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Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

The Journal of biological chemistry, 2015-02, Vol.290 (8), p.4908-4927

2015

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Sar1 GTPase Activity Is Regulated by Membrane Curvature

The Journal of biological chemistry, 2016-01, Vol.291 (3), p.1014-1027

2016

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Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2

The Journal of biological chemistry, 2018-03, Vol.293 (10), p.3685-3699

2018

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Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42

The Journal of biological chemistry, 2020-04, Vol.295 (15), p.4822-4835

2020

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The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3134-3147

2020

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IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

The Journal of biological chemistry, 2016-12, Vol.291 (51), p.26364-26376

2016

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Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

The Journal of biological chemistry, 2019-11, Vol.294 (44), p.16198-16213

2019

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LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway

The Journal of biological chemistry, 2017-09, Vol.292 (36), p.14989-15001

2017

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Hepatocyte Growth Factor-induced Asef-IQGAP1 Complex Controls Cytoskeletal Remodeling and Endothelial Barrier

The Journal of biological chemistry, 2015-02, Vol.290 (7), p.4097-4109

2015

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Combined Rational Design and a High Throughput Screening Platform for Identifying Chemical Inhibitors of a Ras-activating Enzyme

The Journal of biological chemistry, 2015-05, Vol.290 (20), p.12879-12898

2015

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Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.18105-18121

2020

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IQGAP1 Binds to Estrogen Receptor-α and Modulates Its Function

The Journal of biological chemistry, 2014-03, Vol.289 (13), p.9100-9112

2014

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IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity

The Journal of biological chemistry, 2016-09, Vol.291 (37), p.19261-19273

2016

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The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2

The Journal of biological chemistry, 2017-05, Vol.292 (21), p.8750-8761

2017

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IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold

The Journal of biological chemistry, 2012-06, Vol.287 (27), p.22483-22496

2012

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Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1)

The Journal of biological chemistry, 2015-09, Vol.290 (39), p.23984-23996

2015

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Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer

The Journal of biological chemistry, 2020-01, Vol.295 (4), p.1105-1119

2020

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Rho Isoform-specific Interaction with IQGAP1 Promotes Breast Cancer Cell Proliferation and Migration

The Journal of biological chemistry, 2012-11, Vol.287 (45), p.38367-38378

2012

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Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration

The Journal of biological chemistry, 2015-09, Vol.290 (39), p.23766-23780

2015

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IQGAP1 Protein Regulates Nuclear Localization of β-Catenin via Importin-β5 Protein in Wnt Signaling

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36351-36360

2013

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Ca2+-dependent Monomer and Dimer Formation Switches CAPRI Protein between Ras GTPase-activating Protein (GAP) and RapGAP Activities

The Journal of biological chemistry, 2011-06, Vol.286 (22), p.19905-19916

2011

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S100P Is a Novel Interaction Partner and Regulator of IQGAP1

The Journal of biological chemistry, 2011-03, Vol.286 (9), p.7227-7238

2011

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A Novel Role for Gab1 and SHP2 in Epidermal Growth Factor-induced Ras Activation

The Journal of biological chemistry, 2005-02, Vol.280 (7), p.5350-5360

2005

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MAPK Scaffold IQGAP1 Binds the EGF Receptor and Modulates Its Activation

The Journal of biological chemistry, 2011-04, Vol.286 (17), p.15010-15021

2011

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Semaphorin 4D/Plexin-B1 Stimulates PTEN Activity through R-Ras GTPase-activating Protein Activity, Inducing Growth Cone Collapse in Hippocampal Neurons

The Journal of biological chemistry, 2010-09, Vol.285 (36), p.28200-28209

2010

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Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

Sar1 GTPase Activity Is Regulated by Membrane Curvature

Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2

Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42

The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES

Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway

Hepatocyte Growth Factor-induced Asef-IQGAP1 Complex Controls Cytoskeletal Remodeling and Endothelial Barrier

Combined Rational Design and a High Throughput Screening Platform for Identifying Chemical Inhibitors of a Ras-activating Enzyme

Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function

IQGAP1 Binds to Estrogen Receptor-α and Modulates Its Function

IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity

The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2

IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold

Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1)

Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer

Rho Isoform-specific Interaction with IQGAP1 Promotes Breast Cancer Cell Proliferation and Migration

Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration

IQGAP1 Protein Regulates Nuclear Localization of β-Catenin via Importin-β5 Protein in Wnt Signaling

Ca2+-dependent Monomer and Dimer Formation Switches CAPRI Protein between Ras GTPase-activating Protein (GAP) and RapGAP Activities

S100P Is a Novel Interaction Partner and Regulator of IQGAP1

A Novel Role for Gab1 and SHP2 in Epidermal Growth Factor-induced Ras Activation

MAPK Scaffold IQGAP1 Binds the EGF Receptor and Modulates Its Activation

Semaphorin 4D/Plexin-B1 Stimulates PTEN Activity through R-Ras GTPase-activating Protein Activity, Inducing Growth Cone Collapse in Hippocampal Neurons

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