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Does Huntingtin play a role in selective macroautophagy?

Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (17), p.3401-3413

Steffan, Joan S.

2010

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Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

The Journal of neuroscience, 2008-11, Vol.28 (45), p.11500-11510

2008

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Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

Human molecular genetics, 2008-12, Vol.17 (23), p.3767-3775

2008

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Transglutaminase 6 Is Colocalized and Interacts with Mutant Huntingtin in Huntington Disease Rodent Animal Models

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8914

2021

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A cause for childhood ataxia

eLife, 2016-03, Vol.5

Steffan, Joan S

2016

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Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice

Stem cell reports, 2018-01, Vol.10 (1), p.58-72

2018

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Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila

Experimental neurology, 2021-04, Vol.338, p.113463, Article 113463

2021

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Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

Journal of cell science, 2022-01, Vol.135 (2)

2022

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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

The Journal of cell biology, 2009-12, Vol.187 (7), p.1083-1099

2009

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Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Journal of Huntington's disease, 2022-01, Vol.11 (1), p.25-33

2022

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Autophagy researchers

Autophagy, 2014-02, Vol.10 (2), p.188-191

2014

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Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Stem cells translational medicine, 2017-06, Vol.6 (6), p.1477-1490

2017

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Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

Journal of Huntington's disease, 2018-01, Vol.7 (2), p.137-150

2018

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Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice

Journal of Huntington's disease, 2018-01, Vol.7 (4), p.321-335

2018

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RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I

The Journal of biological chemistry, 1996-08, Vol.271 (35), p.21062-21067

1996

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Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Biochemistry (Easton), 1988-11, Vol.27 (22), p.8393-8400

1988

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Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Molecular and Cellular Biology, 1998-07, Vol.18 (7), p.3752-3761

1998

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Expression and Function of a Mislocalized Form of Peroxisomal Malate Dehydrogenase (MDH3) in Yeast (∗)

The Journal of biological chemistry, 1995-09, Vol.270 (36), p.21220-21225

1995

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The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor

Genes & development, 1996-10, Vol.10 (20), p.2551-2563

1996

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Isolation and characterization of the yeast gene encoding the MDH3 isozyme of malate dehydrogenase

The Journal of biological chemistry, 1992-12, Vol.267 (34), p.24708-24715

1992

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RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae

Genes & development, 1994-10, Vol.8 (19), p.2349-2362

1994

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Expression and function of heterologous forms of malate dehydrogenase in yeast

Archives of biochemistry and biophysics, 1992-02, Vol.293 (1), p.93-102

1992

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Habitat fragmentation causes immediate and time-delayed biodiversity loss at different trophic levels

Ecology letters, 2010-05, Vol.13 (5), p.597-605

2010

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Extinction debt: a challenge for biodiversity conservation

Trends in ecology & evolution (Amsterdam), 2009-10, Vol.24 (10), p.564-571

2009

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Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment

Genomics (San Diego, Calif.), 2013-09, Vol.102 (3), p.157-162

2013

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Does Huntingtin play a role in selective macroautophagy?

Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

Transglutaminase 6 Is Colocalized and Interacts with Mutant Huntingtin in Huntington Disease Rodent Animal Models

A cause for childhood ataxia

Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice

Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila

Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Autophagy researchers

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice

RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I

Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Expression and Function of a Mislocalized Form of Peroxisomal Malate Dehydrogenase (MDH3) in Yeast (∗)

The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor

Isolation and characterization of the yeast gene encoding the MDH3 isozyme of malate dehydrogenase

RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae

Expression and function of heterologous forms of malate dehydrogenase in yeast

Habitat fragmentation causes immediate and time-delayed biodiversity loss at different trophic levels

Extinction debt: a challenge for biodiversity conservation

Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment

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