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The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

Nucleic acids research, 2018-01, Vol.46 (2), p.661-676

2018

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Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5'-UTR of KRAS oncogene represses translation

Chemical communications (Cambridge, England), 2012-01, Vol.48 (6), p.874-876

2012

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Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins

Nucleic acids research, 2008-06, Vol.36 (11), p.3765-3780

2008

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Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA

Biochimica et biophysica acta. General subjects, 2017-05, Vol.1861 (5), p.1389-1398

2017

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Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription

Nucleic acids research, 2009-05, Vol.37 (9), p.2841-2853

2009

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Photosensitizers Binding to Nucleic Acids as Anticancer Agents

Future medicinal chemistry, 2016-02, Vol.8 (2), p.179-194

2016

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Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

Nucleic acids research, 2008-06, Vol.36 (10), p.3494-3507

2008

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G-rich Oligonucleotide Inhibits the Binding of a Nuclear Protein to the Ki-ras Promoter and Strongly Reduces Cell Growth in Human Carcinoma Pancreatic Cells

Biochemistry (Easton), 2004-03, Vol.43 (9), p.2512-2523

2004

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G4 DNA in ras genes and its potential in cancer therapy

Biochimica et biophysica acta, 2016-04, Vol.1859 (4), p.663-674

2016

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HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property

Nucleic acids research, 2014-07, Vol.42 (13), p.8379-8388

2014

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Antisense locked nucleic acids efficiently suppress BCR/ABL and induce cell growth decline and apoptosis in leukemic cells

Molecular cancer therapeutics, 2006-07, Vol.5 (7), p.1683-1692

2006

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Spectroscopic characterization of the oxidation control of the iso-pentaphyrin/pentaphyrin system

Tetrahedron, 2006-08, Vol.62 (34), p.8147-8151

2006

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Synthesis and Biological Evaluation of New Pentaphyrin Macrocycles for Photodynamic Therapy

Journal of medicinal chemistry, 2006-01, Vol.49 (1), p.196-204

2006

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Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRASG-quadruplexes

Chemical communications (Cambridge, England), 2010, Vol.46 (4), p.625-627

2010

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RNA G‑Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9448-9461

2017

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Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

Molecular cancer, 2014-04, Vol.13 (1), p.75-75, Article 75

2014

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MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

Nucleic acids research, 2013-04, Vol.41 (7), p.4049-4064

2013

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Photosensitizers binding to nucleic acids as anticancer agents

Future medicinal chemistry, 2016, Vol.8 (2), p.179-194

2016

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Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding

Cancer gene therapy, 2004-07, Vol.11 (7), p.465-476

2004

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Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells

Journal of medicinal chemistry, 2015-07, Vol.58 (14), p.5476-5485

2015

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Primer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: analysis of the human KRAS NHE

Chemical communications (Cambridge, England), 2011-05, Vol.47 (17), p.4965-4967

2011

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Guanidino Anthrathiophenediones as G‑Quadruplex Binders: Uptake, Intracellular Localization, and Anti-Harvey-ras Gene Activity in Bladder Cancer Cells

Journal of medicinal chemistry, 2013-04, Vol.56 (7), p.2764-2778

2013

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Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes

Chemical communications (Cambridge, England), 2010-01, Vol.46 (4), p.625-627

2010

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Enhanced G4-DNA binding of 5,10,15,20 (N-propyl-4-pyridyl) porphyrin (TPrPyP4): A comparative study with TMPyP4Electronic supplementary information (ESI) available: Experimental procedures, Scatchard plots, G4-DNA and porphyrin structures. See DOI: 10.1039/c0cc01912g

2010-10

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Enhanced G4-DNA binding of 5,10,15,20 (N-propyl-4-pyridyl) porphyrin (TPrPyP4): a comparative study with TMPyP4

Chemical communications (Cambridge, England), 2010-10, Vol.46 (39), p.7364-7366

2010

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The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5'-UTR of KRAS oncogene represses translation

Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins

Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA

Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription

Photosensitizers Binding to Nucleic Acids as Anticancer Agents

Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

G-rich Oligonucleotide Inhibits the Binding of a Nuclear Protein to the Ki-ras Promoter and Strongly Reduces Cell Growth in Human Carcinoma Pancreatic Cells

G4 DNA in ras genes and its potential in cancer therapy

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property

Antisense locked nucleic acids efficiently suppress BCR/ABL and induce cell growth decline and apoptosis in leukemic cells

Spectroscopic characterization of the oxidation control of the iso-pentaphyrin/pentaphyrin system

Synthesis and Biological Evaluation of New Pentaphyrin Macrocycles for Photodynamic Therapy

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRASG-quadruplexes

RNA G‑Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation

Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

Photosensitizers binding to nucleic acids as anticancer agents

Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding

Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells

Primer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: analysis of the human KRAS NHE

Guanidino Anthrathiophenediones as G‑Quadruplex Binders: Uptake, Intracellular Localization, and Anti-Harvey-ras Gene Activity in Bladder Cancer Cells

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes

Enhanced G4-DNA binding of 5,10,15,20 (N-propyl-4-pyridyl) porphyrin (TPrPyP4): A comparative study with TMPyP4Electronic supplementary information (ESI) available: Experimental procedures, Scatchard plots, G4-DNA and porphyrin structures. See DOI: 10.1039/c0cc01912g

Enhanced G4-DNA binding of 5,10,15,20 (N-propyl-4-pyridyl) porphyrin (TPrPyP4): a comparative study with TMPyP4

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