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Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

Drug resistance updates, 2012-08, Vol.15 (4), p.183-210

2012

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Targeted Nanomedicine for Cancer Therapeutics: Towards Precision Medicine Overcoming Drug Resistance

Drug resistance updates, 2017-03, Vol.31, p.15-30

2017

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The key roles of the lysine acetyltransferases KAT6A and KAT6B in physiology and pathology

Drug resistance updates, 2020-12, Vol.53, p.100729, Article 100729

2020

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Towards the overcoming of anticancer drug resistance mediated by p53 mutations

Drug resistance updates, 2020-03, Vol.49, p.100671-100671, Article 100671

2020

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The folate receptor as a rational therapeutic target for personalized cancer treatment

Drug resistance updates, 2014-10, Vol.17 (4), p.89-95

2014

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The multi-factorial nature of clinical multidrug resistance in cancer

Drug resistance updates, 2019-09, Vol.46, p.100645-100645, Article 100645

2019

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The role of alternative splicing in cancer: From oncogenesis to drug resistance

Drug resistance updates, 2020-12, Vol.53, p.100728-100728, Article 100728

2020

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ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion

PLoS computational biology, 2019-03, Vol.15 (3), p.e1006882-e1006882

2019

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Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach

Drug resistance updates, 2015-11, Vol.23, p.69-78

2015

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Genetic and Physiological Factors Affecting Human Milk Production and Composition

Nutrients, 2020-05, Vol.12 (5), p.1500

2020

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MicroRNAs as a drug resistance mechanism to targeted therapies in EGFR-mutated NSCLC: Current implications and future directions

Drug resistance updates, 2019-01, Vol.42, p.1-11

2019

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Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity

Cell death & disease, 2018-12, Vol.9 (12), p.1191-15, Article 1191

2018

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Mechanisms of cisplatin resistance and targeting of cancer stem cells: Adding glycosylation to the equation

Drug resistance updates, 2016-01, Vol.24 (C), p.34-54

2016

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Targeting metabolism to overcome cancer drug resistance: A promising therapeutic strategy for diffuse large B cell lymphoma

Drug resistance updates, 2022-03, Vol.61, p.100822-100822, Article 100822

2022

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Demonstrating aspects of multiscale modeling by studying the permeation pathway of the human ZnT2 zinc transporter

PLoS computational biology, 2018-11, Vol.14 (11), p.e1006503

2018

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Molecular basis of resistance to proteasome inhibitors in hematological malignancies

Drug resistance updates, 2015-01, Vol.18, p.18-35

2015

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Folylpolyglutamate synthetase mRNA G-quadruplexes regulate its cell protrusion localization and enhance a cancer cell invasive phenotype upon folate repletion

BMC biology, 2023-02, Vol.21 (1), p.13-13, Article 13

2023

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Albumin and Hyaluronic Acid-Coated Superparamagnetic Iron Oxide Nanoparticles Loaded with Paclitaxel for Biomedical Applications

Molecules (Basel, Switzerland), 2017-06, Vol.22 (7), p.1030

2017

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Targeted Nanoparticles Harboring Jasmine-Oil-Entrapped Paclitaxel for Elimination of Lung Cancer Cells

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1019

2021

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Deciphering molecular mechanisms underlying chemoresistance in relapsed AML patients: towards precision medicine overcoming drug resistance

Cancer cell international, 2021-01, Vol.21 (1), p.53-53, Article 53

2021

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Beta-casein nanovehicles for oral delivery of chemotherapeutic drugs

Nanomedicine, 2010-02, Vol.6 (1), p.119-126

2010

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Beta-casein Nanoparticles as an Oral Delivery System for Chemotherapeutic Drugs: Impact of Drug Structure and Properties on Co-assembly

Pharmaceutical research, 2010-10, Vol.27 (10), p.2175-2186

2010

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A transcriptomic examination of encased rotifer embryos reveals the developmental trajectory leading to long-term dormancy; are they "animal seeds"?

BMC genomics, 2024-01, Vol.25 (1), p.119-27, Article 119

2024

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The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity

Frontiers in pharmacology, 2024-08, Vol.15, p.1450418

2024

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Taxanes in cancer treatment: Activity, chemoresistance and its overcoming

Drug resistance updates, 2021-01, Vol.54, p.100742, Article 100742

2021

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Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

Targeted Nanomedicine for Cancer Therapeutics: Towards Precision Medicine Overcoming Drug Resistance

The key roles of the lysine acetyltransferases KAT6A and KAT6B in physiology and pathology

Towards the overcoming of anticancer drug resistance mediated by p53 mutations

The folate receptor as a rational therapeutic target for personalized cancer treatment

The multi-factorial nature of clinical multidrug resistance in cancer

The role of alternative splicing in cancer: From oncogenesis to drug resistance

ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion

Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach

Genetic and Physiological Factors Affecting Human Milk Production and Composition

MicroRNAs as a drug resistance mechanism to targeted therapies in EGFR-mutated NSCLC: Current implications and future directions

Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity

Mechanisms of cisplatin resistance and targeting of cancer stem cells: Adding glycosylation to the equation

Targeting metabolism to overcome cancer drug resistance: A promising therapeutic strategy for diffuse large B cell lymphoma

Demonstrating aspects of multiscale modeling by studying the permeation pathway of the human ZnT2 zinc transporter

Molecular basis of resistance to proteasome inhibitors in hematological malignancies

Folylpolyglutamate synthetase mRNA G-quadruplexes regulate its cell protrusion localization and enhance a cancer cell invasive phenotype upon folate repletion

Albumin and Hyaluronic Acid-Coated Superparamagnetic Iron Oxide Nanoparticles Loaded with Paclitaxel for Biomedical Applications

Targeted Nanoparticles Harboring Jasmine-Oil-Entrapped Paclitaxel for Elimination of Lung Cancer Cells

Deciphering molecular mechanisms underlying chemoresistance in relapsed AML patients: towards precision medicine overcoming drug resistance

Beta-casein nanovehicles for oral delivery of chemotherapeutic drugs

Beta-casein Nanoparticles as an Oral Delivery System for Chemotherapeutic Drugs: Impact of Drug Structure and Properties on Co-assembly

A transcriptomic examination of encased rotifer embryos reveals the developmental trajectory leading to long-term dormancy; are they "animal seeds"?

The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity

Taxanes in cancer treatment: Activity, chemoresistance and its overcoming

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