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PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo

Clinical pharmacology and therapeutics, 2012-06, Vol.91 (6), p.1044-1052

2012

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The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study

European journal of pharmacology, 2010-01, Vol.626 (2), p.171-178

2010

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Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment‐resistant bipolar depression

British journal of clinical pharmacology, 2012-08, Vol.74 (2), p.304-314

2012

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In vitro–in vivo extrapolation of CYP2C8-catalyzed paclitaxel 6α-hydroxylation: effects of albumin on in vitro kinetic parameters and assessment of interindividual variability in predicted clearance

European journal of clinical pharmacology, 2011-08, Vol.67 (8), p.815-824

2011

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Metabolism of melatonin by human cytochromes p450

Drug metabolism and disposition, 2005-04, Vol.33 (4), p.489-494

2005

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Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure–activity relationship

Biochemical pharmacology, 2005-03, Vol.69 (6), p.903-912

2005

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Long-Term Efavirenz Autoinduction and Its Effect on Plasma Exposure in HIV Patients

Clinical pharmacology and therapeutics, 2010-11, Vol.88 (5), p.676-684

2010

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In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver

Journal of pharmaceutical sciences, 2007-02, Vol.96 (2), p.428-437

2007

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Effect of regular organic solvents on cytochrome P450-mediated metabolic activities in rat liver microsomes

Drug metabolism and disposition, 2010-11, Vol.38 (11), p.1922

2010

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Metabolism and excretion of the dipeptidyl peptidase 4 inhibitor [14C]sitagliptin in humans

Drug metabolism and disposition, 2007-04, Vol.35 (4), p.533-538

2007

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Comparative metabolism of cinobufagin in liver microsomes from mouse, rat, dog, minipig, monkey, and human

Drug metabolism and disposition, 2011-04, Vol.39 (4), p.675-682

2011

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A Phase I Study Evaluating Tolerability, Pharmacokinetics, and Preliminary Efficacy of L‐Menthol in Upper Gastrointestinal Endoscopy

Clinical pharmacology and therapeutics, 2011-08, Vol.90 (2), p.221-228

2011

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Effect of Clopidogrel and Ticlopidine on Cytochrome P450 2B6 Activity as Measured by Bupropion Hydroxylation

Clinical pharmacology and therapeutics, 2005-06, Vol.77 (6), p.553-559

2005

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Prediction of human drug-drug interactions from time-dependent inactivation of CYP3A4 in primary hepatocytes using a population-based simulator

Drug metabolism and disposition, 2009-12, Vol.37 (12), p.2330-2339

2009

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Development of a systematic approach to identify metabolites for herbal homologs based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry: gender-related difference in metabolism of Schisandra lignans in rats

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1747

2010

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Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state

Drug metabolism and disposition, 2010-05, Vol.38 (5), p.808-816

2010

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In vivo metabolism study of rhubarb decoction in rat using high-performance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples

Journal of Chromatography A, 2010-11, Vol.1217 (45), p.7144-7152

2010

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Losartan increases bradykinin levels in hypertensive humans

Circulation (New York, N.Y.), 2005-01, Vol.111 (3), p.315-320

2005

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Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6

Drug metabolism and disposition, 2011-05, Vol.39 (5), p.782-788

2011

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Metabolism and excretion of asenapine in healthy male subjects

Drug metabolism and disposition, 2011-04, Vol.39 (4), p.580-590

2011

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Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats

Drug metabolism and disposition, 2009-12, Vol.37 (12), p.2399-2407

2009

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In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2012-08, Vol.67-68, p.175-185

2012

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Screening for in vitro metabolites of Abelmoschus manihot extract in intestinal bacteria by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-12, Vol.879 (32), p.3901-3908

2011

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Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity

European journal of clinical pharmacology, 2013-03, Vol.69 (3), p.507-513

2013

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CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population

European journal of clinical pharmacology, 2012-05, Vol.68 (5), p.637-644

2012

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PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo

The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study

Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment‐resistant bipolar depression

In vitro–in vivo extrapolation of CYP2C8-catalyzed paclitaxel 6α-hydroxylation: effects of albumin on in vitro kinetic parameters and assessment of interindividual variability in predicted clearance

Metabolism of melatonin by human cytochromes p450

Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure–activity relationship

Long-Term Efavirenz Autoinduction and Its Effect on Plasma Exposure in HIV Patients

In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver

Effect of regular organic solvents on cytochrome P450-mediated metabolic activities in rat liver microsomes

Metabolism and excretion of the dipeptidyl peptidase 4 inhibitor [14C]sitagliptin in humans

Comparative metabolism of cinobufagin in liver microsomes from mouse, rat, dog, minipig, monkey, and human

A Phase I Study Evaluating Tolerability, Pharmacokinetics, and Preliminary Efficacy of L‐Menthol in Upper Gastrointestinal Endoscopy

Effect of Clopidogrel and Ticlopidine on Cytochrome P450 2B6 Activity as Measured by Bupropion Hydroxylation

Prediction of human drug-drug interactions from time-dependent inactivation of CYP3A4 in primary hepatocytes using a population-based simulator

Development of a systematic approach to identify metabolites for herbal homologs based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry: gender-related difference in metabolism of Schisandra lignans in rats

Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state

In vivo metabolism study of rhubarb decoction in rat using high-performance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples

Losartan increases bradykinin levels in hypertensive humans

Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6

Metabolism and excretion of asenapine in healthy male subjects

Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats

In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry

Screening for in vitro metabolites of Abelmoschus manihot extract in intestinal bacteria by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity

CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population

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