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Targeting the sarcomere to correct muscle function

Nature reviews. Drug discovery, 2015-05, Vol.14 (5), p.313-328

2015

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Targeted expression, purification, and cleavage of fusion proteins from inclusion bodies in Escherichia coli

FEBS letters, 2014-01, Vol.588 (2), p.247-252

2014

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Structural and functional analysis of the Na+/H+ exchanger

Biochemical journal, 2007-02, Vol.401 (3), p.623-633

2007

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Metabolomic profiling of asthma: Diagnostic utility of urine nuclear magnetic resonance spectroscopy

Journal of allergy and clinical immunology, 2011-03, Vol.127 (3), p.757-764.e6

2011

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Investigations of the Effects of Gender, Diurnal Variation, and Age in Human Urinary Metabolomic Profiles

Analytical chemistry (Washington), 2007-09, Vol.79 (18), p.6995-7004

2007

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Urine stability for metabolomic studies: effects of preparation and storage

Metabolomics, 2007-03, Vol.3 (1), p.19-27

2007

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Rewiring AMPK and Mitochondrial Retrograde Signaling for Metabolic Control of Aging and Histone Acetylation in Respiratory-Defective Cells

Cell reports (Cambridge), 2014-04, Vol.7 (2), p.565-574

2014

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Solution Structure of Human Cardiac Troponin C in Complex with the Green Tea Polyphenol, (−)-Epigallocatechin 3-Gallate

The Journal of biological chemistry, 2009-08, Vol.284 (34), p.23012-23023

2009

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A Common Phenotype Polymorphism in Mammalian Brains Defined by Concomitant Production of Prolactin and Growth Hormone

PloS one, 2016-02, Vol.11 (2), p.e0149410-e0149410

2016

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Ubiquinone-binding Site Mutations in the Saccharomyces cerevisiae Succinate Dehydrogenase Generate Superoxide and Lead to the Accumulation of Succinate

The Journal of biological chemistry, 2007-09, Vol.282 (37), p.27518-27526

2007

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A PagP fusion protein system for the expression of intrinsically disordered proteins in Escherichia coli

Protein expression and purification, 2012-09, Vol.85 (1), p.148-151

2012

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Fluorine labelling for in situ 19F NMR in oriented systems

Journal of biomolecular NMR, 2024-02

2024

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Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3026-3034

2021

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Structural and Functional Characterization of Transmembrane Segment VII of the Na+/H+ Exchanger Isoform 1

The Journal of biological chemistry, 2006-10, Vol.281 (40), p.29817-29829

2006

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Structural and Functional Analysis of Transmembrane XI of the NHE1 Isoform of the Na+/H+ Exchanger

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11546-11556

2009

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Drugging the Sarcomere, a Delicate Balance: Position of N‑Terminal Charge of the Inhibitor W7

ACS chemical biology, 2022-06, Vol.17 (6), p.1495-1504

2022

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[12] Chemical shifts as a tool for structure determination

Methods in Enzymology, 1994, Vol.239, p.363-392

1994

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Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir

Journal of the American Chemical Society, 2011-02, Vol.133 (7), p.2264-2274

2011

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Relative and Regional Stabilities of the Hamster, Mouse, Rabbit, and Bovine Prion Proteins toward Urea Unfolding Assessed by Nuclear Magnetic Resonance and Circular Dichroism Spectroscopies

Biochemistry (Easton), 2011-09, Vol.50 (35), p.7536-7545

2011

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Feasibility of trifluoromethyl TROSY NMR at high magnetic fields

Journal of biomolecular NMR, 2019-11, Vol.73 (10-11), p.519-523

2019

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Structural and Functional Characterization of Transmembrane Segment IV of the NHE1 Isoform of the Na+/H+ Exchanger

The Journal of biological chemistry, 2005-05, Vol.280 (18), p.17863-17872

2005

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HMDB: the Human Metabolome Database

Nucleic acids research, 2007-01, Vol.35 (Database issue), p.D521

2007

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The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C

Biochemistry and biophysics reports, 2018-12, Vol.16, p.145-151

2018

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Conversion of a Cardiac Muscle Modulator from an Inhibitor to an Activator

ACS medicinal chemistry letters, 2023-04, Vol.14 (4), p.530-533

2023

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Targeting the sarcomere to correct muscle function

Targeted expression, purification, and cleavage of fusion proteins from inclusion bodies in Escherichia coli

Structural and functional analysis of the Na+/H+ exchanger

Metabolomic profiling of asthma: Diagnostic utility of urine nuclear magnetic resonance spectroscopy

Investigations of the Effects of Gender, Diurnal Variation, and Age in Human Urinary Metabolomic Profiles

Urine stability for metabolomic studies: effects of preparation and storage

Rewiring AMPK and Mitochondrial Retrograde Signaling for Metabolic Control of Aging and Histone Acetylation in Respiratory-Defective Cells

Solution Structure of Human Cardiac Troponin C in Complex with the Green Tea Polyphenol, (−)-Epigallocatechin 3-Gallate

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles

A Common Phenotype Polymorphism in Mammalian Brains Defined by Concomitant Production of Prolactin and Growth Hormone

Ubiquinone-binding Site Mutations in the Saccharomyces cerevisiae Succinate Dehydrogenase Generate Superoxide and Lead to the Accumulation of Succinate

A PagP fusion protein system for the expression of intrinsically disordered proteins in Escherichia coli

Fluorine labelling for in situ 19F NMR in oriented systems

Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle

Structural and Functional Characterization of Transmembrane Segment VII of the Na+/H+ Exchanger Isoform 1

Structural and Functional Analysis of Transmembrane XI of the NHE1 Isoform of the Na+/H+ Exchanger

Drugging the Sarcomere, a Delicate Balance: Position of N‑Terminal Charge of the Inhibitor W7

[12] Chemical shifts as a tool for structure determination

Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir

Relative and Regional Stabilities of the Hamster, Mouse, Rabbit, and Bovine Prion Proteins toward Urea Unfolding Assessed by Nuclear Magnetic Resonance and Circular Dichroism Spectroscopies

Feasibility of trifluoromethyl TROSY NMR at high magnetic fields

Structural and Functional Characterization of Transmembrane Segment IV of the NHE1 Isoform of the Na+/H+ Exchanger

HMDB: the Human Metabolome Database

The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C

Conversion of a Cardiac Muscle Modulator from an Inhibitor to an Activator

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