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Creating and screening natural product libraries

Natural product reports, 2020-07, Vol.37 (7), p.893-918

2020

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Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

Nature communications, 2018-09, Vol.9 (1), p.3881-9, Article 3881

2018

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Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus

PloS one, 2013-05, Vol.8 (5), p.e64449

2013

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Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

Antimicrobial agents and chemotherapy, 2015-12, Vol.59 (12), p.7290-7298

2015

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Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

Journal of Virology, 2010-03, Vol.84 (5), p.2511-2521

2010

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Activity of and Effect of Subcutaneous Treatment with the Broad-Spectrum Antiviral Lectin Griffithsin in Two Laboratory Rodent Models

Antimicrobial Agents and Chemotherapy, 2014-01, Vol.58 (1), p.120-127

2014

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Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (15), p.6099-6104

2009

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KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma

Nature communications, 2024-02, Vol.15 (1), p.1703-19, Article 1703

2024

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Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate

PloS one, 2011-08, Vol.6 (8), p.e22635

2011

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Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products

Molecular oncology, 2021-02, Vol.15 (2), p.381-406

2021

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Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.

The Journal of biological chemistry, 2005-03, Vol.280 (10), p.9345-9353

2005

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Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2

Proceedings of the National Academy of Sciences - PNAS, 2023-03, Vol.120 (10), p.e2214561120

2023

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NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp

Magnetic resonance in chemistry, 2021-05, Vol.59 (5), p.534-539

2021

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Antiviral lectins: Selective inhibitors of viral entry

Antiviral research, 2017-06, Vol.142, p.37-54

2017

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Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

Structure (London), 2010-09, Vol.18 (9), p.1104-1115

2010

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The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4+ cells

Virology (New York, N.Y.), 2012-02, Vol.423 (2), p.175-186

2012

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Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture

Frontiers in cellular and infection microbiology, 2020-11, Vol.10, p.561502-561502

2020

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Engineering soya bean seeds as a scalable platform to produce cyanovirin‐N, a non‐ARV microbicide against HIV

Plant biotechnology journal, 2015-09, Vol.13 (7), p.884-892

2015

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Binding of the Mannose-Specific Lectin, Griffithsin, to HIV-1 gp120 Exposes the CD4-Binding Site

Journal of Virology, 2011-09, Vol.85 (17), p.9039-9050

2011

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Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding

Structure (London), 2006-07, Vol.14 (7), p.1127-1135

2006

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Potent Anti-Influenza Activity of Cyanovirin-N and Interactions with Viral Hemagglutinin

Antimicrobial Agents and Chemotherapy, 2003-08, Vol.47 (8), p.2518-2525

2003

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Suggestive Evidence for Darwinian Selection against Asparagine-Linked Glycans of Plasmodium falciparum and Toxoplasma gondii

Eukaryotic Cell, 2010-02, Vol.9 (2), p.228-241

2010

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Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus

Antiviral research, 2003-03, Vol.58 (1), p.47-56

2003

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Structure of a lectin from the sea mussel Crenomytilus grayanus (CGL)

Acta crystallographica. Section F, Structural biology communications, 2015-11, Vol.71 (11), p.1429-1436

2015

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Creating and screening natural product libraries

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus

Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

Activity of and Effect of Subcutaneous Treatment with the Broad-Spectrum Antiviral Lectin Griffithsin in Two Laboratory Rodent Models

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma

Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate

Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products

Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.

Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2

NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp

Antiviral lectins: Selective inhibitors of viral entry

Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4+ cells

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture

Engineering soya bean seeds as a scalable platform to produce cyanovirin‐N, a non‐ARV microbicide against HIV

Binding of the Mannose-Specific Lectin, Griffithsin, to HIV-1 gp120 Exposes the CD4-Binding Site

Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding

Potent Anti-Influenza Activity of Cyanovirin-N and Interactions with Viral Hemagglutinin

Suggestive Evidence for Darwinian Selection against Asparagine-Linked Glycans of Plasmodium falciparum and Toxoplasma gondii

Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus

Structure of a lectin from the sea mussel Crenomytilus grayanus (CGL)

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