repertoire Analyses Indicate a Common Origin of IgD - CD27 - Double Negative B Cells in Healthy Individuals and Multiple Sclerosis Patients

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