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Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition

Clinical cancer research, 2011-04, Vol.17 (8), p.2216-2226

2011

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Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells

The Journal of biological chemistry, 2010-02, Vol.285 (9), p.6091-6100

2010

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Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26): Synthesis and Biological Evaluation of Imidazole Methyl 3-(4-(aryl-2-ylamino)phenyl)propanoates

Journal of medicinal chemistry, 2011-04, Vol.54 (8), p.2778-2791

2011

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Increasing Melanoma Cell Death Using Inhibitors of Protein Disulfide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (13), p.5363-5369

2008

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Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation

Journal of gastroenterology, 2021-11, Vol.56 (11), p.999-1007

2021

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Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: Potent CYP26 inhibitors and enhancers of all- trans retinoic acid activity in neuroblastoma cells

Bioorganic & medicinal chemistry, 2008-09, Vol.16 (17), p.8301-8313

2008

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Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates

Bioorganic & medicinal chemistry, 2012-10, Vol.20 (20), p.6080-6088

2012

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Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma

Experimental dermatology, 2013-11, Vol.22 (11), p.767-769

2013

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Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re‐sensitization by JNK inhibition

British journal of haematology, 2015-11, Vol.171 (4), p.595-605

2015

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Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death

Journal of investigative dermatology, 2015-06, Vol.135 (6), p.1629-1637

2015

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COX2 expression in neuroblastoma increases tumorigenicity but does not affect cell death in response to the COX2 inhibitor celecoxib

Clinical & experimental metastasis, 2014-08, Vol.31 (6), p.651-659

2014

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Combining the Endoplasmic Reticulum Stress–Inducing Agents Bortezomib and Fenretinide as a Novel Therapeutic Strategy for Metastatic Melanoma

Clinical cancer research, 2009-02, Vol.15 (4), p.1192-1198

2009

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Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold

Bioorganic & medicinal chemistry, 2012-07, Vol.20 (14), p.4201-4207

2012

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Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy

Journal of investigative dermatology, 2010-09, Vol.130 (9), p.2250-2258

2010

Volltextzugriff (PDF)

Synthesis and Biological Evaluation of 3-(1H-Imidazol- and Triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl Derivatives as Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26)

Journal of medicinal chemistry, 2011-10, Vol.54 (19), p.6803-6811

2011

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Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation

Organic & biomolecular chemistry, 2008-10, Vol.6 (19), p.3497-3507

2008

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Low Prevalence of the N363S Polymorphism of the Glucocorticoid Receptor in South Asians Living in the United Kingdom

The journal of clinical endocrinology and metabolism, 2004-01, Vol.89 (1), p.232-235

2004

Volltextzugriff (PDF)

Metabolites of endophytic fungi from Australian native plants as potential anticancer agents

FEMS microbiology letters, 2018-05, Vol.365 (9)

2018

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A common intron 2 polymorphism of the glucocorticoid receptor gene is associated with insulin resistance in men

Clinical endocrinology (Oxford), 2008-06, Vol.68 (6), p.879-884

2008

Volltextzugriff (PDF)

Azathioprine with Allopurinol: Lower Deoxythioguanosine in DNA and Transcriptome Changes Indicate Mechanistic Differences to Azathioprine Alone

Inflammatory bowel diseases, 2017-06, Vol.23 (6), p.946-955

2017

Volltextzugriff (PDF)

Liquid chromatography–mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-08, Vol.1028, p.175-180

2016

Volltextzugriff (PDF)

The Effect of Thiopurine Methyltransferase Expression on Sensitivity to Thiopurine Drugs

Molecular pharmacology, 2002-07, Vol.62 (1), p.102-109

2002

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Skeletal muscle mRNA levels for cathepsin B, but not components of the ubiquitin-proteasome pathway, are increased in patients with lung cancer referred for thoracotomy

Clinical science (1979), 2002-03, Vol.102 (3), p.353

2002

Volltextzugriff (PDF)

Store-operated Ca2+ entry in proliferating and retinoic acid-differentiated N- and S-type neuroblastoma cells

Biochimica et biophysica acta. Molecular cell research, 2013-03, Vol.1833 (3), p.643-651

2013

Volltextzugriff (PDF)

Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers

Molecular cancer therapeutics, 2011-03, Vol.10 (3), p.495-504

2011

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Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition

Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells

Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26): Synthesis and Biological Evaluation of Imidazole Methyl 3-(4-(aryl-2-ylamino)phenyl)propanoates

Increasing Melanoma Cell Death Using Inhibitors of Protein Disulfide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress

Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation

Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: Potent CYP26 inhibitors and enhancers of all- trans retinoic acid activity in neuroblastoma cells

Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates

Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma

Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re‐sensitization by JNK inhibition

Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death

COX2 expression in neuroblastoma increases tumorigenicity but does not affect cell death in response to the COX2 inhibitor celecoxib

Combining the Endoplasmic Reticulum Stress–Inducing Agents Bortezomib and Fenretinide as a Novel Therapeutic Strategy for Metastatic Melanoma

Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold

Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy

Synthesis and Biological Evaluation of 3-(1H-Imidazol- and Triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl Derivatives as Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26)

Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation

Low Prevalence of the N363S Polymorphism of the Glucocorticoid Receptor in South Asians Living in the United Kingdom

Metabolites of endophytic fungi from Australian native plants as potential anticancer agents

A common intron 2 polymorphism of the glucocorticoid receptor gene is associated with insulin resistance in men

Azathioprine with Allopurinol: Lower Deoxythioguanosine in DNA and Transcriptome Changes Indicate Mechanistic Differences to Azathioprine Alone

Liquid chromatography–mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients

The Effect of Thiopurine Methyltransferase Expression on Sensitivity to Thiopurine Drugs

Skeletal muscle mRNA levels for cathepsin B, but not components of the ubiquitin-proteasome pathway, are increased in patients with lung cancer referred for thoracotomy

Store-operated Ca2+ entry in proliferating and retinoic acid-differentiated N- and S-type neuroblastoma cells

Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers

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