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Synthesis of Well-Defined Adenosine Diphosphate Ribose Oligomers

Angewandte Chemie International Edition, 2015-04, Vol.54 (16), p.4915-4918

International ed. in English, 2015

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Simplified Monopalmitoyl Toll‐like Receptor 2 Ligand Mini‐UPam for Self‐Adjuvanting Neoantigen‐Based Synthetic Cancer Vaccines

Chembiochem : a European journal of chemical biology, 2021-04, Vol.22 (7), p.1215-1222

2021

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Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen

Frontiers in chemistry, 2019-10, Vol.7, p.650-650

2019

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Efficient Induction of Antitumor Immunity by Synthetic Toll-like Receptor Ligand-Peptide Conjugates

Cancer immunology research, 2014-08, Vol.2 (8), p.756-764

2014

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Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions

Journal for immunotherapy of cancer, 2022-10, Vol.10 (10), p.e005016

2022

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Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG

PloS one, 2010-05, Vol.5 (5), p.e10626-e10626

2010

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Molecular Tools for the Study of ADP‐Ribosylation: A Unified and Versatile Method to Synthesise Native Mono‐ADP‐Ribosylated Peptides

Chemistry : a European journal, 2021-07, Vol.27 (41), p.10621-10627

2021

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Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.11691-11706

2020

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Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (31), p.e2203167119

2022

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Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

Chemical communications (Cambridge, England), 2012-01, Vol.48 (65), p.8093-8095

2012

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Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

Chemical communications (Cambridge, England), 2007-01 (15), p.1556-1558

2007

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Chemical synthesis of linear ADP-ribose oligomers up to pentamer and their binding to the oncogenic helicase ALC1

Chemical science (Cambridge), 2021-09, Vol.12 (37), p.12468-12475

2021

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Amyloid-like Behavior of Site-Specifically Citrullinated Myelin Oligodendrocyte Protein (MOG) Peptide Fragments inside EBV-Infected B‑Cells Influences Their Cytotoxicity and Autoimmunogenicity

Biochemistry (Easton), 2019-02, Vol.58 (6), p.763-775

2019

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Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells

Bioconjugate chemistry, 2019-04, Vol.30 (4), p.1150-1161

2019

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C‑Mannosyl Lysine for Solid Phase Assembly of Mannosylated Peptide Conjugate Cancer Vaccines

ACS chemical biology, 2020-03, Vol.15 (3), p.728-739

2020

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Combined Phosphoramidite‐Phosphodiester Reagents for the Synthesis of Methylene Bisphosphonates

Angewandte Chemie International Edition, 2017-03, Vol.56 (11), p.2955-2959

International ed. in English, 2017

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Bioorthogonal Deprotection on the Dendritic Cell Surface for Chemical Control of Antigen Cross-Presentation

Angewandte Chemie International Edition, 2015-05, Vol.54 (19), p.5628-5631

International ed. in English, 2015

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Synthesis of C‐Glycosyl Amino Acid Building Blocks Suitable for the Solid‐Phase Synthesis of Multivalent Glycopeptide Mimics

European journal of organic chemistry, 2020-08, Vol.2020 (32), p.5126-5139

2020

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Multivalent, Stabilized Mannose‐6‐Phosphates for the Targeted Delivery of Toll‐Like Receptor Ligands and Peptide Antigens

Chembiochem : a European journal of chemical biology, 2021-01, Vol.22 (2), p.434-440

2021

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TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients

Oncotarget, 2016-10, Vol.7 (41), p.67087-67100

2016

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Interaction of the amyloid β peptide with sodium dodecyl sulfate as a membrane-mimicking detergent

Journal of biological physics, 2016-06, Vol.42 (3), p.299-315

2016

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On the Synthesis of Oligonucleotides Interconnected through Pyrophosphate Linkages

European journal of organic chemistry, 2015-09, Vol.2015 (27), p.6084-6091

2015

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Targeted Lysosome Disruptive Elements for Improvement of Parenchymal Liver Cell-specific Gene Delivery

The Journal of biological chemistry, 2002-11, Vol.277 (48), p.45803-45810

2002

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Chemical synthesis of picornaviral protein primers of RNA replication

Organic & biomolecular chemistry, 2006-01, Vol.4 (19), p.3576-3586

2006

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Design of a Ribosyltriazole-Annulated Cyclooctyne for Oligonucleotide Labeling by Strain-Promoted Alkyne-Azide Cycloaddition

European journal of organic chemistry, 2014-12, Vol.2014 (34), p.7566-7571

2014

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Synthesis of Well-Defined Adenosine Diphosphate Ribose Oligomers

Simplified Monopalmitoyl Toll‐like Receptor 2 Ligand Mini‐UPam for Self‐Adjuvanting Neoantigen‐Based Synthetic Cancer Vaccines

Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen

Efficient Induction of Antitumor Immunity by Synthetic Toll-like Receptor Ligand-Peptide Conjugates

Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions

Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG

Molecular Tools for the Study of ADP‐Ribosylation: A Unified and Versatile Method to Synthesise Native Mono‐ADP‐Ribosylated Peptides

Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides

Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo

Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

Chemical synthesis of linear ADP-ribose oligomers up to pentamer and their binding to the oncogenic helicase ALC1

Amyloid-like Behavior of Site-Specifically Citrullinated Myelin Oligodendrocyte Protein (MOG) Peptide Fragments inside EBV-Infected B‑Cells Influences Their Cytotoxicity and Autoimmunogenicity

Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells

C‑Mannosyl Lysine for Solid Phase Assembly of Mannosylated Peptide Conjugate Cancer Vaccines

Combined Phosphoramidite‐Phosphodiester Reagents for the Synthesis of Methylene Bisphosphonates

Bioorthogonal Deprotection on the Dendritic Cell Surface for Chemical Control of Antigen Cross-Presentation

Synthesis of C‐Glycosyl Amino Acid Building Blocks Suitable for the Solid‐Phase Synthesis of Multivalent Glycopeptide Mimics

Multivalent, Stabilized Mannose‐6‐Phosphates for the Targeted Delivery of Toll‐Like Receptor Ligands and Peptide Antigens

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients

Interaction of the amyloid β peptide with sodium dodecyl sulfate as a membrane-mimicking detergent

On the Synthesis of Oligonucleotides Interconnected through Pyrophosphate Linkages

Targeted Lysosome Disruptive Elements for Improvement of Parenchymal Liver Cell-specific Gene Delivery

Chemical synthesis of picornaviral protein primers of RNA replication

Design of a Ribosyltriazole-Annulated Cyclooctyne for Oligonucleotide Labeling by Strain-Promoted Alkyne-Azide Cycloaddition

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