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Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Immunity (Cambridge, Mass.), 2016-05, Vol.44 (5), p.1151-1161

2016

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Tyrosine phosphorylation in Toll-like receptor signaling

Cytokine & growth factor reviews, 2014-10, Vol.25 (5), p.533-541

2014

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dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

Journal of interferon & cytokine research, 2014-06, Vol.34 (6), p.427

2014

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Interferons and viral infections

BioFactors (Oxford), 2009-01, Vol.35 (1), p.14-20

2009

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Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Nature communications, 2020-02, Vol.11 (1), p.900-15, Article 900

2020

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RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Protein & Cell, 2017-03, Vol.8 (3), p.165-168

2017

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Interferons at age 50: past, current and future impact on biomedicine

Nature reviews. Drug discovery, 2007-12, Vol.6 (12), p.975-990

2007

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p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.E89-E98

2013

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Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

The EMBO journal, 2008-12, Vol.27 (24), p.3311-3321

2008

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A Role for Ifit2 in Restricting West Nile Virus Infection in the Brain

Journal of Virology, 2013-08, Vol.87 (15), p.8363-8371

2013

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Interferon-induced Ifit proteins: their role in viral pathogenesis

Journal of virology, 2015-03, Vol.89 (5), p.2462-2468

2015

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Viral apoptosis is induced by IRF-3-mediated activation of Bax

The EMBO journal, 2010-05, Vol.29 (10), p.1762-1773

2010

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Intracranial delivery of antisense locked nucleic acids for silencing microRNAs in the mouse brain

STAR protocols, 2022-12, Vol.3 (4), p.101836-101836, Article 101836

2022

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Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling

Science signaling, 2012-07, Vol.5 (233), p.ra50

2012

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A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

Virology (New York, N.Y.), 2007-06, Vol.363 (1), p.236-243

2007

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Viral degradasome hijacks mitochondria to suppress innate immunity

Cell research, 2013-08, Vol.23 (8), p.1025-1042

2013

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Crystal structure of IFIT2 (ISG54) predicts functional properties of IFITs

Cell research, 2012-10, Vol.22 (10), p.1407-1409

2012

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Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA

Virology (New York, N.Y.), 2006-05, Vol.349 (1), p.13-21

2006

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Innate Immune Responses to Herpesvirus Infection

Cells (Basel, Switzerland), 2021-08, Vol.10 (8), p.2122

2021

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Ifit2 Deficiency Results in Uncontrolled Neurotropic Coronavirus Replication and Enhanced Encephalitis via Impaired Alpha/Beta Interferon Induction in Macrophages

Journal of Virology, 2014-01, Vol.88 (2), p.1051-1064

2014

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Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Journal of virology, 2023-12, Vol.97 (12), p.e0130423-e0130423

2023

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Role of Interferon Regulatory Factor 3-Mediated Apoptosis in the Establishment and Maintenance of Persistent Infection by Sendai Virus

Journal of Virology, 2013-01, Vol.87 (1), p.16-24

2013

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The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Cell death and differentiation, 2022-03, Vol.29 (3), p.504-513

2022

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Meet the Terminator: The Phosphatase PP2A Puts Brakes on IRF-3 Activation

Molecular cell, 2014-04, Vol.54 (2), p.210-211

2014

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Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Tyrosine phosphorylation in Toll-like receptor signaling

dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

Interferons and viral infections

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Interferons at age 50: past, current and future impact on biomedicine

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

A Role for Ifit2 in Restricting West Nile Virus Infection in the Brain

Interferon-induced Ifit proteins: their role in viral pathogenesis

Viral apoptosis is induced by IRF-3-mediated activation of Bax

Intracranial delivery of antisense locked nucleic acids for silencing microRNAs in the mouse brain

Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling

A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

Viral degradasome hijacks mitochondria to suppress innate immunity

Crystal structure of IFIT2 (ISG54) predicts functional properties of IFITs

Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA

Innate Immune Responses to Herpesvirus Infection

Ifit2 Deficiency Results in Uncontrolled Neurotropic Coronavirus Replication and Enhanced Encephalitis via Impaired Alpha/Beta Interferon Induction in Macrophages

Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Role of Interferon Regulatory Factor 3-Mediated Apoptosis in the Establishment and Maintenance of Persistent Infection by Sendai Virus

The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Meet the Terminator: The Phosphatase PP2A Puts Brakes on IRF-3 Activation

PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation

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