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Biased β2‐adrenoceptor signalling in heart failure: pathophysiology and drug discovery

British journal of pharmacology, 2015-12, Vol.172 (23), p.5444-5456

2015

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β-Adrenergic receptor subtype signaling in heart： From bench to bedside

Acta pharmacologica Sinica, 2012-03, Vol.33 (3), p.335-341

2012

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CaMKII-δ9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair

Nature cell biology, 2019-09, Vol.21 (9), p.1152-1163

2019

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A chemical approach for global protein knockdown from mice to non-human primates

Cell discovery, 2019-02, Vol.5 (1), p.10-10, Article 10

2019

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Atrial Fibrillation Known Before or Detected After Stroke Share Similar Risk of Ischemic Stroke Recurrence and Death

Stroke (1970), 2019-05, Vol.50 (5), p.1124-1129

2019

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Functional and Adaptive Significance of Promoter Mutations That Affect Divergent Myocardial Expressions of TRIM72 in Primates

Molecular biology and evolution, 2021-07, Vol.38 (7), p.2930-2945

2021

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Integration of the metabolome and transcriptome reveals the metabolites and genes related to nutritional and medicinal value in Coriandrum sativum

Journal of Integrative Agriculture, 2021-07, Vol.20 (7), p.1807-1818

2021

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Dynamic changes in insulin and glucagon during disease progression in rhesus monkeys with obesity‐related type 2 diabetes mellitus

Diabetes, obesity & metabolism, 2019-05, Vol.21 (5), p.1111-1120

2019

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Mitofusin 2 Triggers Vascular Smooth Muscle Cell Apoptosis via Mitochondrial Death Pathway

Circulation research, 2007-11, Vol.101 (11), p.1113-1122

2007

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Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion

Molecular metabolism (Germany), 2024-01, Vol.79, p.101847-101847, Article 101847

2024

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Targeting ANGPTL3 by GalNAc-conjugated siRNA ANGsiR10 lowers blood lipids with long-lasting and potent efficacy in mice and monkeys

Molecular therapy. Nucleic acids, 2023-03, Vol.31, p.68-77

2023

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Mitofusin-2 Is a Major Determinant of Oxidative Stress-mediated Heart Muscle Cell Apoptosis

The Journal of biological chemistry, 2007-08, Vol.282 (32), p.23354-23361

2007

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Myocardial glycogen dynamics: New perspectives on disease mechanisms

Clinical and experimental pharmacology & physiology, 2015-04, Vol.42 (4), p.415-425

2015

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Advances in receptor conformation research: the quest for functionally selective conformations focusing on the β2‐adrenoceptor

British journal of pharmacology, 2015-12, Vol.172 (23), p.5477-5488

2015

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sRAGE alleviates SARS-CoV-2-induced pneumonia in hamster

Signal transduction and targeted therapy, 2022-02, Vol.7 (1), p.36-36, Article 36

2022

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Dual Modulation of Cell Survival and Cell Death by β2-Adrenergic Signaling in Adult Mouse Cardiac Myocytes

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (4), p.1607-1612

2001

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Protocol for cell preparation and gene delivery in HEK293T and C2C12 cells

STAR protocols, 2021-09, Vol.2 (3), p.100497-100497, Article 100497

2021

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Renal Dysfunction and In-Hospital Outcomes in Patients With Acute Ischemic Stroke After Intravenous Thrombolytic Therapy

Journal of the American Heart Association, 2019-10, Vol.8 (20), p.e012052

2019

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Discovery of β-arrestin-biased β2-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives

Acta pharmacologica Sinica, 2019-08, Vol.40 (8), p.1095-1105

2019

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Evaluation of AMPK activity in mice by measuring activator-induced glucose uptake

STAR protocols, 2021-09, Vol.2 (3), p.100496-100496, Article 100496

2021

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Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys

Diabetology and metabolic syndrome, 2018-09, Vol.10 (1), p.68-68, Article 68

2018

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Making An Impact on Clinical Practice and Research in China

The New England journal of medicine, 2016-12, Vol.375 (24), p.2391-2392

2016

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ADRB2 polymorphism Arg16Gly modifies the natural outcome of heart failure and dictates therapeutic response to β-blockers in patients with heart failure

Cell discovery, 2018-10, Vol.4 (1), p.57-13, Article 57

2018

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β1/β2-Adrenergic Receptor Heterodimerization Regulates β2-Adrenergic Receptor Internalization and ERK Signaling Efficacy

The Journal of biological chemistry, 2002-09, Vol.277 (38), p.35402-35410

2002

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Ca2+/Calmodulin Kinase II–Dependent Phosphorylation of Ryanodine Receptors Suppresses Ca2+ Sparks and Ca2+ Waves in Cardiac Myocytes

Circulation research, 2007-02, Vol.100 (3), p.399-407

2007

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Biased β2‐adrenoceptor signalling in heart failure: pathophysiology and drug discovery

β-Adrenergic receptor subtype signaling in heart： From bench to bedside

CaMKII-δ9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair

A chemical approach for global protein knockdown from mice to non-human primates

Atrial Fibrillation Known Before or Detected After Stroke Share Similar Risk of Ischemic Stroke Recurrence and Death

Functional and Adaptive Significance of Promoter Mutations That Affect Divergent Myocardial Expressions of TRIM72 in Primates

Integration of the metabolome and transcriptome reveals the metabolites and genes related to nutritional and medicinal value in Coriandrum sativum

Dynamic changes in insulin and glucagon during disease progression in rhesus monkeys with obesity‐related type 2 diabetes mellitus

Mitofusin 2 Triggers Vascular Smooth Muscle Cell Apoptosis via Mitochondrial Death Pathway

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion

Targeting ANGPTL3 by GalNAc-conjugated siRNA ANGsiR10 lowers blood lipids with long-lasting and potent efficacy in mice and monkeys

Mitofusin-2 Is a Major Determinant of Oxidative Stress-mediated Heart Muscle Cell Apoptosis

Myocardial glycogen dynamics: New perspectives on disease mechanisms

Advances in receptor conformation research: the quest for functionally selective conformations focusing on the β2‐adrenoceptor

sRAGE alleviates SARS-CoV-2-induced pneumonia in hamster

Dual Modulation of Cell Survival and Cell Death by β2-Adrenergic Signaling in Adult Mouse Cardiac Myocytes

Protocol for cell preparation and gene delivery in HEK293T and C2C12 cells

Renal Dysfunction and In-Hospital Outcomes in Patients With Acute Ischemic Stroke After Intravenous Thrombolytic Therapy

Discovery of β-arrestin-biased β2-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives

Evaluation of AMPK activity in mice by measuring activator-induced glucose uptake

Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys

Making An Impact on Clinical Practice and Research in China

ADRB2 polymorphism Arg16Gly modifies the natural outcome of heart failure and dictates therapeutic response to β-blockers in patients with heart failure

β1/β2-Adrenergic Receptor Heterodimerization Regulates β2-Adrenergic Receptor Internalization and ERK Signaling Efficacy

Ca2+/Calmodulin Kinase II–Dependent Phosphorylation of Ryanodine Receptors Suppresses Ca2+ Sparks and Ca2+ Waves in Cardiac Myocytes

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