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Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate

Cell reports (Cambridge), 2021-01, Vol.34 (1), p.108588-108588, Article 108588

2021

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cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons

Experimental neurology, 2020-07, Vol.329, p.113252-113252, Article 113252

2020

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Studies to Assess the Utility of Serum Neurofilament Light Chain as a Biomarker in Chemotherapy-Induced Peripheral Neuropathy

Cancers, 2023-08, Vol.15 (17), p.4216

2023

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Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury

The European journal of neuroscience, 2005-08, Vol.22 (3), p.587-594

2005

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D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons

Science (American Association for the Advancement of Science), 1990-12, Vol.250 (4986), p.1429-1432

1990

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Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy

The Journal of clinical investigation, 2003-02, Vol.111 (4), p.507-514

2003

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NMDA receptor blockade reverses motor response alterations induced by levodopa

Neuroreport, 1994-12, Vol.5 (18), p.2586-2588

1994

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Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Journal of pharmaceutical sciences, 2002-02, Vol.91 (2), p.371-387

2002

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Motor response complications and the function of striatal efferent systems

Neurology, 1993-12, Vol.43 (12 Suppl 6), p.S23

1993

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First Synthesis of Piperazine-derived [1,2,4]Triazolo[1,5-a]pyrazine as an Adenosine A2A Receptor Antagonist

Heterocycles, 2005-10, Vol.65 (10), p.2321

2005

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Substance P increases release of acetylcholine in the dorsal striatum of freely moving rats

Brain research, 1993-10, Vol.623 (2), p.189-194

1993

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Synthesis of alkyne derivatives of a novel triazolopyrazine as A 2A adenosine receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.511-515

2005

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GABAA and GABAB receptors differentially regulate striatal acetylcholine release in vivo

Neuroscience letters, 1993-10, Vol.160 (2), p.126-130

1993

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Synthesis of alkyne derivatives of a novel triazolopyrazine as A(2A) adenosine receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.511-515

2005

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Identification of insulin-like growth factor binding protein-2 as a biochemical surrogate marker for the in vivo effects of recombinant human insulin-like growth factor-1 in mice

The Journal of pharmacology and experimental therapeutics, 1997-04, Vol.281 (1), p.522

1997

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Region‐Specific Targets of p42/p44MAPK Signaling in Rat Brain

Journal of neurochemistry, 1998-02, Vol.70 (2), p.558-571

1998

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Reversal of levodopa-induced motor fluctuations in experimental parkinsonism by NMDA receptor blockade

Brain research, 1995-12, Vol.701 (1), p.13-18

1995

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Controls for Lesions of the Nigrostriatal Dopamine System

Science (American Association for the Advancement of Science), 1991-07, Vol.253 (5017), p.332-332

1991

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Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats

Brain research, 1991-06, Vol.552 (1), p.113-118

1991

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Dopaminergic modulation of striatal neuropeptides : differential effects of D1 and D2 receptor stimulation on somatostatin, neuropeptide Y, neurotensin, dynorphin and enkephalin

Brain research, 1992-05, Vol.581 (2), p.261-268

1992

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Continuous and intermittent levodopa differentially affect basal ganglia function

Annals of neurology, 1989-05, Vol.25 (5), p.473-478

1989

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Novel Bicyclic Piperazine Derivatives of Triazolotriazine and Triazolopyrimidines as Highly Potent and Selective Adenosine A 2 A Receptor Antagonists

Journal of medicinal chemistry, 2004-12, Vol.47 (25), p.6218-6229

2004

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Differential effect of subthalamic nucleus ablation on dopamine D1 and D2 agonist-induced rotation in 6-hydroxydopamine-lesioned rats

Brain research, 1992-08, Vol.588 (2), p.307-310

1992

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Chronic levodopa treatment alters basal and dopamine agonist-stimulated cerebral glucose utilization

The Journal of neuroscience, 1990-12, Vol.10 (12), p.3889-3895

1990

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Effects of kappa receptor agonists on D1 and D2 dopamine agonist and antagonist-induced behaviors

Psychopharmacologia, 1996, Vol.123 (2), p.215-221

1996

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Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate

cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons

Studies to Assess the Utility of Serum Neurofilament Light Chain as a Biomarker in Chemotherapy-Induced Peripheral Neuropathy

Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury

D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons

Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy

NMDA receptor blockade reverses motor response alterations induced by levodopa

Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Motor response complications and the function of striatal efferent systems

First Synthesis of Piperazine-derived [1,2,4]Triazolo[1,5-a]pyrazine as an Adenosine A2A Receptor Antagonist

Substance P increases release of acetylcholine in the dorsal striatum of freely moving rats

Synthesis of alkyne derivatives of a novel triazolopyrazine as A 2A adenosine receptor antagonists

GABAA and GABAB receptors differentially regulate striatal acetylcholine release in vivo

Synthesis of alkyne derivatives of a novel triazolopyrazine as A(2A) adenosine receptor antagonists

Identification of insulin-like growth factor binding protein-2 as a biochemical surrogate marker for the in vivo effects of recombinant human insulin-like growth factor-1 in mice

Region‐Specific Targets of p42/p44MAPK Signaling in Rat Brain

Reversal of levodopa-induced motor fluctuations in experimental parkinsonism by NMDA receptor blockade

Controls for Lesions of the Nigrostriatal Dopamine System

Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats

Dopaminergic modulation of striatal neuropeptides : differential effects of D1 and D2 receptor stimulation on somatostatin, neuropeptide Y, neurotensin, dynorphin and enkephalin

Continuous and intermittent levodopa differentially affect basal ganglia function

Novel Bicyclic Piperazine Derivatives of Triazolotriazine and Triazolopyrimidines as Highly Potent and Selective Adenosine A 2 A Receptor Antagonists

Differential effect of subthalamic nucleus ablation on dopamine D1 and D2 agonist-induced rotation in 6-hydroxydopamine-lesioned rats

Chronic levodopa treatment alters basal and dopamine agonist-stimulated cerebral glucose utilization

Effects of kappa receptor agonists on D1 and D2 dopamine agonist and antagonist-induced behaviors

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