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Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation

Journal of controlled release, 2012-12, Vol.164 (3), p.364-369

2012

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Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats

Journal of drug targeting, 2014-06, Vol.22 (5), p.460-467

2014

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Polymeric Nanoparticles for Drug Delivery in Osteoarthritis

Pharmaceutics, 2022-11, Vol.14 (12), p.2639

2022

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Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets

Molecular therapy. Nucleic acids, 2024-03, Vol.35 (1), p.102159-102159, Article 102159

2024

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Cell uptake and intracellular trafficking of bioreducible poly(amidoamine) nanoparticles for efficient mRNA translation in chondrocytes

Frontiers in bioengineering and biotechnology, 2023-11, Vol.11, p.1290871-1290871

2023

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Polymeric Nanoparticles Enable mRNA Transfection and Its Translation in Intervertebral Disc and Human Joint Cells, Except for M1 Macrophages

Pharmaceutics, 2024-04, Vol.16 (4), p.438

2024

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In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint

Biomedicines, 2021-07, Vol.9 (7), p.794

2021

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Liposome technologies and drug delivery to the CNS

Drug discovery today. Technologies, 2016-06, Vol.20, p.53-58

Rip, Jaap

2016

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Targeted blood-to-brain drug delivery --10 key development criteria

Current pharmaceutical biotechnology, 2012-09, Vol.13 (12), p.2328-2339

2012

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In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes

Pharmaceutical research, 2016-01, Vol.33 (1), p.177-185

2016

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The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2606-2613

2017

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In Vivo Quantitative Understanding of PEGylated Liposome’s Influence on Brain Delivery of Diphenhydramine

Molecular pharmaceutics, 2018-12, Vol.15 (12), p.5493-5500

2018

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Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo

Drug discovery today. Technologies, 2016-06, Vol.20, p.59-69

2016

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Systemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammation

Investigative ophthalmology & visual science, 2014-04, Vol.55 (4), p.2788-2794

2014

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Blood-to-Brain Drug Delivery Using Nanocarriers

Drug Delivery to the Brain, p.501-526

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Lipoprotein lipase S447X: a naturally occurring gain-of-function mutation

Arteriosclerosis, thrombosis, and vascular biology, 2006-06, Vol.26 (6), p.1236-1245

2006

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Drug Delivery to the Brain: Physiological Concepts, Methodologies and Approaches

2nd ed. 2022

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Enhanced brain drug delivery: safely crossing the blood–brain barrier

Drug discovery today. Technologies, 2012, Vol.9 (2), p.e155-e160

2012

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Abstract 5687: Development of glutathione pegylated liposomal doxorubicin (2B3-101) for the treatment of brain cancer

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.5687-5687

2012

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Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation

Human gene therapy, 2006-05, Vol.17 (5), p.487-499

2006

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Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPLS447X beneficial mutation

Human gene therapy, 2004-09, Vol.15 (9), p.906-919

2004

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First evidence of efficacy in brain following intravenous injections of Brain-Targeted Liposome-Enzyme in the MPS II mouse model

Molecular genetics and metabolism, 2011-02, Vol.102 (2), p.S40-S40

2011

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Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study

Arteriosclerosis, thrombosis, and vascular biology, 2006-03, Vol.26 (3), p.637-642

2006

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Abstract 5537: GSH-conjugation improves efficacy of Doxil against intracranial xenografts

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5537-5537

2010

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Adeno-associated virus LPL S447X gene therapy in LDL receptor knockout mice

Atherosclerosis, 2007, Vol.194 (1), p.55-61

2007

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Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation

Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats

Polymeric Nanoparticles for Drug Delivery in Osteoarthritis

Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets

Cell uptake and intracellular trafficking of bioreducible poly(amidoamine) nanoparticles for efficient mRNA translation in chondrocytes

Polymeric Nanoparticles Enable mRNA Transfection and Its Translation in Intervertebral Disc and Human Joint Cells, Except for M1 Macrophages

In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint

Liposome technologies and drug delivery to the CNS

Targeted blood-to-brain drug delivery --10 key development criteria

In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes

The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study

In Vivo Quantitative Understanding of PEGylated Liposome’s Influence on Brain Delivery of Diphenhydramine

Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo

Systemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammation

Blood-to-Brain Drug Delivery Using Nanocarriers

Lipoprotein lipase S447X: a naturally occurring gain-of-function mutation

Drug Delivery to the Brain: Physiological Concepts, Methodologies and Approaches

Enhanced brain drug delivery: safely crossing the blood–brain barrier

Abstract 5687: Development of glutathione pegylated liposomal doxorubicin (2B3-101) for the treatment of brain cancer

Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation

Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPLS447X beneficial mutation

First evidence of efficacy in brain following intravenous injections of Brain-Targeted Liposome-Enzyme in the MPS II mouse model

Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study

Abstract 5537: GSH-conjugation improves efficacy of Doxil against intracranial xenografts

Adeno-associated virus LPL S447X gene therapy in LDL receptor knockout mice

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