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Die Stiftung Emilia Guggenheim-Schnurr der Naturforschenden Gesellschaft in Basel

Mitteilungen der Naturforschenden Gesellschaften beider Basel, 2017, Vol.17, p.103

Regenass, Urs

2017

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Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.9832-9843

2014

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Correction to “Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90”

Journal of medicinal chemistry, 2019-12, Vol.62 (23), p.10926-10926

2019

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Metastatic disease: A drug discovery perspective

Seminars in cancer biology, 2012-06, Vol.22 (3), p.261-271

2012

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Abstract 3779: Treatment of experimental brain metastasis of human breast cancer by macitentan, a dual antagonist of endothelin receptors combined with paclitaxel

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.3779-3779

2014

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Stable Amplification of the S-Adenosylmethionine Decarboxylase Gene in Chinese Hamster Ovary Cells (∗)

The Journal of biological chemistry, 1995-02, Vol.270 (5), p.2124-2132

1995

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Antitumor Compound Testing in Glioblastoma Organotypic Brain Cultures

Journal of biomolecular screening, 2011-09, Vol.16 (8), p.805-817

2011

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Abstract 5481: Therapy of human LN229 glioblastoma growing in the brain of nude mice by Macitentan, a dual endothelin receptor A and B antagonist, combined with Temozolomide

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.5481-5481

2013

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Antivascular Therapy for Multidrug-Resistant Ovarian Tumors by Macitentan, a Dual Endothelin Receptor Antagonist

Translational oncology, 2012-02, Vol.5 (1), p.39-47

2012

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Abstract 4274: Characterization and drug sensitivity testing of HTS compatible cancer microtissues

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4274-4274

2011

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Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.601-601

2011

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Macitentan (ACT-064992), a Tissue-Targeting Endothelin Receptor Antagonist, Enhances Therapeutic Efficacy of Paclitaxel by Modulating Survival Pathways in Orthotopic Models of Metastatic Human Ovarian Cancer12

Neoplasia (New York, N.Y.), 2011-02, Vol.13 (2), p.167-179

2011

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Antivascular Therapy for Multidrug-Resistant Ovarian Tumors by Macitentan, a Dual Endothelin Receptor Antagonist1

Translational oncology, 2012-02, Vol.5 (1), p.39-47

2012

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The protein kinase C inhibitor CGP 41251, a staurosporine derivative with antitumor activity, reverses multidrug resistance

International journal of cancer, 1994-04, Vol.57 (1), p.104-110

1994

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Reversal of multidrug resistance by the staurosporine derivatives CGP 41251 and CGP 42700

International journal of cancer, 1998-07, Vol.77 (1), p.64-69

1998

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Experimental induction of testicular teratomas in dissociated–reaggregated chimaeric gonads

Development (Cambridge), 1982-12, Vol.72 (1), p.153-167

1982

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Thiazolidine-diones. Biochemical and biological activity of a novel class of tyrosine protein kinase inhibitors

The Journal of biological chemistry, 1990-12, Vol.265 (36), p.22255-22261

1990

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S-Adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogs of methylglyoxal bis(guanylhydrazone)

Journal of medicinal chemistry, 1993, Vol.36 (1), p.46-54

1993

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4-Amidinoindan-1-one 2'-amidinohydrazone: a new potent and selective inhibitor of S-adenosylmethionine decarboxylase

Journal of medicinal chemistry, 1993-07, Vol.36 (15), p.2168-2171

1993

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2-Substituted 3-(aminooxy)propanamines as inhibitors of ornithine decarboxylase: synthesis and biological activity

Journal of medicinal chemistry, 1992-04, Vol.35 (8), p.1339-1344

1992

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Retraction

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (20), p.12069-12069

1998

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Retraction

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (20), p.12069-12069

1998

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The PKC inhibitor CGP 41251 reverses P-gp mediated multidrug resistance and synergizes with adriamycin: 64

Anti-cancer drugs, 1994-09, Vol.5, p.28

1994

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A Novel Storage and Retrieval Concept for Compound Collections on Dry Film

Journal of Laboratory Automation, 2005-04, Vol.10 (2), p.88-97

2005

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Protein kinase C inhibitor staurosporin derivative CGP 41251 reverses MDR in murine and human cancer cell lines: 65

Anti-cancer drugs, 1994-09, Vol.5, p.29

1994

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Die Stiftung Emilia Guggenheim-Schnurr der Naturforschenden Gesellschaft in Basel

Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90

Correction to “Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90”

Metastatic disease: A drug discovery perspective

Abstract 3779: Treatment of experimental brain metastasis of human breast cancer by macitentan, a dual antagonist of endothelin receptors combined with paclitaxel

Stable Amplification of the S-Adenosylmethionine Decarboxylase Gene in Chinese Hamster Ovary Cells (∗)

Antitumor Compound Testing in Glioblastoma Organotypic Brain Cultures

Abstract 5481: Therapy of human LN229 glioblastoma growing in the brain of nude mice by Macitentan, a dual endothelin receptor A and B antagonist, combined with Temozolomide

Antivascular Therapy for Multidrug-Resistant Ovarian Tumors by Macitentan, a Dual Endothelin Receptor Antagonist

Abstract 4274: Characterization and drug sensitivity testing of HTS compatible cancer microtissues

Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer

Macitentan (ACT-064992), a Tissue-Targeting Endothelin Receptor Antagonist, Enhances Therapeutic Efficacy of Paclitaxel by Modulating Survival Pathways in Orthotopic Models of Metastatic Human Ovarian Cancer12

Antivascular Therapy for Multidrug-Resistant Ovarian Tumors by Macitentan, a Dual Endothelin Receptor Antagonist1

The protein kinase C inhibitor CGP 41251, a staurosporine derivative with antitumor activity, reverses multidrug resistance

Reversal of multidrug resistance by the staurosporine derivatives CGP 41251 and CGP 42700

Experimental induction of testicular teratomas in dissociated–reaggregated chimaeric gonads

Thiazolidine-diones. Biochemical and biological activity of a novel class of tyrosine protein kinase inhibitors

S-Adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogs of methylglyoxal bis(guanylhydrazone)

4-Amidinoindan-1-one 2'-amidinohydrazone: a new potent and selective inhibitor of S-adenosylmethionine decarboxylase

2-Substituted 3-(aminooxy)propanamines as inhibitors of ornithine decarboxylase: synthesis and biological activity

Retraction

Retraction

The PKC inhibitor CGP 41251 reverses P-gp mediated multidrug resistance and synergizes with adriamycin: 64

A Novel Storage and Retrieval Concept for Compound Collections on Dry Film

Protein kinase C inhibitor staurosporin derivative CGP 41251 reverses MDR in murine and human cancer cell lines: 65

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