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Predicting the impact of physiological and biochemical processes on oral drug bioavailability

Advanced drug delivery reviews, 2001-10, Vol.50, p.S41-S67

2001

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In silico modeling of non-linear drug absorption for the P-gp substrate talinolol and of consequences for the resulting pharmacodynamic effect

Pharmaceutical research, 2006-08, Vol.23 (8), p.1712-1720

2006

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Predicting the Effect of Fed-State Intestinal Contents on Drug Dissolution

Pharmaceutical research, 2010-12, Vol.27 (12), p.2646-2656

2010

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Mutagenesis and Cysteine Scanning of Transmembrane Domain 10 of the Human Dipeptide Transporter

Pharmaceutical research, 2009-10, Vol.26 (10), p.2358-2366

2009

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Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore

Bioorganic & medicinal chemistry, 2007-07, Vol.15 (14), p.4985-5002

2007

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Applications of supercritical fluids to enhance the dissolution behaviors of Furosemide by generation of microparticles and solid dispersions

European journal of pharmaceutics and biopharmaceutics, 2012-05, Vol.81 (1), p.131-141

2012

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Structure, Function, and Molecular Modeling Approaches to the Study of the Intestinal Dipeptide Transporter PepT1

Journal of pharmaceutical sciences, 1998-11, Vol.87 (11), p.1286-1291

1998

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Biopharmaceutics of transmucosal peptide and protein drug administration: role of transport mechanisms with a focus on the involvement of PepT1

Journal of controlled release, 1999-11, Vol.62 (1-2), p.129-140

1999

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In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol

Psychopharmacologia, 1999-02, Vol.141 (4), p.339-350

1999

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Synthesis and in Vitro Activity of 3β-Substituted-3α-hydroxypregnan-20-ones: Allosteric Modulators of the GABAA Receptor

Journal of medicinal chemistry, 1997-01, Vol.40 (1), p.61-72

1997

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Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one

European journal of pharmacology, 1989-07, Vol.166 (2), p.325-329

1989

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Proton-driven dipeptide uptake in primary cultured rabbit conjunctival epithelial cells

Investigative ophthalmology & visual science, 1998-11, Vol.39 (12), p.2365-2373

1998

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Differential Responses of Expressed Recombinant Human γ‐Aminobutyric AcidA Receptors to Neurosteroids

Journal of neurochemistry, 1991-11, Vol.57 (5), p.1818-1821

1991

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Pressure-sensitive and -insensitive coupling in γ-aminobutyric acida receptors

Psychopharmacologia, 2001-10, Vol.157 (4), p.401-410

2001

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In vitro and in vivo activity of 16,17-dehydro-epipregnanolones : 17,20-bond torsional energy analysis and D-ring conformation

Pharmaceutical research, 1996-10, Vol.13 (10), p.1488-1494

1996

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Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an expressed GABAA receptor

Neurochemical research, 1991-03, Vol.16 (3), p.347-356

1991

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[2] Computer modeling of combining site structure of anti-hapten monoclonal antibodies

Methods in Enzymology, 1991, Vol.203, p.21-45

1991

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The neuroactive steroid 3α-hydroxy-5β-pregnan-20-one is a two-component modulator of ligand binding to the GABAA receptor

European journal of pharmacology. Molecular pharmacology section, 1994-10, Vol.269 (2), p.157-163

1994

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Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?: A Scientific Statement From the American Heart Association

Circulation, 2012-05, Vol.125 (20), p.2520-2544

2012

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Update on Cardiovascular Implantable Electronic Device Infections and Their Management: A Scientific Statement From the American Heart Association

Circulation (New York, N.Y.), 2010-01, Vol.121 (3), p.458-477

2010

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Third universal definition of myocardial infarction

European heart journal, 2012-10, Vol.33 (20), p.2551-2567

2012

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Accuracy of CT in the diagnosis of pulmonary embolism: a systematic literature review

American journal of roentgenology (1976), 2004-12, Vol.183 (6), p.1819-1827

2004

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Usefulness of clinical prediction rules for the diagnosis of venous thromboembolism: A systematic review

The American journal of medicine, 2004-11, Vol.117 (9), p.676-684

2004

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Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose–response framework

Toxicology and applied pharmacology, 2007-07, Vol.222 (1), p.122-128

2007

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A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens

Critical reviews in toxicology, 2011-07, Vol.41 (6), p.507-544

2011

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Predicting the impact of physiological and biochemical processes on oral drug bioavailability

In silico modeling of non-linear drug absorption for the P-gp substrate talinolol and of consequences for the resulting pharmacodynamic effect

Predicting the Effect of Fed-State Intestinal Contents on Drug Dissolution

Mutagenesis and Cysteine Scanning of Transmembrane Domain 10 of the Human Dipeptide Transporter

Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore

Applications of supercritical fluids to enhance the dissolution behaviors of Furosemide by generation of microparticles and solid dispersions

Structure, Function, and Molecular Modeling Approaches to the Study of the Intestinal Dipeptide Transporter PepT1

Biopharmaceutics of transmucosal peptide and protein drug administration: role of transport mechanisms with a focus on the involvement of PepT1

In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol

Synthesis and in Vitro Activity of 3β-Substituted-3α-hydroxypregnan-20-ones: Allosteric Modulators of the GABAA Receptor

Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one

Proton-driven dipeptide uptake in primary cultured rabbit conjunctival epithelial cells

Differential Responses of Expressed Recombinant Human γ‐Aminobutyric AcidA Receptors to Neurosteroids

Pressure-sensitive and -insensitive coupling in γ-aminobutyric acida receptors

In vitro and in vivo activity of 16,17-dehydro-epipregnanolones : 17,20-bond torsional energy analysis and D-ring conformation

Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an expressed GABAA receptor

[2] Computer modeling of combining site structure of anti-hapten monoclonal antibodies

The neuroactive steroid 3α-hydroxy-5β-pregnan-20-one is a two-component modulator of ligand binding to the GABAA receptor

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?: A Scientific Statement From the American Heart Association

Update on Cardiovascular Implantable Electronic Device Infections and Their Management: A Scientific Statement From the American Heart Association

Third universal definition of myocardial infarction

Accuracy of CT in the diagnosis of pulmonary embolism: a systematic literature review

Usefulness of clinical prediction rules for the diagnosis of venous thromboembolism: A systematic review

Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose–response framework

A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens

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